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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Noninvasive ventilation acutely modifies heart rate variability in chronic obstructive pulmonary disease patients

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Author(s):
Borghi-Silva, Audrey [1] ; Reis, Michel Silva [1] ; Mendes, Renata Gonqalves [1] ; Falasco Pantoni, Camila Bianca [1] ; Simoes, Rodrigo Polaquini [1] ; Barreto Martins, Luis Eduardo [2] ; Catai, Aparecida Maria [1]
Total Authors: 7
Affiliation:
[1] Univ Fed Sao Carlos, Cardiopulm Physiotherapy Lab, Dept Physiotherapy, BR-13565905 Sao Carlos, SP - Brazil
[2] Univ Estadual Campinas, Exercise Physiol Lab, Fac Phys Educ, Campinas, SP - Brazil
Total Affiliations: 2
Document type: Journal article
Source: RESPIRATORY MEDICINE; v. 102, n. 8, p. 1117-1123, AUG 2008.
Web of Science Citations: 29
Abstract

Objective: The purpose of present study was to evaluate the acute effects of bi-level positive airway pressure (BiPAP) on heart rate variability (HRV) of stable chronic obstructive pulmonary disease patients (COPD). Methods: Nineteen mates with COPD (69 +/- 8 years and with forced expiratory volume in 1 s <50% of predicted) and eight healthy sedentary age-matched (69 years) males in the control group (CG) were evaluated during two conditions of controlled respiratory rate: spontaneous breathing (SB) and BiPAP (inspiratory and expiratory levels between 12-14 cmH(2)O and 4-6 cmH(2)O, respectively). Peripheral oxygen saturation (SpO(2)), end-tidal of carbon dioxide (ETCO2), systolic blood pressure (SBP) and R-R interval were obtained. HRV was analyzed by time (RMSSD and SDNN index) and frequency domains (high frequency - HF, low frequency - LF and HF/LF ratio). Results: Significant reduction of ETCO2 and SBP in both groups and increase of SpO(2) in COPD group was observed during BiPAP ventilation (p < 0.05). During spontaneous breathing, patients with COPD presented lower values of LF, LF/HF and higher values of HF when compared to CG (p < 0.05). However, HF was significantly reduced and LF increased during BiPAP ventilation (58 +/- 19-48 +/- 15 and 41 +/- 19-52 +/- 15un, respectively) in COPD group. Significant correlations between delta BiPAP-SB (Delta) ETCO2 and Delta HF were found (r = 0.89). (AU)

FAPESP's process: 05/59427-7 - Efeito da modulação autonômica cardíaca em pacientes submetidos à cirurgia de revascularização do miocárdio e programa de fisioterapia: fase I da reabilitação cardiovascular
Grantee:Audrey Borghi Silva
Support Opportunities: Regular Research Grants