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(Reference retrieved automatically from Google Scholar through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

A computational approach to characterization of bovine sperm chromatin alterations

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Author(s):
Beletti‚ ME ; Costa‚ L.F. ; Viana‚ MP
Total Authors: 3
Document type: Journal article
Source: BIOTECHNIC & HISTOCHEMISTRY; v. 79, n. 1, p. 17-23, 2004.
Abstract

We describe here a computational morphology-based approach to the investigation of possible causes of chromatin alterations in sperm. A comprehensive set of state-of-the-art and geometric measures are computationally extracted from toluidine blue stained images and analyzed to infer the possible processes leading to normal and abnormal chromatin formation while seeking a possible taxonomy of chromatin alterations and their influence on sperm head morphology. Using this methodology, we have identified higher chromatin fragility at some specific points of the sperm head. Despite the lack of correlation between morphologies of sperm head and chromatin structure, four main morphological types of chromatin alterations in bull spermatozoa have been identified and their possible causes discussed. (AU)

FAPESP's process: 99/12765-2 - Development and assessment of novel and accurate methods in shape analysis and computer vision
Grantee:Luciano da Fontoura Costa
Support Opportunities: Research Projects - Thematic Grants