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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Novel production method of porous surface Ti samples for biomedical application

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Author(s):
Reis de Vasconcellos, Luana Marotta [1] ; Oliveira, Fernanda Nascimento [1] ; Leite, Daniel de Oliveira [1] ; Oliveira de Vasconcellos, Luis Gustavo [1] ; do Prado, Renata Falchete [1] ; Ramos, Carolina Judica [1] ; de Alencastro Graca, Mario Lima [2] ; Alves Cairo, Carlos Alberto [1] ; Carvalho, Yasmin Rodarte [1]
Total Authors: 9
Affiliation:
[1] Univ Estadual Paulista UNESP, Dept Biosci & Oral Diag, Sao Jose dos Campos Sch Dent, BR-12245000 Sao Jose Dos Campos, SP - Brazil
[2] CTA, Div Mat, Air & Space Inst, BR-12245000 Sao Jose Dos Campos, SP - Brazil
Total Affiliations: 2
Document type: Journal article
Source: JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE; v. 23, n. 2, p. 357-364, FEB 2012.
Web of Science Citations: 19
Abstract

A porous implant material with adequate pore structure and the appropriate mechanical properties for bone ingrowth has long been sought. This article presents details of the development, characterization and in vivo evaluations of powder metallurgy-processed titanium samples exhibiting a dense core with an integrated porous surface for biomedical applications. A space-holder method was applied to investigate the effects of different percentages and particle sizes of the urea on bone neoformation in 30 rabbits. The samples were previously characterized using scanning electron microscopy and mechanical testing. After 8 and 12 weeks of implantation, bone ingrowth was histologically and histometrically analyzed and push-out testing was performed. This study demonstrated that the association of a dense core integrated with the greatest number of interconnected pores of the smallest size is a promising biomaterial for bone tissue engineering. This sample exhibits appropriate mechanical properties combined with increased bone ingrowth, providing enhanced resistance to displacement. (AU)

FAPESP's process: 05/03709-4 - Study of porous implants osseointegration: analysis of bone growth in pores, resistance of implant-bone interface and mechanical property of porous titanium
Grantee:Luana Marotta Reis de Vasconcellos
Support Opportunities: Scholarships in Brazil - Post-Doctoral