Determination of N-Acetylcysteine by Cyclic Voltammetry Using Modified Carbon Paste Electrode with Copper Nitroprusside Adsorbed on the 3-Aminopropylsilica

Author(s)

de Sa, Acelino Cardoso ^[1] ; Paim, Leonardo L. ^[2] ; Bicalho, Urquisa de Oliveira ; do Carmo, Devaney Ribeiro ^[1]

Affiliation

^[1] Univ Estadual Paulista, Fac Engn Ilha Solteira UNESP, Dept Fis & Quim, BR-15385000 Ilha Solteira, SP - Brazil

^[2] Univ Estadual Paulista, Inst Quim Araraquara UNESP, BR-14801970 Araraquara, SP - Brazil

• Document type: Journal article
• Source: International Journal of Electrochemical Science; v. 6, n. 9, p. 3754-3767, SEP 2011.
• Web of Science Citations: 10

Abstract

Copper nitroprusside was formed on aminopropylsilica silica gel (3-AS) surface (SiCuNP) previously prepared following two steps. These materials were thoroughly characterized by Infrared (FTIR) and cyclic voltammetry. The above techniques confirmed the successful formation of the copper nitroprusside on the silica surface. The cyclic voltammogram of CuNPSD were found to exhibit two redox couples with (E(theta)')(1) = 0.34 V; (E(theta)')(2) = 0.76 V vs. Ag/AgCl, KCl((sat)) (KCl = 1.0 mol L(-1); v = 20 mV s(-1)) attributed to the redox processes Cu((I))/Cu((II)) and Fe((II))(CN)(5)NO/Fe((III))(CN)(5)NO respectively. The second redox process ((E(theta)') 2 presented by the graphite paste electrode with SiCuNP shows electrocatalytic activity for the oxidation of N-acetylcysteine. The linear range for the determination of N-acetylcysteine was found between 9.9 x 10(-5) and 8.9 x 10(-4) mol L(-1) showing a detection limit of 4.18 x 10(-5) mol L(-1) and an amperometric sensitivity of 3.02 x 10(-2) A /mol(-1) L. (AU)

• FAPESP's process: 07/07700-7 - Development of sensors based on modified electrodes with pentacyanonitrosylferrates for determination of sulphur components in natural gas
• Grantee: Leonardo Lataro Paim
• Support Opportunities: Scholarships in Brazil - Doctorate