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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Cognitive impairment in antiphospholipid syndrome: evidence from animal models

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Author(s):
Appenzeller, Simone [1] ; Lapa, Aline Tamires [2] ; Guirau, Caio Rodrigues [1] ; de Carvalho, Jozelio Freire [3] ; Shoenfeld, Yehuda [4, 5]
Total Authors: 5
Affiliation:
[1] Univ Estadual Campinas, Fac Med Sci, Rheumatol Unit, Dept Med, Campinas, SP - Brazil
[2] Univ Estadual Campinas, UNICAMP, Program Child & Adolescent Hlth, Fac Med Sci, Campinas, SP - Brazil
[3] Clin Oncol CLION, Div Rheumatol, Salvador, BA - Brazil
[4] Chaim Sheba Med Ctr, Dept Med B, IL-52621 Tel Hashomer - Israel
[5] Chaim Sheba Med Ctr, Ctr Autoimmune Dis, IL-52621 Tel Hashomer - Israel
Total Affiliations: 5
Document type: Review article
Source: CLINICAL RHEUMATOLOGY; v. 31, n. 3, p. 403-406, MAR 2012.
Web of Science Citations: 5
Abstract

Although antiphospholipid syndrome (APS) is a multisystem prothrombotic condition, its inflammatory nature has been increasingly recognized in recent years. Stroke and transitory ischemic attacks are the neurological manifestations included in APS criteria, however many other neurological involvements have been attributed to antiphospholipid antibodies (aPL), such as seizures, transverse myelitis, and cognitive impairment. In this article we will review evidence from animal model that explain the role of aPL in cognition. (AU)

FAPESP's process: 09/06049-6 - Blood and cerebrospinal fluid biomarkers associated with structural and functional central nervous system abnormalities in Systemic lupus erythematosus
Grantee:Simone Appenzeller
Support Opportunities: Scholarships in Brazil - Young Researchers
FAPESP's process: 08/02917-0 - Blood and cerebrospinal fluid biomarkers associated with structural and functional central nervous system abnormalities in systemic lupus erythematosus
Grantee:Simone Appenzeller
Support Opportunities: Research Grants - Young Investigators Grants