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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Clinicopathological factors are predictors of distant metastasis from major salivary gland carcinomas

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Author(s):
Mariano, F. V. [1] ; da Silva, S. D. [2] ; Chulan, T. C. [2] ; de Almeida, O. P. [1] ; Kowalski, L. P. [2]
Total Authors: 5
Affiliation:
[1] Univ Campinas UNICAMP, Dept Oral Diag, Sch Dent Piracicaba, BR-13414018 Sao Paulo - Brazil
[2] AC Camargo Hosp, Dept Head & Neck Surg & Otorhinolaryngol, BR-01509900 Sao Paulo - Brazil
Total Affiliations: 2
Document type: Journal article
Source: International Journal of Oral and Maxillofacial Surgery; v. 40, n. 5, p. 504-509, MAY 2011.
Web of Science Citations: 30
Abstract

The risk of distant metastasis of salivary gland cancers has usually been associated with histological type, tumour size, and site. The aim of this study was to evaluate a series of patients with major salivary gland carcinomas in order to identify potential risk factors associated with distant metastasis. 255 patients treated for major salivary gland carcinoma in Brazil from 1953 to 2004 were reviewed. Clinical and treatment data were obtained from the medical records and histological features reviewed. 57 (22%) of 255 patients had distant metastasis. The lungs were the most common metastatic site (40 cases, 65%) and adenoid cystic carcinoma the most frequent histological type involved (27 cases, 47%). The percentage of tumours in the submandibular, parotid, and sublingual glands that presented distant metastasis was 42%, 20%, and 17%, respectively. These results provide evidences that clinicopathological factors (tumour site and histology) are significant predictors of distant metastasis in patients with major salivary gland carcinomas. (AU)