| Full text | |
| Author(s): |
Anna S. Nishiya
[1]
;
Gabriela Ribeiro-Dos-Santos
[2]
;
Leda Bassit
[3]
;
Roberto Focaccia
[4]
;
Dalton F. Chamone
[5]
;
Ester C. Sabino
[6]
Total Authors: 6
|
| Affiliation: | [1] Fundação Pró-Sangue. Hemocentro de São Paulo - Brasil
[2] Fundação Pró-Sangue. Hemocentro de São Paulo - Brasil
[3] Fundação Pró-Sangue. Hemocentro de São Paulo - Brasil
[4] Institute of Infectology Emílio Ribas - Brasil
[5] Fundação Pró-Sangue. Hemocentro de São Paulo - Brasil
[6] Fundação Pró-Sangue. Hemocentro de São Paulo - Brasil
Total Affiliations: 6
|
| Document type: | Journal article |
| Source: | Revista do Instituto de Medicina Tropical de São Paulo; v. 45, n. 4, p. 213-216, 2003-08-00. |
| Abstract | |
There has been several studies worldwide on phylogenetics and genotype distribution of the GB-virus C / Hepatitis G virus (GBV-C/HGV). However, in their great majority, those investigations were based on some epidemiologically linked group, rather than on a representative sampling of the general population. The present is a continuation of the first study in Brazil with such a population; it addresses the GBV-C/HGV phylogenetics and genotype distribution based on samples identified among more than 1,000 individuals of the city of São Paulo. For this purpose, a 728 bp fragment of the 5´non-coding region (5´NCR) of the viral genome, from 24 isolates, was sequenced and subjected to phylogenetic analysis. Genotypes 1, 2a and 2b were found at 8.3% (2/24), 50% (12/24) and 41.7% (10/24), respectively. In conclusion São Paulo displays a genotype distribution similar to the published data for other States and Regions of Brazil, endorsing the notion that types 1 and 2 would have entered the country with African and European people, respectively, since its earliest formation. (AU) | |