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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

(-)-7-Hydroxycassine: a New 2,6-Dialkylpiperidin-3-ol Alkaloid and other Constituents Isolated from Flowers and Fruits of Senna spectabilis (Fabaceae)

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Viegas Junior, Claudio [1] ; Pivatto, Marcos [2] ; de Rezende, Amanda [3] ; Hamerski, Lidilhone [3] ; Siqueira Silva, Dulce Helena [3] ; da Silva Bolzani, Vanderlan [3]
Total Authors: 6
[1] Univ Fed Alfenas, Inst Chem, Phytochem & Med Chem Lab LFQM, BR-37130000 Alfenas, MG - Brazil
[2] Univ Fed Uberlandia, Inst Chem, BR-38400902 Uberlandia, MG - Brazil
[3] Sao Paulo State Univ UNESP Julio de Mesquita Filh, Inst Chem, Dept Organ Chem, Nucleus Bioassays Biosynth & Ecophysiol Nat Prod, BR-14801970 Araraquara, SP - Brazil
Total Affiliations: 3
Document type: Journal article
Source: Journal of the Brazilian Chemical Society; v. 24, n. 2, p. 230-235, FEB 2013.
Web of Science Citations: 3

The phytochemical study of flowers and green fruits of Senna spectabilis furnished a new substituted 2,6-dialkylpiperidin-3-ol alkaloid, named (-)-7-hydroxycassine, along with five known piperidine alkaloids: (-)-cassine, (-)-spectaline, (-)-3-O-acetylspectaline, (-)-7-hydroxyspectaline and (-)-iso-6-spectaline. In addition to non-alkaloidal, chemical constituents from other chemical classes were also identified, including the steroid beta-sitosterol, the flavonoids luteolin and 3-methoxyluteolin, the triterpene betulinic acid and trans-cinnamic acid. To our knowledge, compounds are being reported for the first time in this species. (AU)

FAPESP's process: 03/02176-7 - Conservation and sustainable use of the diversity from Cerrado and Atlantic Forest: chemical diversity and prospecting for potential drugs - phase II
Grantee:Vanderlan da Silva Bolzani
Support type: BIOTA-FAPESP Program - Thematic Grants