Synthesis of unsymmetrical phthalocyanine derivatives and their interaction with mammary MCF7 cells

do Nascimento, F. B.; Manieri, T. M.; Cerchiaro, G.; Ribeiro, A. O.

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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Synthesis of unsymmetrical phthalocyanine derivatives and their interaction with mammary MCF7 cells

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Author(s):	do Nascimento, F. B. ^[1] ; Manieri, T. M. ^[1] ; Cerchiaro, G. ^[1] ; Ribeiro, A. O. ^[1] Total Authors: 4
Affiliation:	^[1] Fed Univ ABC UFABC, Ctr Nat Sci & Humanities, Santo Andre, SP - Brazil Total Affiliations: 1
Document type:	Journal article
Source:	DYES AND PIGMENTS; v. 99, n. 2, p. 316-322, NOV 2013.
Web of Science Citations:	10
Abstract
We report herein the synthesis and characterization of a group of unsymmetrical phthalocyanines modified with different combinations of hydrophobic and hydrophilic groups. Our results demonstrated that their solubility in polar media varies with the proportion of hydroxylated groups present in each structure and that the cell interactions and generation of reactive oxygen species in aqueous media change according to the hydrophobic to hydrophilic balance in the macrocycle. (C) 2013 Elsevier Ltd. All rights reserved. (AU)

FAPESP's process:	11/22561-9 - Phthalocyanines as photosensitizers in photodynamic therapy
Grantee:	Anderson Orzari Ribeiro
Support Opportunities:	Regular Research Grants

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