Broad HPV distribution in the genital region of men from the HPV infection in men (HIM) study

Author(s):Show less -

Sichero, Laura ^[1] ; Campbell, Christine M. Pierce ^[2] ; Ferreira, Silvaneide ^[1] ; Sobrinho, Joao S. ^[1] ; Baggio, Maria Luiza ^[3] ; Galan, Lenice ^[3] ; Silva, Roberto C. ^[4] ; Lazcano-Ponce, Eduardo ^[5] ; Giuliano, Anna R. ^[2] ; Villa, Luisa L. ^{[1, 6, 7]} ; Grp, HIM Study

Affiliation

^[1] Inst Canc Estado Sao Paulo ICESP, Ctr Translat Oncol, Mol Biol Lab, BR-01246000 Sao Paulo - Brazil

^[2] H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL 33612 - USA

^[3] Ludwig Inst Canc Res, BR-01409000 Sao Paulo - Brazil

^[4] Ctr Referencia & Treinamento DST Aids, BR-04121000 Sao Paulo - Brazil

^[5] Inst Nacl Salud Publ, Cuernavaca 62508, Morelos - Mexico

^[6] Univ Sao Paulo, Sch Med, Dept Radiol & Oncol, BR-05403900 Sao Paulo - Brazil

^[7] Santa Casa Misericordia Sao Paulo, HPV Inst, BR-01223001 Sao Paulo - Brazil

• Document type: Journal article
• Source: VIROLOGY; v. 443, n. 2, p. 214-217, SEP 1 2013.
• Web of Science Citations: 27

Abstract

The HPV infection in men (HIM) study examines the natural history of genital HPV infection in men. Genotyping methods used in this study identify 37 alpha-HPV types; however, the viral type could not be identified in approximately 22% of male genital specimens that were HPV PCR positive. Our aim was to genotype HPV-unclassified specimens by sequencing PGMY09/11, GP5+/6+ or FAP59/64 PCR products. Using this approach we were able to detect 86 unique HPV types among 508 of 931 specimens analyzed. We report for the first time the presence of a broad range of alpha-, beta- and gamma-HPV at the male genitals. (C) 2013 Elsevier Inc. All rights reserved. (AU)

• FAPESP's process: 10/15282-3 - Diversity of HPV types in the male genital region
• Grantee: Laura Cristina Sichero Vettorazzo
• Support Opportunities: Regular Research Grants
• FAPESP's process: 08/57889-1 - Institute of Science and Technology to study Diseases Associated with Papillomavirus
• Grantee: Luisa Lina Villa
• Support Opportunities: Research Projects - Thematic Grants