Determination of steroids, caffeine and methylparaben in water using solid phase microextraction-comprehensive two dimensional gas chromatography-time of flight mass spectrometry

Author(s)

Lima Gomes, Paulo C. F. ^{[1, 2]} ; Barnes, Brian B. ^[2] ; Santos-Neto, Alvaro J. ^[1] ; Lancas, Fernando M. ^[1] ; Snow, Nicholas H. ^[2]

Affiliation

^[1] Univ Sao Paulo, Inst Chem Sao Carlos, BR-13560970 Sao Carlos, SP - Brazil

^[2] Seton Hall Univ, Ctr Acad Ind Partnership, Dept Chem & Biochem, S Orange, NJ 07079 - USA

• Document type: Journal article
• Source: Journal of Chromatography A; v. 1299, p. 126-130, JUL 19 2013.
• Web of Science Citations: 20

Abstract

Analysis of several emerging contaminants (steroids, caffeine and methylparaben) in water using automated solid-phase microextraction with comprehensive two dimensional gas chromatography coupled to time of flight mass spectrometry (SPME-GCxGC-ToF/MS) is presented. Experimental design was used to determine the best SPME extraction conditions and the steroids were not derivatized prior to injection. SPME-GCxGC-ToF/MS provided linear ranges from 0.6 to 1200 mu g L-1 and limits of detection and quantitation from 0.02 to 100 mu g L-1. A series of river water samples obtained locally were subjected to analysis. SPME-GCxGC-ToF/MS is readily automated, straightforward and competitive with other methods for low level analysis of emerging contaminants (C) 2013 Elsevier B.V. All rights reserved. (AU)

• FAPESP's process: 05/59360-0 - Miniaturization of analytical instrumentation for separation techniques: sample preparation and printing of result
• Grantee: Fernando Mauro Lanças
• Support Opportunities: Research Projects - Thematic Grants
• FAPESP's process: 07/03844-4 - Simultaneous analysis of multi-residue antibiotics in water and sediments by headspace bar sorptive extraction with in situ derivatization coupled to GC / MS
• Grantee: Paulo Clairmont Feitosa de Lima Gomes
• Support Opportunities: Scholarships in Brazil - Doctorate (Direct)