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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Silver(I) complexes with symmetrical Schiff bases: Synthesis, structural characterization, DFT studies and antimycobacterial assays

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Author(s):
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Paiva, Isabela L. [1] ; de Carvalho, Gustavo S. G. [1] ; da Silva, Adilson D. [1] ; Corbi, Pedro P. [2] ; Bergamini, Fernando R. G. [2] ; Formiga, Andre L. B. [2] ; Diniz, Renata [1] ; do Carmo, Weberton R. [1] ; Leite, Clarice Q. F. [3] ; Pavan, Fernando R. [3] ; Cuin, Alexandre [1]
Total Authors: 11
Affiliation:
[1] Univ Fed Juiz de Fora, Inst Ciencias Exatas, Dept Quim, BR-36036900 Juiz de Fora, MG - Brazil
[2] Univ Estadual Campinas, UNICAMP, Inst Quim, BR-13083970 Campinas, SP - Brazil
[3] UNESP, Fac Ciencias Farmaceut, Dept Ciencias Biol, BR-14800900 Araraquara, SP - Brazil
Total Affiliations: 3
Document type: Journal article
Source: Polyhedron; v. 62, p. 104-109, OCT 7 2013.
Web of Science Citations: 12
Abstract

Synthesis, structural and spectroscopic characterizations, molecular modeling and antimycobacterial assays of new silver(I) complexes with two Schiff bases - MBDA and MBDB - are reported. The complexes {[}Ag(MBDA)(2)]NO3, or AgMBDA, and {[}Ag(MBDB)NO3] or AgMBDB, were obtained by the reaction of the respective ligands with silver(I) nitrate in methanol. The Schiff bases were previously obtained by mixing ethylenediamine or 1,3-diaminopropane with p-anisaldehyde. The characterizations of the complexes were based on elemental (C, H and N) and thermal (TG-DTA) analyses and C-13 and H-1 NMR and FT-IR spectroscopic measurements, as well as X-ray structure determination for AgMBDA. Spectroscopic data predicted by DFT calculations are in agreement with the experimental data for the AgMBDA complex. The AgMBDA complex has a monomeric structure with a molar proportion 1:2 Ag/ligand, while AgMBDB presents a 1:1 proportion. The complexes AgMBDA and AgMBDB showed to be more effective against Mycobacterium tuberculosis than antibacterial agent silver sulfadiazine - SSD. (c) 2013 Elsevier Ltd. All rights reserved. (AU)

FAPESP's process: 11/11593-7 - Research for new drugs against tuberculosis: laboratory improvement to perform pre-clinical trials
Grantee:Fernando Rogério Pavan
Support Opportunities: Scholarships in Brazil - Post-Doctoral
FAPESP's process: 09/06499-1 - Determination of in vitro and in vivo anti-tuberculosis activity of phosphines/diimines Ru (II) complexes
Grantee:Clarice Queico Fujimura Leite
Support Opportunities: Regular Research Grants
FAPESP's process: 12/08230-2 - Synthesis, characterization and pharmacological studies of Ag(I), Au(I), Pt(II) and Pd(II) complexes with bioactive ligands
Grantee:Pedro Paulo Corbi
Support Opportunities: Regular Research Grants