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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

A Comparative Study Between Two Different Conventional Working Electrodes for Detection of Delta(9)-Tetrahydrocannabinol Using Square-Wave Voltammetry: a New Sensitive Method for Forensic Analysis

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Author(s):
Balbino, Marco A. [1] ; Eleoterio, Izabel C. [1] ; de Oliveira, Laura S. [1] ; de Menezes, Matheus M. T. [1] ; de Andrade, Jose Fernando [1] ; Ipolito, Antonio Jose [2] ; de Oliveira, Marcelo F. [1]
Total Authors: 7
Affiliation:
[1] Univ Sao Paulo, Dept Quim, Fac Filosofia Ciencias & Letras Ribeirao Preto, BR-14040901 Ribeirao Preto, SP - Brazil
[2] Superintendencia Policia Tecn Cient Estado Sao Pa, Nucleo Pericias Criminalist Ribeirao Preto, BR-14015040 Ribeirao Preto, SP - Brazil
Total Affiliations: 2
Document type: Journal article
Source: Journal of the Brazilian Chemical Society; v. 25, n. 3, p. 589-596, MAR 2014.
Web of Science Citations: 6
Abstract

Marijuana is a widely consumed illicit drug. Therefore, drug dealers have sought new ways to mask its forensic (spot test) analysis. In this article we describe a methodology for delta-9-tetrahydrocannabinol (Delta(9)-THC) detection by square-wave voltammetric (SWV) analysis in organic medium (N,N-dimethylformamide) using tetrabutylammonium tetrafluoroborate (TBATFB) as supporting electrolyte, and glassy carbon and platinum disc as working electrode. Applying a potential of -0.5 +/- 0.01 V vs. Ag/AgCl, KCl(sat), we detected a well-defined anodic peak current after the pre-concentration step; Delta(9)-THC detection presented linear dependence at concentrations ranging from 1.0 x 10(-9) mol L-1 to 2.2 x 10(-8) mol L-1, with a linear correlation coefficient 0.999 and a detection limit of 6.2 x 10(-10) mol L-1, using the glassy carbon disc working electrode. These results confirm that optimized SWV technique using glassy carbon disc working electrode enables qualitative analysis of Delta(9)-THC at concentrations higher than 1.0 nmol L-1. (AU)

FAPESP's process: 12/00084-7 - Development of chemically modified electrodes for the voltammetric determination of cocaine, MDMA, LSD, and D-9-tetrahydrocannabinol in samples of forensic interest
Grantee:Marcelo Firmino de Oliveira
Support Opportunities: Regular Research Grants