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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Synthesis of Alkaloids: Recent Advances in the Synthesis of Phenanthroindolizidine Alkaloids

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Author(s):
Burtoloso, Antonio C. B. [1] ; Bertonha, Ariane F. [1] ; Rosset, Isac G. [1]
Total Authors: 3
Affiliation:
[1] Univ Sao Paulo, Inst Quim Sao Carlos, BR-13560970 Sao Carlos, SP - Brazil
Total Affiliations: 1
Document type: Review article
Source: CURRENT TOPICS IN MEDICINAL CHEMISTRY; v. 14, n. 2, p. 191-199, JAN 2014.
Web of Science Citations: 16
Abstract

Phenanthroindolizidine alkaloids are a well-known class of compounds due to their interesting biological activities, especially anticancer ones. Represented by more than 60 substances, they are mainly isolated from plants of the Moraceae and Asclepiadaceae families. In the last 30 years, a great effort has been made aiming the synthesis of these compounds and analogues to be applied in medicinal chemistry. This short review will highlight recent contributions in the synthesis of these compounds, covering the years 2009-2012. (AU)

FAPESP's process: 10/18801-1 - Divergent synthesis of pyrrolidine alkaloids from ALFA,BETAUNSATURATED diazoketones as bifunctional reagents. application in the total synthesis of (±)-PREUSSIN
Grantee:Isac George Rosset
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 12/04685-5 - New synthetic methodologies for the construction of pyrrolidine, piperidine and indolizidine systems
Grantee:Antonio Carlos Bender Burtoloso
Support type: Regular Research Grants
FAPESP's process: 11/15903-0 - Studies towards the synthesis of Phenantroindolizidines
Grantee:Ariane Fernandes Bertonha
Support type: Scholarships in Brazil - Master