| Full text | |
| Author(s): |
Total Authors: 3
|
| Affiliation: | [1] Univ Sao Paulo, Inst Quim Sao Carlos, BR-13560970 Sao Carlos, SP - Brazil
Total Affiliations: 1
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| Document type: | Review article |
| Source: | CURRENT TOPICS IN MEDICINAL CHEMISTRY; v. 14, n. 2, p. 191-199, JAN 2014. |
| Web of Science Citations: | 16 |
| Abstract | |
Phenanthroindolizidine alkaloids are a well-known class of compounds due to their interesting biological activities, especially anticancer ones. Represented by more than 60 substances, they are mainly isolated from plants of the Moraceae and Asclepiadaceae families. In the last 30 years, a great effort has been made aiming the synthesis of these compounds and analogues to be applied in medicinal chemistry. This short review will highlight recent contributions in the synthesis of these compounds, covering the years 2009-2012. (AU) | |
| FAPESP's process: | 10/18801-1 - DIVERGENT SYNTHESIS OF PYRROLIDINE ALKALOIDS FROM ALFA,BETAUNSATURATED DIAZOKETONES AS BIFUNCTIONAL REAGENTS. APPLICATION IN THE TOTAL SYNTHESIS OF (±)-PREUSSIN |
| Grantee: | Isac George Rosset |
| Support type: | Scholarships in Brazil - Doctorate |
| FAPESP's process: | 12/04685-5 - New synthetic methodologies for the construction of pyrrolidine, piperidine and indolizidine systems |
| Grantee: | Antonio Carlos Bender Burtoloso |
| Support type: | Regular Research Grants |
| FAPESP's process: | 11/15903-0 - Studies Towards the Synthesis of Phenantroindolizidines |
| Grantee: | Ariane Fernandes Bertonha Delezuk |
| Support type: | Scholarships in Brazil - Master |