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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Clinical Comparison of the Effectiveness of Single-file Reciprocating Systems and Rotary Systems for Removal of Endotoxins and Cultivable Bacteria from Primarily Infected Root Canals

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Martinho, Frederico C. [1] ; Gomes, Ana P. M. [1] ; Fernandes, Aleteia M. M. [1] ; Ferreira, Nadia S. [1] ; Endo, Marcos S. [1] ; Freitas, Lilian E. [1] ; Camoes, Izabel C. G. [2]
Total Authors: 7
[1] State Univ Sao Paulo, UNESP, Sao Jose dos Campos Dent Sch, Endodont Div, Dept Restorat Dent, BR-12245000 Sao Paulo - Brazil
[2] Univ Fed Fluminense, Dept Restorat Dent, Endodont Div, Niteroi, RJ - Brazil
Total Affiliations: 2
Document type: Journal article
Source: JOURNAL OF ENDODONTICS; v. 40, n. 5, p. 625-629, MAY 2014.
Web of Science Citations: 18

Introduction: This clinical study was conducted to compare the effectiveness of single-file reciprocating systems and rotary systems in removing endotoxins and cultivable bacteria from primarily infected root canals. Methods: Forty-eight primarily infected root canals were selected and randomly divided into 4 groups: WaveOne (Dentsply Maillefer, Ballaigues, Switzerland) (n = 12); Reciproc (VDW, Munich, Germany) (n = 12), ProTaper (Dentsply Maillefer) (n = 12), and Mtwo (VDW) (n = 12). Samples were collected before and after chemomechanical preparation. The irrigation was performed by using 2.5% sodium hypochlorite. A chromogenic limulus amebocyte lysate assay test was used to quantify endotoxins. Culture techniques were used to determine bacterial colony-forming unit counts. Results: In the baseline samples (ie, samples collected before chemomechanical preparation), endotoxins and cultivable bacteria were recovered from 100% of the root canal samples. No differences were found in the median percentage values of endotoxin reduction achieved with reciprocating systems (ie, WaveOne {[}95.15%] and Reciproc {[}96.21%]) and with rotary systems (ie, ProTaper {[}97.98%] and Mtwo {[}96.34%]) (P < .05). Both single-file reciprocating systems (ie, WaveOne {[}99.45%] and Reciproc {[}99.93%]) and rotary systems (ProTaper {[}99.85%] and Mtwo {[}99.41%]) were effective in reducing the cultivable bacteria (all P < .05). Moreover, the culture analysis revealed no differences in bacterial load reduction (P > .05). Conclusions: Both single-file reciprocating systems (ie, WaveOne and Reciproc instruments) and rotary systems (ie, ProTaper and Mtwo instruments) showed similar effectiveness in reducing endotoxins and cultivable bacteria from primarily infected root canals, but they were not able to eliminate them from all root canals analyzed. (AU)

FAPESP's process: 12/19536-5 - Investigation of potential biomarkers for ventilator-associated pneumina in intensive care unit patients under invasive mechanical ventilation
Grantee:Frederico Canato Martinho
Support type: Regular Research Grants