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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Isolation and molecular characterization of Brazilian turkey reovirus from immunosuppressed young poults

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Author(s):
Rosa, Ana Carolina G. [1] ; Ferreira, Helena Lage [2] ; Gomes, Deriane Elias [1] ; Taparo, Cilene Vidovix [1] ; Cardoso, Tereza Cristina [1, 3]
Total Authors: 5
Affiliation:
[1] Univ Sao Paulo State, Fac Med Vet, Virol Lab, BR-16050680 Aracatuba, SP - Brazil
[2] FZEA USP, Dept Vet Med, BR-13635900 Pirassununga, SP - Brazil
[3] Curso Med Vet, Dept Apoio Prod & Saude Anim, BR-16050680 Aracatuba, SP - Brazil
Total Affiliations: 3
Document type: Journal article
Source: ARCHIVES OF VIROLOGY; v. 159, n. 6, p. 1453-1457, JUN 2014.
Web of Science Citations: 2
Abstract

In this study, we investigated turkey reovirus (TReoV) in tissue samples from young birds, aged 15 days. RT-PCR for TReoV detected 3.3 % positive samples and TReoV was successfully isolated in Vero cells. Histological analysis of positive bursa of Fabricius (BF) revealed atrophied follicles and lymphocyte depletion. The number of CD8+, CD4+ and IgM+ cells was lower in infected BF. Phylogenetic analysis based on S3 gene showed that the Brazilian TReoV isolates clustered in a single group with 98-100 % similarity to TReoV strains circulating in the United States. This is the first indication that TReoV infection may be a contributing factor to immunosuppression in young birds. (AU)