Determination of serotonin on platinum electrode modified with carbon nanotubes/polypyrrole/silver nanoparticles nanohybrid

Author(s)

Cesarino, Ivana ^[1] ; Galesco, Heloisa V. ^[1] ; Machado, Sergio A. S. ^[1]

Affiliation

^[1] Univ Sao Paulo, Inst Quim Sao Carlos, BR-13560970 Sao Carlos, SP - Brazil

• Document type: Journal article
• Source: Materials Science & Engineering C-Materials for Biological Applications; v. 40, p. 49-54, JUL 1 2014.
• Web of Science Citations: 31

Abstract

A new sensor has been developed by a simple electrodeposition of multi-walled carbon nanotubes (MWCNT), polypyrrole (PPy) and colloidal silver nanoparticles on the platinum (Pt) electrode surface. The Pt/MWCNT/PPy/AgNPs electrode was applied to the detection of serotonin in plasmatic serum samples using differential pulse voltammetry (DPV). The synergistic effect of MWCNT/PPy/AgNPs nanohybrid formed yielded a LOD of 0.15 mu mol L-1 (26.4 mu g L-1). Reproducibility and repeatability values of 2.2% and 1.7%, respectively, were obtained compared to the conventional procedure. The proposed electrode can be an effective material to be used in biological analysis. (C) 2014 Elsevier B.V. All rights reserved. (AU)

• FAPESP's process: 12/19633-0 - Electrochemical Device Integrated with Carbon Nanotubes and Metal Nanoparticles for Analysis of Antibiotics in Wastewater
• Grantee: Ivana Cesarino
• Support Opportunities: Scholarships in Brazil - Post-Doctoral