Multi-user equipment approved in grant 2018/01550-8: electro-spray equipment to obtain bioactive compounds into nanostructures

• Grant number: 18/13408-1
• Support Opportunities: Multi-user Equipment Program
• Start date: August 01, 2018
• End date: July 31, 2025
• Field of knowledge: Agronomical Sciences - Food Science and Technology - Food Science
• Principal Investigator: Anna Rafaela Cavalcante Braga
• Grantee: Anna Rafaela Cavalcante Braga
• Host Institution: Instituto de Saúde e Sociedade (ISS). Universidade Federal de São Paulo (UNIFESP). Campus Baixada Santista. Santos , SP, Brazil
• Associated research grant: 18/01550-8 - Nanoestructures containing anthocyanins extracted from juçara pulp (Euterpe edulis Mart.): Interaction with lactic acid bacteria and bioavailability, AP.R
• EMU web page: https://www.unifesp.br/campus/san7/pesquisa/equipamentos-
• Type of equipment: Processos Físicos - Equipamentos de atmosfera controlada - Sprayer
• Manufacturer: Bioinicia
• Model: Fluidnatek LE-10

Abstract

The beneficial health properties had led to consumers growing interest in the consumption of products containing bioactive compounds. Among the more than 20 thousand species of plants present in the Atlantic Forest the jussara fruit (Euterpe edulis Mart.) stands out for its contents of phenolic and other bioactive compounds present in its composition. The biological action of phenolic compounds, particularly anthocyanins, has been demonstrated in in vitro experiments; however, this activity is not always reproduced in vivo, since it is dependent on factors such as absorption, metabolism, tissue distribution, composition intestinal microbiota and excretion. Intestinal microbiota has been targeted by many studies since their importance in all aspects of human health; however, the difficulty of improving the general population microbiota using fermentative processes to pre-digest biocompounds before its consumption is an interesting alternative to a wide the range of benefits of bioactive compounds. Instability against environmental stress and low bioaccessibility and bioavailability are the main limitations of anthocyanins industrial application, in this perspective, nanoencapsulated phenolic compounds can solve their restrictions. The objective of this project is to evaluate the production of nanostructures containing fermented anthocyanins extracts from jussara and to compare them, in terms of bioaccessibility, bioavailability with to nanocapsules of microorganisms added with fruit extract. (AU)

Scientific publications

(8)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

FRATELLI, CAMILLY; BURCK, MONIZE; ASSUMPCA AMARANT, MARINA CAMPOS; CAVALCANTE BRAGA, ANNA RAFAELA. Antioxidant potential of nature's ``something blue{''}: Something new in the marriage of biological activity and extraction methods applied to C-phycocyanin. TRENDS IN FOOD SCIENCE & TECHNOLOGY, v. 107, p. 309-323, JAN 2021. (18/01550-8, 20/06732-7, 18/13408-1)

RAMOS, SERGIANA DOS P.; GIACONIA, MICHELE A.; DO MARCO, JONAS T.; PAIVA, ROBERT DA S.; DE ROSSO, VERIDIANA V.; LEMES, AILTON C.; EGEA, MARIANA B.; ASSIS, MARCELO; MAZZO, TATIANA M.; LONGO, ELSON; et al. Development and Characterization of Electrospun Nanostructures Using Polyethylene Oxide: Potential Means for Incorporation of Bioactive Compounds. COLLOIDS AND INTERFACES, v. 4, n. 2, JUN 2020. (19/08975-7, 18/01550-8, 13/07296-2, 18/13408-1)

CAVALCANTE BRAGA, ANNA RAFAELA. Overcoming restrictions of bioactive compounds biological effects in food using nanometer-sized structures. FOOD HYDROCOLLOIDS, v. 107, OCT 2020. (18/01550-8, 18/13408-1)

GIACONIA, MICHELE AMENDOEIRA; RAMOS, SERGIANA DOS PASSOS; NEVES, BRUNA VITORIA; ALMEIDA, LARISSA; COSTA-LOTUFO, LETICIA; DE ROSSO, VERIDIANA VERA; CAVALCANTE BRAGA, ANNA RAFAELA. Nanofibers of Jussara Pulp: A Tool to Prevent the Loss of Thermal Stability and the Antioxidant Activity of Anthocyanins after Simulated Digestion. PROCESSES, v. 10, n. 11, p. 12-pg., 2022-11-01. (18/01550-8, 20/03560-0, 18/13408-1)

FRATELLI, CAMILLY; BURCK, MONIZE; ASSUMPCA AMARANT, MARINA CAMPOS; CAVALCANTE BRAGA, ANNA RAFAELA. Antioxidant potential of nature's "something blue": Something new in the marriage of biological activity and extraction methods applied to C-phycocyanin. TRENDS IN FOOD SCIENCE & TECHNOLOGY, v. 107, p. 15-pg., 2021-01-01. (18/13408-1, 20/06732-7, 18/01550-8)

NAKAMOTO, MONICA MASAKO; ASSIS, MARCELO; DE OLIVEIRA FILHO, JOSEMAR GONCALVS; BRAGA, ANNA RAFAELA CAVALCANTE. Spirulina application in food packaging: Gaps of knowledge and future trends. TRENDS IN FOOD SCIENCE & TECHNOLOGY, v. 133, p. 10-pg., 2023-02-08. (18/13408-1, 23/00857-0, 22/06293-9)

GIACONIA, MICHELE AMENDOEIRA; RAMOS, SERGIANA DOS PASSOS; FRATELLI, CAMILLY; ASSIS, MARCELO; MAZZO, TATIANA MARTELLI; LONGO, ELSON; DE ROSSO, VERIDIANA VERA; BRAGA, ANNA RAFAELA CAVALCANTE. Fermented Jussara: Evaluation of Nanostructure Formation, Bioaccessibility, and Antioxidant Activity. FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, v. 10, p. 11-pg., 2022-03-09. (20/06732-7, 18/13408-1, 19/08975-7, 13/07296-2, 18/01550-8, 20/03560-0)

RAMOS, SERGIANA DOS P.; GIACONIA, MICHELE A.; ASSIS, MARCELO; JIMENEZ, PAULA C.; MAZZO, TATIANA M.; LONGO, ELSON; DE ROSSO, VERIDIANA V.; BRAGA, ANNA R. C.. Uniaxial and Coaxial Electrospinning for Tailoring Jussara Pulp Nanofibers. Molecules, v. 26, n. 5, MAR 2021. (20/03560-0, 20/06732-7, 18/13408-1, 18/01550-8, 13/07296-2, 19/08975-7)