Acaricide evaluation of natural derivatives of Achyrocline satureioides and Schinus lentiscifolius in association with biotechnological products obtained from entomopathogenic fungi on the bovine tick Rhipicephalus (Boophilus) microplus

• Grant number: 18/14116-4
• Support Opportunities: Regular Research Grants
• Start date: November 01, 2018
• End date: January 31, 2021
• Field of knowledge: Health Sciences - Pharmacy
• Principal Investigator: Rosemeire Cristina Linhari Rodrigues Pietro
• Grantee: Rosemeire Cristina Linhari Rodrigues Pietro
• Host Institution: Faculdade de Ciências Farmacêuticas (FCFAR). Universidade Estadual Paulista (UNESP). Campus de Araraquara. Araraquara , SP, Brazil
• City of the host institution: Araraquara

Abstract

Despite the prominence and social and commercial importance of bovine breeding, infestations by ectoparasites, mainly by the tick Rhipicephalus (Boophilus) microplus, present a great economic impediment. Control is currently carried out using synthetic carrapaticides and its indiscriminate use has contributed to the emergence of resistance of the parasites most of the molecules available. Thus effective, economically viable and potentially safe alternatives should be investigated, such as the use of natural derivatives associated with entomopathogenic fungi. This project is part of the PhD student Rafaela Regina Fantatto and aims to evaluate plant extracts of Achyrocline satureioides and Schinus lentiscifolius associated with the entomopathogenic fungus Beauveria bassiana, as well as the enzyme chitinase produced by it, on different stages of the life cycle of the bovine tick R. (B.) microplus. Plant extracts will be phytochemically characterized by spectrometric and liquid chromatography techniques. The enzyme chitinase will be produced by B. bassiana fungus in liquid fermentation submerged in orbital shaker. Carrapaticidal activity of plant extracts, fungus, chitinase and associations thereof will be analyzed by in vitro tests such as immersion test of engorged females, impregnated paper contact test and larval immersion test. Preliminary studies have shown that crude ethanol extracts from A. satureioides and S. lentiscifolius do not inhibit B. bassiana at the concentration of 1.25 mg/ml, a promising result that allows the association tests proposed in this project. (AU)

Scientific publications

(4)

(The scientific publications listed on this page originate from the Web of Science or SciELO databases. Their authors have cited FAPESP grant or fellowship project numbers awarded to Principal Investigators or Fellowship Recipients, whether or not they are among the authors. This information is collected automatically and retrieved directly from those bibliometric databases.)

FANTATTO, RAFAELA REGINA; POLITI, FLAVIO AUGUSTO SANCHES; SORRECHIA, RODRIGO; PIETRO, ROSEMEIRE CRISTINA LINHARI RODRIGUES. In Vitro Activity of Ethanolic Extract and Essential Oil of Achyrocline satureioides Against Larvae of the Tick Rhipicephalus sanguineus. PARASITOLOGIA, v. 5, n. 4, p. 10-pg., 2025-11-07. (18/14116-4)

FANTATTO, RAFAELA REGINA; GAINZA, YOUSMEL ALEMAN; FIGUEIREDO, AMANDA; SORRECHIA, RODRIGO; DE SOUZA CHAGAS, ANA CAROLINA; LINHARI RODRIGUES PIETRO, ROSEMEIRE CRISTINA. The association of extracts of Achyrocline satureioides and the fungus Beauveria bassiana against the tick Rhipicephalus microplus. Experimental and Applied Acarology, v. 87, n. 4, p. 13-pg., 2022-08-24. (18/14116-4)

FANTATTO, RAFAELA REGINA; GOMES, ANNELIZE RODRIGUES; CONSTANTINI, JOAO VITOR CARVALHO; RODERO, CAMILA FERNANDA; CHORILLI, MARLUS; CHAGAS, ANA CAROLINA DE SOUZA; MELERO, ANA; PIETRO, ROSEMEIRE CRISTINA LINHARI RODRIGUES. Development and Evaluation of the Acaricidal Activity of Xantan Gum-Based Hydrogel and Polymeric Nanoparticles Containing Achyrocline satureioides Extract. GELS, v. 10, n. 10, p. 12-pg., 2024-10-01. (18/14116-4)

FANTATTO, RAFAELA REGINA; CONSTANTINI, JOAO VITOR CARVALHO; POLITI, FLAVIO AUGUSTO SANCHES; SORRECHIA, RODRIGO; MEDEIROS, CAMILA CRISTINA BACCETTI; LUIZ, MARCELA TAVARES; BECHARA, GERVASIO HENRIQUE; CHAGAS, ANA CAROLINA DE SOUZA; CHORILLI, MARLUS; PIETRO, ROSEMEIRE CRISTINA LINHARI RODRIGUES. Current Tick Control Strategies and Prospects for Using Nanotechnology as an Efficient Alternative-A Review. VETERINARY SCIENCES, v. 12, n. 2, p. 15-pg., 2025-02-01. (23/08269-0, 18/14116-4)