Apical-aortic blood pump

• Grant number: 17/25025-7
• Support Opportunities: Research Grants - Innovative Research in Small Business - PIPE
• Start date: October 01, 2018
• End date: June 30, 2019
• Field of knowledge: Engineering - Biomedical Engineering - Bioengineering
• Agreement: Secretary of State Government, State of São Paulo
• Principal Investigator: Rafael Nunes da Silva
• Grantee: Rafael Nunes da Silva
• Company: Rafael Nunes da Silva
• CNAE: Fabricação de instrumentos e materiais para uso médico e odontológico e de artigos ópticos
• City: São Bernardo do Campo
• Associated researchers: Bruno Utiyama da Silva ; Gustavo Caravita de Andrade
• Associated research grant(s): 19/10949-4 - Apex-aortic Blood Pump, AP.PIPE
• Associated scholarship(s): 18/24817-0 - Apical-aortic blood pump, BP.PIPE

Abstract

In the vast majority of countries, diseases of the cardiovascular system account for the highest number of deaths. This project aims to develop an Apex-Aortic Blood Pump (BSAA) to be used as a Ventricular Assist Device (VAD) in patients with severe heart disease or waiting for a heart transplant. In Brazil, access to this technology is difficult and costly. The imported devices cost 500 thousand reais. The estimated cost of this device will be around 10 thousand reais, facilitating its use, whether in the Brazilian public or private system. An implantable blood pump developed in Brazil will make it possible to disseminate this technology with great reduction in costs in relation to imported equipment. The BSAA will be developed with radial magnetic flux motor, which will make the lower bearing of the rotor suffer less wear, thus enabling the BSAA to be used in long term therapies. Unlike the original BSAA model, these new prototypes will use a radial motor available on the market. which will increase the durability of BSAA. The new prototype will be designed to maintain the characteristics of the original model to the maximum, mainly the external dimensions, because there is a limitation due to the intrathoracic space. The first prototypes of the BSAA adapted for the radial motor will be built by 3D printing at the Center for Engineering in Circulatory Assistance (CEAC) of the Bioengineering Division of the Adib Jatene Foundation (FAJ) using the Connex 350® printer (Stratasys®, Eden Prairie, USA). The goal will be achieved through In Vitro testing. It is hoped, in phase I of this project, to prove the technical feasibility of the production of this DAV. (AU)