Tridimencional modeling of a centrifugal blood pump to be used for temporary circulatory assistance

• Grant number: 14/09888-7
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Effective date (Start): August 01, 2014
• Effective date (End): July 31, 2015
• Field of knowledge: Engineering - Biomedical Engineering - Bioengineering
• Principal Investigator: Jeison Willian Gomes da Fonseca
• Grantee: Gustavo Caravita de Andrade
• Host Institution: Instituto Dante Pazzanese de Cardiologia (IDPC). Fundação Adib Jatene (FAJ). Secretaria da Saúde (São Paulo - Estado). São Paulo , SP, Brazil

Abstract

Cardiovascular diseases are the main cause of death in the world. Heart transplantation is often the only treatment for certain heart diseases, restoring patient´s normal clinical conditions. A Ventricular Assist Device (VAD) can be used for following applications: to maintain patient's life while waiting at line for heart transplantation (Bridge to Transplantation); during clinical treatment for better general patient health conditions (Bridge to Recovery); as unique available therapy for a specific patient (Destination Therapy) or as temporary circulatory support device (TCSD), at pre or post-operatory. One disposable centrifugal blood pump is being developed to be used as paracorporeal TCSD, with or without blood oxygenator. This TCSD must present high hydrodynamic performance, providing high flow and pressure capacity associated to a low cellular trauma (hemolisys). Development of such device will aim to avoid turbulent or stagnant flows, since these areas can increase hemolysis and thrombus formation, during blood pumping process. Dimensioning and developing 3D computational models will make feasible to prototype them by 3D printing, using PolyJet" technology, and will allow experimental studies, throughout "In Vitro" assays, for identification and correction of potential operational failures. (AU)