Advanced search
Start date

Studies on ovarian and uterine physiology and improvement of Assisted Reproduction Technologies to increase reproductive efficiency in cattle

Grant number: 18/03798-7
Support Opportunities:Research Projects - Thematic Grants
Duration: December 01, 2018 - November 30, 2023
Field of knowledge:Agronomical Sciences - Veterinary Medicine - Animal Reproduction
Principal Investigator:Roberto Sartori Filho
Grantee:Roberto Sartori Filho
Host Institution: Escola Superior de Agricultura Luiz de Queiroz (ESALQ). Universidade de São Paulo (USP). Piracicaba , SP, Brazil
Associated researchers:Alexandre Vaz Pires ; Danila Barreiro Campos ; Dante Pazzanese Duarte Lanna ; Eneiva Carla Carvalho Celeghini ; José Renato Silva Gonçalves ; Ky G. Pohler ; Leonardo de França e Melo ; Lucas Oliveira e Silva ; Luiz Lehmann Coutinho ; Manoel Francisco de Sá Filho ; Marcelo Marcondes Seneda ; Milo Wiltbank ; Natália Picoli Folchini ; Pedro Leopoldo Jerônimo Monteiro Junior ; Rodrigo Lemos Olivieri Rodrigues Alves ; Taynara Jaqueline Barreiro da Silva
Associated scholarship(s):23/02557-4 - Studies of ovarian and uterine physiology and improvement of assisted reproduction technologies to increase reproductive efficiency in cattle, BP.PD
21/09904-6 - Physiological and reproductive parameters of 14- to 16-month old Bos indicus heifers subjected to different circulating concentrations of progesterone and different ovulation induction protocols, BP.DR
22/00543-3 - Validation of a chemiluminescent immunoassay protocol for measuring circulating progesterone in cattle, BP.IC
+ associated scholarships 21/09924-7 - Effect of steroid hormones on the modulation of pituitary responsiveness and gonadotropin release in cattle, BP.DR
20/10659-3 - Studies of ovarian and uterine physiology and improvement of assisted reproductive technologies to elevate reproductive efficiency in cattle: hormone assays, BP.IC
19/26773-2 - Fertility of Nelore heifers submitted to FTAI protocols of 7 or 9 days, with PGF administered at different moments, BP.TT - associated scholarships


Experiments will be performed to better understand physiological aspects related to ovulation and maintenance of pregnancy in bovine females submitted to artificial insemination (AI) or embryo transfer (ET). In addition, studies will evaluate strategies to increase efficiency and/or simplify the use of fixed-time artificial insemination (FTAI) or embryo production protocols. Twenty-six experiments will be performed within six main themes, three of them about reproductive physiology (1 - Mechanisms involved in the maintenance of pregnancy; 2 - Ovarian, uterine and endocrine changes in response to different treatments or hormonal concentrations; 3 - Ovarian dynamics and embryo quality in FTAI protocols) and other three focused on reproductive biotechnologies (4 - Reproductive efficiency in Nelore cows and heifers submitted to FTAI protocols; 5 - Reproductive efficiency in dairy cows submitted to FTAI protocols; 6 - In vivo embryo production in superovulated cows inseminated with refrigerated sexed spermatozoa), in both beef cattle and dairy cattle. In these experiments, approximately 20,000 animals will be used. We will be performing sperm evaluations of the sires used, ovarian and transrectal uterine ultrasound examinations, blood sampling for hormone assays, and uterine flushings (when appropriate) to study ovarian and uterine dynamics and functions, embryo quality and fertility. (AU)

Articles published in Agência FAPESP Newsletter about the research grant:
Articles published in other media outlets (0 total):
More itemsLess items

Scientific publications (5)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
PRATA, ALEXANDRE B.; MADUREIRA, GUILHERME; ROBL, ADELINO J.; RIBEIRO, HEULLER S.; SAGAE, MILTON; ELIAS, V, MANOEL C.; PIMENTA, CESAR; BARRIOS, JHONNY; HARTMMAN, DIEGO; SCHNEIDER, ALTHUIR A.; et al. Progesterone-based timed AI protocols for Bos indicus cattle III: Comparison of protocol lengths. Theriogenology, v. 152, p. 29-35, . (18/03798-7)
MOTTA, JESSICA C. L.; MADUREIRA, GUILHERME; SILVA, LUCAS O.; ALVES, RODRIGO L. O. R.; SILVESTRI, MAYARA; DRUM, JESSICA N.; CONSENTINI, CARLOS E. C.; PRATA, ALEXANDRE B.; POHLER, KY G.; WILTBANK, MILO C.; et al. Interactions of circulating estradiol and progesterone on changes in endometrial area and pituitary responsiveness to GnRH. BIOLOGY OF REPRODUCTION, v. 103, n. 3, p. 643-653, . (18/03798-7, 17/16701-9, 18/09266-7)
CARDOSO CONSENTINI, CARLOS EDUARDO; WILTBANK, MILO CHARLES; SARTORI, ROBERTO. Factors That Optimize Reproductive Efficiency in Dairy Herds with an Emphasis on Timed Artificial Insemination Programs. ANIMALS, v. 11, n. 2, . (17/15904-3, 18/03798-7)
BASAVARAJA, RAGHAVENDRA; DRUM, JESSICA N.; SAPULENI, JACKSON; BIBI, LONICE; FRIEDLANDER, GILGI; KUMAR, SAI; SARTORI, ROBERTO; MEIDAN, RINA. Downregulated luteolytic pathways in the transcriptome of early pregnancy bovine corpus luteum are mimicked by interferon-tau in vitro. BMC Genomics, v. 22, n. 1, . (18/03798-7)
ALVES, RODRIGO L. O. R.; SILVA, MATEUS A.; CONSENTINI, CARLOS E. C.; SILVA, LUCAS O. E.; FOLCHINI, NATALIA P.; OLIVA, ABRAHAM L.; PRATA, ALEXANDRE B.; GONCALVES, JOSE RENATO S.; WILTBANK, MILO C.; SARTORI, ROBERTO. Hormonal combinations aiming to improve reproductive outcomes of Bos indicus cows submitted to estradiol/progesterone-based timed AI protocols. Theriogenology, v. 169, p. 89-99, . (18/03798-7, 18/14723-8)

Please report errors in scientific publications list by writing to: