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Scale-up of a pressurized liquid extraction equipment operating in batch - a study directed at efficient production of passion fruit tincture and soybean oil using green solvents

Grant number:18/18024-7
Support Opportunities:Regular Research Grants
Start date: March 01, 2019
End date: May 31, 2021
Field of knowledge:Agronomical Sciences - Food Science and Technology - Food Engineering
Principal Investigator:Alessandra Lopes de Oliveira
Grantee:Alessandra Lopes de Oliveira
Host Institution: Faculdade de Zootecnia e Engenharia de Alimentos (FZEA). Universidade de São Paulo (USP). Pirassununga , SP, Brazil
City of the host institution:Pirassununga
Associated researchers:Cintia Bernardo Gonçalves ; Fernando de Lima Caneppele ; Monica Roberta Mazalli

Abstract

This research project aims to construct an accelerated liquid extraction equipment in a pilot scale. The Accelerated Solvent Extraction (ASE) process is a new technique developed in the 1990s to prepare analytical samples, for example to more efficiently extract herbicide residues in soil and food. More recently, it has been used in the study of the composition of extracts from plant and animal sources.There are several process parameters considered in the extraction that occurs with the pressurized solvent, the pressure (which can range from 2 to 40 MPa), the temperature, the contact time between the solvent and the matrix in the fixed bed extractor, the quantity of solvent and the number of times that this solvent will contact the matrix in the extractor. The high pressure of the process enables a better diffusivity of the solvent in the matrix since at high pressure the solvent will remain in its liquid state in a temperature condition in which it would be in the vapor state at atmospheric pressure.In the study of these variables in the extraction process optimization performed by our research group, it was found that the fact of employing pressurized solvents in a batch system, there is considerable solvent economy; in addition, the process is relatively fast.The inclusion of the denomination "in batch" in this process is to differentiate it from the several semi-continuous processes that use pressurized solvents passing through the fixed bed packed with the matrix in a constant flow for a certain period, in this case it is not identified solvent economy. However, when operated in cycles, the pressurized liquid extraction equipment proposed in this project will subdivide the total amount of solvent to be employed by the number of cycles chosen and this implies the exhaustion of the compounds in the matrix with as little solvent as possible.When the equipment is assembled on a pilot scale, the process optimization tests will be carried out to obtain high yields of extracts using a low amount of solvents, paying attention to preserving the activity of the extract when the matrix is rich in active compounds.As will be seen in the introduction of this proposal, which defends the state of the art, the researchers involved in this project are knowledgeable about the subject and are constituents of the same research group newly created at the University of São Paulo.The development of a pilot-scale equipment implies the possibility of generating large amounts of studies, specifically for the implementation of this proposal, will be evaluated the solvent economy in obtaining soybean oil, product of commercial relevance in Brazil and obtaining extract of Passiflora incarnata L. also with important emphasis on national production. (AU)

Articles published in Agência FAPESP Newsletter about the research grant:
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Scientific publications (9)
(The scientific publications listed on this page originate from the Web of Science or SciELO databases. Their authors have cited FAPESP grant or fellowship project numbers awarded to Principal Investigators or Fellowship Recipients, whether or not they are among the authors. This information is collected automatically and retrieved directly from those bibliometric databases.)
RODRIGUES, LARISSA DA CUNHA; BODINI, RENATA BARBOSA; CANEPPELE, FERNANDO DE LIMA; DACANAL, GUSTAVO CESAR; CREVELIN, EDUARDO JOSE; DE MORAES, LUIZ ALBERTO BERALDO; DE OLIVEIRA, ALESSANDRA LOPES. Pressurized Liquid Extraction (PLE) in an Intermittent Process as an Alternative for Obtaining Passion Fruit (Passiflora edulis) Leaf Hydroalcoholic Extract (Tincture). PROCESSES, v. 11, n. 8, p. 23-pg., . (18/18024-7)
RODRIGUES, LARISSA DA CUNHA; DE CARVALHO, PEDRO IVO NUNES; DACANAL, GUSTAVO CESAR; DE OLIVEIRA, ALESSANDRA LOPES. Pressurized liquid extraction (PLE) in an intermittent process as a new alternative for production of tincture from medicinal plants: The scale up and economic evaluation for production of passion fruit ( Passiflora edulis Sims) leaf hydroalcoholic extract. FOOD AND BIOPRODUCTS PROCESSING, v. 149, p. 12-pg., . (18/18024-7)
RAMOS, PAULO RODOLFO; RODRIGUES, LARISSA DA CUNHA; ZABOT, GIOVANI LEONE; DE OLIVEIRA, ALESSANDRA LOPES. Extraction of Soybean Oil with Pressurized Ethanol: Prospects for a New Processing Approach with an Analysis of the Physical Properties of Crude Oil and Implementation Costs through Scale-Up in an Intermittent Process. PROCESSES, v. 12, n. 10, p. 21-pg., . (18/18024-7)
RAMOS, PAULO RODOLFO; SPONCHIADO, JOYCE; ECHENIQUE, JOAO VICTOR FEBRONIO; DACANAL, GUSTAVO CESAR; DE OLIVEIRA, ALESSANDRA LOPES. Kinetics of Vegetable Oils (Rice Bran, Sunflower Seed, and Soybean) Extracted by Pressurized Liquid Extraction in Intermittent Process. PROCESSES, v. 12, n. 6, p. 19-pg., . (22/02336-5, 18/18024-7)
VICENTINI-POLETTE, CAROLINA MEDEIROS; RAMOS, PAULO RODOLFO; GONCALVES, CINTIA BERNARDO; DE OLIVEIRA, ALESSANDRA LOPES. Determination of free fatty acids in crude vegetable oil samples obtained by high-pressure processes. FOOD CHEMISTRY-X, v. 12, . (18/18024-7)
RAMOS, PAULO RODOLFO; DE OLIVEIRA, ALESSANDRA LOPES; RAMOS, GISELLE VALLIM CORREA; KAMIMURA, ELIANA SETSUKO. Esterification Process in Supercritical Carbon Dioxide Catalyzed by Geotrichum candidum Lipase Produced with Mozzarella Cheese Whey and Corn Steep Liquor. PROCESSES, v. 12, n. 10, p. 16-pg., . (18/18024-7)
RAMOS, PAULO RODOLFO; VICENTINI-POLETTE, CAROLINA MEDEIROS; MAZALLI, MONICA ROBERTA; DE LIMA CANEPPELE, FERNANDO; DE OLIVEIRA, ALESSANDRA LOPES. Pressurized liquid extraction of soybean oil using intermittent process with ethanol and hexane as solvent: Extraction yield and physicochemical parameters comparison. JOURNAL OF FOOD PROCESS ENGINEERING, v. 47, n. 2, p. 19-pg., . (18/18024-7)
VICENTINI-POLETTE, CAROLINA MEDEIROS; YAMADA, BEATRIZ SATIE; RAMOS, PAULO RODOLFO; DA SILVA, MARTA GOMES; DE OLIVEIRA, ALESSANDRA LOPES. High Pressure Extraction as a Green Alternative to the Conventional Sunflower Oil (Helianthus annuus) Production Process - Extraction with Pressurized Ethanol in an Intermittent Process and with Supercritical Fluid. GLOBAL CHALLENGES, v. 8, n. 11, p. 17-pg., . (18/18024-7)
ECHENIQUE, JOAO VICTOR FEBRONIO; ALVAREZ-RIVERA, GERARDO; LUNA, VICTOR MANUEL AMADOR; ANTONIO, ANDRESSA FRANCIELLI VIEIRA DA CRUZ; MAZALLI, MONICA ROBERTA; IBANEZ, ELENA; CIFUENTES, ALEJANDRO; DE OLIVEIRA, ALESSANDRA LOPES. Pressurized liquid extraction with ethanol in an intermittent process for rice bran oil: Evaluation of process variables on the content of β-sitosterol and phenolic compounds, antioxidant capacity, acetylcholinesterase inhibitory activity, and oil quality. LWT-FOOD SCIENCE AND TECHNOLOGY, v. 207, p. 9-pg., . (22/02336-5, 18/18024-7)