Acute effects of walking exercise with self-selected intensity and performed until the maximum pain in pleasure and cerebral blood flow in patients with peripheral arterial disease

• Grant number: 18/00951-9
• Support Opportunities: Regular Research Grants
• Start date: July 01, 2019
• End date: December 31, 2022
• Field of knowledge: Health Sciences - Medicine - Surgery
• Principal Investigator: Raphael Mendes Ritti Dias
• Grantee: Raphael Mendes Ritti Dias
• Host Institution: Universidade Nove de Julho (UNINOVE). Campus Vergueiro. São Paulo , SP, Brazil
• Associated researchers: Alexandre Hideki Okano ; Gabriel Grizzo Cucato ; Marilia de Almeida Correia ; Nelson Wolosker
• Associated research grant(s): 22/16424-3 - 28th Annual Congress of the European Congress of Sport Science, AR.EXT

Abstract

Although the benefits of walking exercises for patients with peripheral arterial disease (PAD) and symptoms of claudication are well established, one of the main problems encountered in this type of protocol is the low adherence to training, which is possibly related to the recommendation for exercise with maximum pain. Exercises with self-selected intensity have emerged as an alternative to the usual training prescriptions, since their use seems to increase pleasure during exercise. However, this prescription was not used previously in patients with PAD. Understanding how this type of exercise can affect physiological demands, pleasure, and metabolism during exercise is the first step toward its possible use. Thus, the aim of this study will be to analyse the acute effects of exercise with self-selected intensity and until maximal pain on cerebral perfusion and pleasure sensations in patients with PAD. Seventeen patients with PAD will be submitted to three experimental sessions: exercise with self-selected intensity, exercise until maximal pain and control. During the sessions, volume and intensity (duration and velocity) of the exercise performed, affective responses and cerebral perfusion will be obtained. The responses and comparisons among the three sessions will be analyzed through the two-way ANOVA and the Newman-Keuls post-hoc test. The value of P <0.05 will be considered significant. (AU)