Protein profile and milk proteome with contrasting genotypes for the ²-casein gene and verification of the proteolytic action of Bacillus cereus s.s. and Pseudomonas fluorescens and technological treatments applied to milk on the production of BCM7

• Grant number: 19/09583-5
• Support Opportunities: Regular Research Grants
• Start date: October 01, 2019
• End date: September 30, 2021
• Field of knowledge: Agronomical Sciences - Veterinary Medicine - Products of Animal Origin Inspection
• Principal Investigator: Ana Maria Centola Vidal
• Grantee: Ana Maria Centola Vidal
• Host Institution: Faculdade de Zootecnia e Engenharia de Alimentos (FZEA). Universidade de São Paulo (USP). Pirassununga , SP, Brazil
• City of the host institution: Pirassununga
• Associated researchers: Arlindo Saran Netto ; Júlio Cesar de Carvalho Balieiro ; Mirele Daiana Poleti

Abstract

Little is known about the phenotypic characteristics and physical-chemical properties caused by the different genotypes in the milk produced and what may have led to the choice between alleles A1 and A2 for dairy cattle. There are also no reports to date on the performance of microbial proteases in milk produced by animals with the A2A2 genotype. The scientific community still does not fully agree on the benefits of consumption of A2 milk compared to A1, and considering the new demands of the consumer market, which are increasingly related to the quality of nutrients, especially protein and fat, and to the the identification and quantification of BCM-7 will pave the way for this demand and will serve as a basis for other studies in the area. The present project aims to evaluate the protein and proteome profile of milk with contrasting genotypes for the ²-casein gene and to verify the proteolytic action of Bacillus cereus ss and Pseudomonas fluorescens and technological treatments applied to milk on BCM-7 production. (AU)

Scientific publications

(The scientific publications listed on this page originate from the Web of Science or SciELO databases. Their authors have cited FAPESP grant or fellowship project numbers awarded to Principal Investigators or Fellowship Recipients, whether or not they are among the authors. This information is collected automatically and retrieved directly from those bibliometric databases.)

VASCONCELLOS, ALENIA NALIATO; SANTOS, ARTHUR FIRMINO DE MACEDO; VAZ, ANDREIA CRISTINA NAKASHIMA; DA FONSECA, DANIELLE DE CASSIA MARTINS; DA CRUZ, MARCIA DELGADO; MARINO, ELIZANGELA DOMENIS; OLIVEIRA, LUISA MARIA FERREIRA DE SOUSA; CHEQUER, THAIS NALIATO; VIDAL, ANA MARIA CENTOLA. Susceptibility of κ-Casein to degradation by microbial proteases in experimentally contaminated milk from cows with different β-Casein genotypes. INTERNATIONAL DAIRY JOURNAL, v. 169, p. 6-pg., 2025-10-01. (19/09583-5)

MARINO, E. D.; FONSECA, D. C. M.; VASCONCELLOS, A. N.; OLIVEIRA, L. M. F. S.; SANTOS, A. F. M.; BALIEIRO, J. C. C.; VIDAL, A. M. C.. Effect of A1 and A2 alleles of CSN2 gene on yield, composition traits, and somatic cell count of milk from cows of contrasting genotypes in Brazil. Genetics and Molecular Research, v. 23, n. 4, p. 12-pg., 2024-09-23. (19/09583-5, 19/11585-6)