Modelling the dengue hemorrhagic fever

• Grant number: 19/23202-4
• Support Opportunities: Research Grants - Visiting Researcher Grant - International
• Start date: December 07, 2019
• End date: December 20, 2019
• Field of knowledge: Physical Sciences and Mathematics - Mathematics - Applied Mathematics
• Principal Investigator: Cláudia Pio Ferreira
• Grantee: Cláudia Pio Ferreira
• Visiting researcher: Maria de Lourdes Esteva
• Visiting researcher institution: Universidad Nacional Autónoma de México (UNAM) , Mexico
• Host Institution: Instituto de Biociências (IBB). Universidade Estadual Paulista (UNESP). Campus de Botucatu. Botucatu , SP, Brazil
• City of the host institution: Botucatu

Abstract

A mathematical model will be set up to describe the temporal evolution of dengue virus and human immune system during a second infection. The hypothesis is that specific and non-especific immunological cells compete by virus neutralization. The goal is to analyse two situation: when the infection is controlled by the immune system; and when the infection is enhanced by the immune cells generated after a primary response with a different virus. (AU)

Scientific publications

(The scientific publications listed on this page originate from the Web of Science or SciELO databases. Their authors have cited FAPESP grant or fellowship project numbers awarded to Principal Investigators or Fellowship Recipients, whether or not they are among the authors. This information is collected automatically and retrieved directly from those bibliometric databases.)

CAMARGO, FELIPE DE A.; ADIMY, MOSTAFA; ESTEVA, LOURDES; METAYER, CLEMENCE; FERREIRA, CLAUDIA P.. Modeling the Relationship Between Antibody-Dependent Enhancement and Disease Severity in Secondary Dengue Infection. Bulletin of Mathematical Biology, v. 83, n. 8, AUG 2021. (19/22157-5, 19/23202-4)