| Grant number: | 19/22157-5 |
| Support type: | Regular Research Grants |
| Duration: | March 01, 2020 - February 28, 2022 |
| Field of knowledge: | Physical Sciences and Mathematics - Mathematics - Applied Mathematics |
| Cooperation agreement: | INRIA |
| Mobility Program: | SPRINT - Projetos de pesquisa - Mobilidade |
| Principal researcher: | Cláudia Pio Ferreira |
| Grantee: | Cláudia Pio Ferreira |
| Principal researcher abroad: | Pierre-Alexandre Jacques Bliman |
| Institution abroad: | Institut National de Recherche en Informatique et en Automatique (INRIA Paris), France |
| Home Institution: | Instituto de Biociências (IBB). Universidade Estadual Paulista (UNESP). Campus de Botucatu. Botucatu , SP, Brazil |
| Assoc. researchers: | Abderrahman Iggidr ; Luis Manuel Lopes Neves de Almeida ; Mostafa Adimy ; Renato Mendes Coutinho ; Roberto André Kraenkel ; Sergio Muniz Oliva Filho |
| Associated research grant: | 18/24058-1 - Arboviroses: dynamics and vector control, AP.R |
Abstract
Taking into account all the infectious disease spread worldwide, vector-borne diseases account for over 17%. For a huge part of them, no efficient vaccine is available, and control efforts must be done on the vector population. Focusing on dengue and malaria, two diseases transmitted by vector mosquito and which cause high morbidity and mortality around the world, this project aims to model disease transmission, its spread and control, in a context of climatic and environmental change. For this, the main drives of disease transmission will be addressed to understand which factors modulate the spatio-temporal patterns observed, especially in Brazil. Combining techniques of data analysis with mathematical models and control theory, the plan is to work on data analysis to define potential biotic and abiotic factors that drives malaria and dengue disease dynamics; to study and model the effects of seasonality on the spread of the diseases; to understand spatial aspects of the transmission through the setup of models capable to account for nonlocal and heterogeneous aspect; and to analyse alternative approaches of mosquito control, especially the biological control methods based on sterile mosquitoes or on infection by bacterium that reduces the vectorial capacity. (AU)