Research through images from high field magnetic resonance aimed at studies in humans

• Grant number: 05/56447-7
• Support type: Inter-institutional Cooperation in Support of Brain Research (CINAPCE) - Thematic Grants
• Duration: April 01, 2007 - March 31, 2015
• Field of knowledge: Health Sciences - Medicine - Medical Clinics
• Principal Investigator: João Pereira Leite
• Grantee: João Pereira Leite
• Home Institution: Faculdade de Medicina de Ribeirão Preto (FMRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
• Co-Principal Investigators: Americo Ceiki Sakamoto ; Antonio Carlos dos Santos ; Norberto Garcia Cairasco
• Associated grant(s): 12/01413-4 - ASNR 50th Annual Meeting & The Foundation of the ASNR Symposium 2012, AR.EXT; 06/58089-3 - Differential expression of heat shock proteins in temporal lobe epilepsy with and without psychiatric comorbidities, AR.EXT
• Associated scholarship(s): 12/14152-4 - Prognostic contribution of subtraction between ictal and interictal SPECT and its alignment to MRI (SISCOM) in patients with pharmacoresistant epilepsy associated to normal 3T MRI, BP.DD; 11/10898-9 - Characterization of behavior, eletrographic and molecular changes during and after spontaneous recurrent seizures in the temporal lobe epilepsy model chronic phase induced by continuous electrical perforant path stimulation, BP.DR; 11/10809-6 - Sonothrombolysis by focused and modulated acoustic radiation force using double beam, BP.DR; + associated scholarships 10/04616-8 - Validation of the Subtraction of the ictal and interictal SPECTs aligned with Magnetic Resonance in the localization of the Epileptogenic Zone in pacients with pharmacoresistant frontal lobe epilepsy., BP.MS; 09/00269-4 - Methods of electrical sources imaging from EEG and fMRI data., BP.IC; 08/02979-6 - Implications of extrahippocampal and extratemporal changes in control of seizures and the result of surgery in patients with temporal lobe epilepsy, BP.DR - associated scholarships

Abstract

This proposal aims to establish a base for one of the MRCs attached to the ClnAPCe program for studies in humans having as their base neuroimaging techniques of high field MR. The proposing group will be responsible for the carrying out of experimental studies and in patients with untreatable epilepsy, as well as developing new software and protocols for structural and functional MRI studies. This center brings together groups from different departments, among them from Physics and Mathematics, from Clinical Medicine, from Neurology, from Neurosurgery, from Physiology, Pathology and Molecular Biology. We will develop research activities in MRI, adding different aspects of epilepsy, ranging from neurophysiological questions to applications of new diagnostic and prognostic methodologies. This proposal, in addition to being multidisciplinary, is also multicenter. For example, neuropathological studies will be conducted by researchers from two of the proposing centers, USP-RP and UNICAMP. Furthermore, projects involving animal experimentation will be carried out in collaboration with USP - São Carlos. (AU)

Scientific publications

(53)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

TOTOLA, LEONARDO T.; MALHEIROS-LIMA, MILENE R.; DELFINO-PEREIRA, POLIANNA; DEL VECCHIO, FLAVIO; SOUZA, FELIPE C.; TAKAKURA, ANA C.; GARCIA-CAIRASCO, NORBERTO; MOREIRA, THIAGO S. Amygdala rapid kindling impairs breathing in response to chemoreflex activation. Brain Research, v. 1718, p. 159-168, SEP 1 2019. Web of Science Citations: 1.

RODRIGO ANTONIO PESSINI; ANTONIO CARLOS DOS SANTOS; CARLOS ERNESTO GARRIDO SALMON. Quantitative MRI data in Multiple Sclerosis patients: a pattern recognition study. Res. Biomed. Eng., v. 34, n. 2, p. -, Jun. 2018.

RUGGIERO, RAFAEL N.; ROSSIGNOLI, MATHEUS T.; LOPES-AGUIAR, CLEITON; LEITE, JOAO P.; BUENO-JUNIOR, LEZIO S.; ROMCY-PEREIRA, RODRIGO N. Lithium modulates the muscarinic facilitation of synaptic plasticity and theta-gamma coupling in the hippocampal-prefrontal pathway. Experimental Neurology, v. 304, p. 90-101, JUN 2018. Web of Science Citations: 1.

DELFINO-PEREIRA, POLIANNA; BERTTI-DUTRA, POLIANA; DE LIMA UMEOKA, EDUARDO HENRIQUE; CORTES DE OLIVEIRA, JOSE ANTONIO; SANTOS, VICTOR RODRIGUES; FERNANDES, ARTUR; MARRONI, SIMONE SALDANHA; DEL VECCHIO, FLAVIO; GARCIA-CAIRASCO, NORBERTO. Intense olfactory stimulation blocks seizures in an experimental model of epilepsy. Epilepsy & Behavior, v. 79, p. 213-224, FEB 2018. Web of Science Citations: 0.

Quantitative MRI data in Multiple Sclerosis patients: a pattern recognition study. Res. Biomed. Eng., n. ahead, p. -, 2018.

RODRIGUES, FERNANDA LUCIANO; FAIS, RAFAEL S.; PEREIRA, MARLIA G. A. G.; GARCIA-CAIRASCO, NORBERTO; TOSTES, RITA C.; CARNEIRO, FERNANDO S. Erectile Dysfunction in Wistar Audiogenic Rats Is Associated With Increased Cavernosal Contraction and Decreased Neuronal Nitric Oxide Synthase Protein Expression. UROLOGY, v. 106, AUG 2017. Web of Science Citations: 0.

SANCHEZ-BENITO, DAVID; GOMEZ-NIETO, RICARDO; HERNANDEZ-NORIEGA, SONIA; BATISTA MURASHIMA, ADRIANA ANDRADE; CORTES DE OLIVEIRA, JOSE ANTONIO; GARCIA-CAIRASCO, NORBERTO; LOPEZ, DOLORES E.; HYPPOLITO, MIGUEL ANGELO. Morphofunctional alterations in the olivocochlear efferent system of the genetic audiogenic seizure-prone hamster GASH:Sal. Epilepsy & Behavior, v. 71, n. B, p. 193-206, JUN 2017. Web of Science Citations: 3.

TOTOLA, LEONARDO T.; TAKAKURA, ANA C.; OLIVEIRA, JOSE ANTONIO C.; GARCIA-CAIRASCO, NORBERTO; MOREIRA, THIAGO S. Impaired central respiratory chemoreflex in an experimental genetic model of epilepsy. JOURNAL OF PHYSIOLOGY-LONDON, v. 595, n. 3, p. 983-999, FEB 2017. Web of Science Citations: 10.

BERNARDES DA SILVA FILHO, SILVIO RAMOS; OLIVEIRA BARBOSA, JEAM HAROLDO; RONDINONI, CARLO; DOS SANTOS, ANTONIO CARLOS; GARRIDO SALMON, CARLOS ERNESTO; DA COSTA LIMA, NEREIDA KILZA; FERRIOLLI, EDUARDO; MORIGUTI, JULIO CESAR. Neuro-degeneration profile of Alzheimer's patients: A brain morphometry study. NEUROIMAGE-CLINICAL, v. 15, p. 15-24, 2017. Web of Science Citations: 9.

DO VAL-DA SILVA, RAQUEL ARAUJO; PEIXOTO-SANTOS, JOSE EDUARDO; SCANDIUZZI, RENATA CALDO; BALISTA, PRISCILA ALVES; BASSI, MIRIAN; GLASS, MOGENS LESNER; ROMCY-PEREIRA, RODRIGO NEVES; GALVIS-ALONSA, ORFA YINETH; LEITEA, JOAO PEREIRA. DECREASED NEURON LOSS AND MEMORY DYSFUNCTION IN PILOCARPINE-TREATED RATS PRE-EXPOSED TO HYPOXIA. Neuroscience, v. 332, p. 88-100, SEP 22 2016. Web of Science Citations: 3.

GRANJEIRO, ERICA MARIA; DA SILVA, GLAUBER S. F.; GIUSTI, HUMBERTO; OLIVEIRA, JOSE ANTONIO; GLASS, MOGENS LESNER; GARCIA-CAIRASCO, NORBERTO. Behavioral, Ventilatory and Thermoregulatory Responses to Hypercapnia and Hypoxia in the Wistar Audiogenic Rat (WAR) Strain. PLoS One, v. 11, n. 5 MAY 5 2016. Web of Science Citations: 5.

DALPIAN, FRANCINE; BRUSCO, JANAINA; CALCAGNOTTO, MARIA ELISA; MOREIRA, JORGE E.; RASIA-FILHO, ALBERTO A. Distribution of glutamate receptors in the posterodorsal medial amygdala of adult male rats. HISTOLOGY AND HISTOPATHOLOGY, v. 30, n. 11, p. 1303-1311, NOV 2015. Web of Science Citations: 6.

PEIXOTO-SANTOS, JOSE EDUARDO; VELASCO, TONICARLO RODRIGUES; GALVIS-ALONSO, ORFA YINETH; ARAUJO, DAVID; KANDRATAVICIUS, LUDMYLA; ASSIRATI, JOAO ALBERTO; CARLOTTI, CARLOS GILBERTO; SCANDIUZZI, RENATA CALDO; DOS SANTOS, ANTONIO CARLOS; LEITE, JOAO PEREIRA. Temporal lobe epilepsy patients with severe hippocampal neuron loss but normal hippocampal volume: Extracellular matrix molecules are important for the maintenance of hippocampal volume. Epilepsia, v. 56, n. 10, p. 1562-1570, OCT 2015. Web of Science Citations: 14.

FAZAN, JR., RUBENS; SILVA, CARLOS ALBERTO A.; CORTES OLIVEIRA, JOSE ANTONIO; SALGADO, HELIO CESAR; MONTANO, NICOLA; GARCIA-CAIRASCO, NORBERTO. Evaluation of Cardiovascular Risk Factors in the Wistar Audiogenic Rat (WAR) Strain. PLoS One, v. 10, n. 6 JUN 1 2015. Web of Science Citations: 8.

OLIVEIRA BARBOSA, JEAM HAROLDO; SANTOS, ANTONIO CARLOS; TUMAS, VITOR; LIU, MANJU; ZHENG, WEILI; HAACKE, E. MARK; GARRIDO SALMON, CARLOS ERNESTO. Quantifying brain iron deposition in patients with Parkinson's disease using quantitative susceptibility mapping, R2 and R2. MAGNETIC RESONANCE IMAGING, v. 33, n. 5, p. 559-565, JUN 2015. Web of Science Citations: 86.

KANDRATAVICIUS, LUDMYLA; BALISTA, PRISCILA ALVES; WOLF, DANIELE CRISTINA; ABRAO, JOAO; EVORA, PAULO ROBERTO; RODRIGUES, ALFREDO JOSE; CHAVES, CRISTIANO; MAIA-DE-OLIVEIRA, JOAO PAULO; LEITE, JOAO PEREIRA; DURSUN, SERDAR MURAT; BAKER, GLEN BRYAN; GUIMARAES, FRANCISCO SILVEIRA; CECILIO HALLAK, JAIME EDUARDO. Effects of nitric oxide-related compounds in the acute ketamine animal model of schizophrenia. BMC NEUROSCIENCE, v. 16, MAR 7 2015. Web of Science Citations: 17.

KANDRATAVICIUS, LUDMYLA; PEIXOTO-SANTOS, JOSE EDUARDO; MONTEIRO, MARIANA RAQUEL; SCANDIUZZI, RENATA CALDO; CARLOTTI, JR., CARLOS GILBERTO; ASSIRATI, JR., JOAO ALBERTO; HALLAK, JAIME EDUARDO; LEITE, JOAO PEREIRA. Mesial temporal lobe epilepsy with psychiatric comorbidities: a place for differential neuroinflammatory interplay. JOURNAL OF NEUROINFLAMMATION, v. 12, FEB 25 2015. Web of Science Citations: 15.

KANDRATAVICIUS, LUDMYLA; HALLAK, JAIME E.; CARLOTTI, JR., CARLOS G.; ASSIRATI, JR., JOAO A.; LEITE, JOAO P. Hippocampal expression of heat shock proteins in mesial temporal lobe epilepsy with psychiatric comorbidities and their relation to seizure outcome. Epilepsia, v. 55, n. 11, p. 1834-1843, NOV 2014. Web of Science Citations: 15.

BERTTI, POLIANA; TEJADA, JULIAN; PINHEIRO MARTINS, ANA PAULA; CLETO DAL-COL, MARIA LUIZA; TERRA, VERA CRISTINA; CORTES DE OLIVEIRA, JOSE ANTONIO; VELASCO, TONICARLO RODRIGUES; SAKAMOTO, AMERICO CEIKI; GARCIA-CAIRASCO, NORBERTO. Looking for complexity in quantitative semiology of frontal and temporal lobe seizures using neuroethology and graph theory. Epilepsy & Behavior, v. 38, n. SI, p. 81-93, SEP 2014. Web of Science Citations: 2.

KANDRATAVICIUS, LUDMYLA; HALLAK, JAIME EDUARDO; LEITE, JOAO PEREIRA. What are the similarities and differences between schizophrenia and schizophrenia-like psychosis of epilepsy? A neuropathological approach to the understanding of schizophrenia spectrum and epilepsy. Epilepsy & Behavior, v. 38, n. SI, p. 143-147, SEP 2014. Web of Science Citations: 5.

GRANJEIRO, ERICA MARIA; MARRONI, SIMONE SALDANHA; MARTINS DIAS, DANIEL PENTEADO; HECK BONAGAMBA, LENI GOMES; COSTA, KAUE MACHADO; DOS SANTOS, JESSICA CRISTINA; CORTES OLIVEIRA, JOSE ANTONIO; MACHADO, BENEDITO H.; GARCIA-CAIRASCO, NORBERTO. Behavioral and Cardiorespiratory Responses to Bilateral Microinjections of Oxytocin into the Central Nucleus of Amygdala of Wistar Rats, an Experimental Model of Compulsion. PLoS One, v. 9, n. 7 JUL 18 2014. Web of Science Citations: 4.

BRUSCO, JANAINA; MERLO, SUELEN; IKEDA, ERIKA T.; PETRALIA, RONALD S.; KACHAR, BECHARA; RASIA-FILHO, ALBERTO A.; MOREIRA, JORGE E. Inhibitory and Multisynaptic Spines, and Hemispherical Synaptic Specialization in the Posterodorsal Medial Amygdala of Male and Female Rats. JOURNAL OF COMPARATIVE NEUROLOGY, v. 522, n. 9, p. 2075-2088, JUN 15 2014. Web of Science Citations: 17.

KANDRATAVICIUS, LUDMYLA; HALLAK, JAIME EDUARDO; CARLOTTI, JR., CARLOS GILBERTO; ASSIRATI, JR., JOAO ALBERTO; LEITE, JOAO PEREIRA. Neurotrophin receptors expression in mesial temporal lobe epilepsy with and without psychiatric comorbidities and their relation with seizure type and surgical outcome. ACTA NEUROPATHOLOGICA COMMUNICATIONS, v. 2, 2014. Web of Science Citations: 9.

KANDRATAVICIUS, LUDMYLA; BALISTA, PRISCILA ALVES; LOPES-AGUIAR, CLEITON; RUGGIERO, RAFAEL NAIME; UMEOKA, EDUARDO HENRIQUE; GARCIA-CAIRASCO, NORBERTO; BUENO-JUNIOR, LEZIO SOARES; LEITE, JOAO PEREIRA. Animal models of epilepsy: use and limitations. NEUROPSYCHIATRIC DISEASE AND TREATMENT, v. 10, p. 1693-1705, 2014. Web of Science Citations: 103.

KANDRATAVICIUS, LUDMYLA; ROSA-NETO, PEDRO; MONTEIRO, MARIANA RAQUEL; GUIOT, MARIE-CHRISTINE; ASSIRATI, JR., JOAO ALBERTO; CARLOTTI, JR., CARLOS GILBERTO; KOBAYASHI, ELIANE; LEITE, JOAO PEREIRA. Distinct Increased Metabotropic Glutamate Receptor Type 5 (mGluR5) in Temporal Lobe Epilepsy With and Without Hippocampal Sclerosis. HIPPOCAMPUS, v. 23, n. 12, p. 1212-1230, DEC 2013. Web of Science Citations: 23.

PEREIRA, MARILIA G. A. G.; SOUZA, LAURA L.; BECARI, CHRISTIANE; DUARTE, DIEGO A.; CAMACHO, FABIO R. B.; OLIVEIRA, JOSE ANTONIO C.; GOMES, MARCELO D.; OLIVEIRA, EDUARDO B.; SALGADO, MARIA CRISTINA O.; GARCIA-CAIRASCO, NORBERTO; COSTA-NETO, CLAUDIO M. Angiotensin II-Independent Angiotensin-(1-7) Formation in Rat Hippocampus Involvement of Thimet Oligopeptidase. Hypertension, v. 62, n. 5, p. 879-885, NOV 2013. Web of Science Citations: 14.

LOPES-AGUIAR, CLEITON; BUENO-JUNIOR, LEZIO SOARES; RUGGIERO, RAFAEL NAIME; ROMCY-PEREIRA, RODRIGO NEVES; LEITE, JOAO PEREIRA. NMDA receptor blockade impairs the muscarinic conversion of sub-threshold transient depression into long-lasting LTD in the hippocampus-prefrontal cortex pathway in vivo: Correlation with gamma oscillations. Neuropharmacology, v. 65, p. 143-155, FEB 2013. Web of Science Citations: 10.

KANDRATAVICIUS, LUDMYLA; MONTEIRO, MARIANA RAQUEL; HALLAK, JAIME EDUARDO; CARLOTTI, JR., CARLOS GILBERTO; ASSIRATI, JR., JOAO ALBERTO; LEITE, JOAO PEREIRA. Microtubule-Associated Proteins in Mesial Temporal Lobe Epilepsy with and without Psychiatric Comorbidities and Their Relation with Granular Cell Layer Dispersion. BIOMED RESEARCH INTERNATIONAL, 2013. Web of Science Citations: 15.

RONDINONI, C.; AMARO, JR., E.; CENDES, F.; DOS SANTOS, A. C.; SALMON, C. E. G. Effect of scanner acoustic background noise on strict resting-state fMRI. Brazilian Journal of Medical and Biological Research, v. 46, n. 4, p. 359-367, Abr. 2013. Web of Science Citations: 12.

BUENO-JUNIOR, LEZIO SOARES; LOPES-AGUIAR, CLEITON; RUGGIERO, RAFAEL NAIME; ROMCY-PEREIRA, RODRIGO NEVES; LEITE, JOAO PEREIRA. Muscarinic and Nicotinic Modulation of Thalamo-Prefrontal Cortex Synaptic Pasticity In Vivo. PLoS One, v. 7, n. 10 OCT 30 2012. Web of Science Citations: 16.

PEIXOTO-SANTOS, JOSE EDUARDO; GALVIS-ALONSO, ORFA YINETH; VELASCO, TONICARLO RODRIGUES; KANDRATAVICIUS, LUDMYLA; ASSIRATI, JOAO ALBERTO; CARLOTTI, CARLOS GILBERTO; SCANDIUZZI, RENATA CALDO; SERAFINI, LUCIANO NEDER; LEITE, JOAO PEREIRA. Increased Metallothionein I/II Expression in Patients with Temporal Lobe Epilepsy. PLoS One, v. 7, n. 9 SEP 18 2012. Web of Science Citations: 17.

ROSSETTI, FRANCO; ARAUJO RODRIGUES, MARCELO CAIRRAO; MARRONI, SIMONE S.; FERNANDES, ARTUR; FORESTI, MAIRA LICIA; ROMCY-PEREIRA, RODRIGO N.; DE ARAUJO, DRAULIO BARROS; GARCIA-CAIRASCO, NORBERTO. Behavioral and EEG effects of GABAergic manipulation of the nigro-tectal pathway in the Wistar audiogenic rat (WAR) strain II: An EEG wavelet analysis and retrograde neuronal tracer approach. Epilepsy & Behavior, v. 24, n. 4, p. 391-398, AUG 2012. Web of Science Citations: 7.

JOSÉ EDUARDO PEIXOTO-SANTOS; ORFA YINETH GALVIS-ALONSO; TONICARLO R. VELASCO; LUDMYLA KANDRATAVICIUS; JOÃO ALBERTO ASSIRATI JR; CARLOS GILBERTO CARLOTTI; RENATA CALDO SCANDIUZZI; LUCIANO NEDER SERAFINI; JOÃO PEREIRA LEITE. Different levels of MT-I/II between patients with MTLE with or without seizure generalization: does hippocampal MT-I/II affects seizure spread, or does seizure spread promotes differential expression of MT-I/II?. Journal of Epilepsy and Clinical Neurophysiology, v. 18, n. 1, p. 16-20, Mar. 2012.

KANDRATAVICIUS, LUDMYLA; HALLAK, JAIME EDUARDO; YOUNG, LIONEL TREVOR; ASSIRATI, JOAO ALBERTO; CARLOTTI, JR., CARLOS GILBERTO; LEITE, JOAO PEREIRA. Differential aberrant sprouting in temporal lobe epilepsy with psychiatric co-morbidities. PSYCHIATRY RESEARCH, v. 195, n. 3, p. 144-150, FEB 28 2012. Web of Science Citations: 17.

FAZAN, JR., RUBENS; DE OLIVEIRA, MAURO; OLIVEIRA, JOSE ANTONIO C.; SALGADO, HELIO C.; GARCIA-CAIRASCO, NORBERTO. Changes in autonomic control of the cardiovascular system in the Wistar audiogenic rat (WAR) strain. Epilepsy & Behavior, v. 22, n. 4, p. 666-670, DEC 2011. Web of Science Citations: 15.

DINIZ, P. R. B.; VELASCO, T. R.; SALMON, C. E. G.; SAKAMOTO, A. C.; LEITE, J. P.; SANTOS, A. C. Extratemporal Damage in Temporal Lobe Epilepsy: Magnetization Transfer Adds Information to Volumetric MR Imaging. AMERICAN JOURNAL OF NEURORADIOLOGY, v. 32, n. 10, p. 1857-1861, NOV 2011. Web of Science Citations: 10.

ROSSETTI, FRANCO; ARAUJO RODRIGUES, MARCELO CAIRRAO; CORTES DE OLIVEIRA, JOSE ANTONIO; GARCIA-CAIRASCO, NORBERTO. Behavioral and EEG effects of GABAergic manipulation of the nigrotectal pathway in the Wistar audiogenic rat strain. Epilepsy & Behavior, v. 22, n. 2, p. 191-199, OCT 2011. Web of Science Citations: 8.

CASTRO, O. W.; FURTADO, M. A.; TILELLI, C. Q.; FERNANDES, A.; PAJOLLA, G. P.; GARCIA-CAIRASCO, N. Comparative neuroanatomical and temporal characterization of FluoroJade-positive neurodegeneration after status epilepticus induced by systemic and intrahippocampal pilocarpine in Wistar rats. Brain Research, v. 1374, p. 43-55, FEB 16 2011. Web of Science Citations: 36.

GOES GITAI, DANIEL LEITE; FACHIN, ANA LUCIA; MELLO, STEPHANO SPANO; ELIAS, CAROL FUZACHI; BITTENCOURT, JACKSON CIONI; LEITE, JOAO PEREIRA; DA SILVA PASSOS, GERALDO ALEIXO; GARCIA-CAIRASCO, NORBERTO; PACO-LARSON, MARIA LUISA. The non-coding RNA BC1 is down-regulated in the hippocampus of Wistar Audiogenic Rat (WAR) strain after audiogenic kindling. Brain Research, v. 1367, p. 114-121, JAN 7 2011. Web of Science Citations: 11.

MEJIA, J.; GALVIS-ALONSO, O. Y.; DE CASTRO, A. A.; BRAGA, J.; LEITE, J. P.; SIMOES, M. V. A clinical gamma camera-based pinhole collimated system for high resolution small animal SPECT imaging. Brazilian Journal of Medical and Biological Research, v. 43, n. 12, p. 1160-1166, DEC 2010. Web of Science Citations: 12.

PEREIRA, MARILIA G. A. G.; BECARI, CHRISTIANE; OLIVEIRA, JOSE A. C.; SALGADO, MARIA CRISTINA O.; GARCIA-CAIRASCO, NORBERTO; COSTA-NETO, CLAUDIO M. Inhibition of the renin-angiotensin system prevents seizures in a rat model of epilepsy. Clinical Science, v. 119, n. 11-12, p. 477-482, DEC 2010. Web of Science Citations: 38.

DALL'OGLIO, ALINE; FERME, DENISE; BRUSCO, JANAINA; MOREIRA, JORGE E.; RASIA-FILHO, ALBERTO A. The ``single-section{''} Golgi method adapted for formalin-fixed human brain and light microscopy. JOURNAL OF NEUROSCIENCE METHODS, v. 189, n. 1, p. 51-55, MAY 30 2010. Web of Science Citations: 11.

GITAÍ‚ D.L.G.; MARTINELLI‚ H.N.; VALENTE‚ V.; PEREIRA‚ M.G.; OLIVEIRA‚ J.A.C.; ELIAS‚ C.F.; BITTENCOURT‚ J.C.; LEITE‚ J.P.; COSTA-NETO‚ C.M.; GARCIA-CAIRASCO‚ N.; OTHERS. Increased expression of GluR2-flip in the hippocampus of the Wistar audiogenic rat strain after acute and kindled seizures. HIPPOCAMPUS, v. 20, n. 1, p. 125-133, 2010.

BURITICA, EFRAIN; VILLAMIL, LILIANA; GUZMAN, FRANCISCO; ESCOBAR, MARTHA I.; GARCIA-CAIRASCO, NORBERTO; PIMIENTA, HEMAN J. Changes in Calcium-Binding Protein Expression in Human Cortical Contusion Tissue. JOURNAL OF NEUROTRAUMA, v. 26, n. 12, p. 2145-2155, DEC 2009. Web of Science Citations: 20.

DORETTO, MARIA C.; CORTES-DE-OLIVEIRA, JOSE A.; ROSSETTI, FRANCO; GARCIA-CAIRASCO, NORBERTO. Role of the superior colliculus in the expression of acute and kindled audiogenic seizures in Wistar audiogenic rats. Epilepsia, v. 50, n. 12, p. 2563-2574, DEC 2009. Web of Science Citations: 11.

MEJIA, J.; GALVIS-ALONSO, O. Y.; BRAGA, J.; CORREA, R.; LEITE, J. P.; SIMOES, M. V. Methodological approaches to planar and volumetric scintigraphic imaging of small volume targets with high spatial resolution and sensitivity. Brazilian Journal of Medical and Biological Research, v. 42, n. 8, p. 692-699, AUG 2009. Web of Science Citations: 5.

ARAUJO GUEDES, RUBEM CARLOS; CORTES DE OLIVEIRA, JOSE ANTONIO; AMANCIO-DOS-SANTOS, ANGELA; GARCIA-CAIRASCO, NORBERTO. Sexual differentiation of cortical spreading depression propagation after acute and kindled audiogenic seizures in the Wistar audiogenic rat (WAR). Epilepsy Research, v. 83, n. 2-3, p. 207-214, FEB 2009. Web of Science Citations: 22.

N. GARCIA-CAIRASCO. Learning about brain physiology and complexity from the study of the epilepsies. Brazilian Journal of Medical and Biological Research, v. 42, n. 1, p. 76-86, Jan. 2009.

MATHERN‚ G.W.; ANDRES‚ M.; SALAMON‚ N.; CHANDRA‚ P.S.; ANDRE‚ V.M.; CEPEDA‚ C.; LEVINE‚ M.S.; LEITE‚ J.P.; NEDER‚ L.; VINTERS‚ H.V. A hypothesis regarding the pathogenesis and epileptogenesis of pediatric cortical dysplasia and hemimegalencephaly based on MRI cerebral volumes and NeuN cortical cell densities. Epilepsia, v. 48, n. s5, p. 74-78, 2007.

FLÁVIA ARAUJO GUEDES; ORFA YINETH GALVIS-ALONSO; JOÃO PEREIRA LEITE. Plasticidade neuronal associada à epilepsia do lobo temporal mesial: insights a partir de estudos em humanos e em modelos animais. Journal of Epilepsy and Clinical Neurophysiology, v. 12, n. 1, p. 10-17, Mar. 2006.

ARAUJO‚ D.; DE ARAUJO‚ D.B.; PONTES-NETO‚ O.M.; ESCORSI-ROSSET‚ S.; SIMAO‚ G.N.; WICHERT-ANA‚ L.; VELASCO‚ T.R.; SAKAMOTO‚ A.C.; LEITE‚ J.P.; SANTOS‚ A.C. Language and motor FMRI activation in polymicrogyric cortex. Epilepsia, v. 47, n. 3, p. 589-592, 2006.

LUDMYLA KANDRATAVICIUS; JAIME EDUARDO CECÍLIO HALLAK; JOÃO PEREIRA LEITE. Expressão de proteínas de choque térmico na epilepsia do lobo temporal mesial. Journal of Epilepsy and Clinical Neurophysiology, v. 12, n. 3, p. 131-134, Set. 2006.

SALAMON‚ N.; ANDRES‚ M.; CHUTE‚ D.J.; NGUYEN‚ S.T.; CHANG‚ J.W.; HUYNH‚ M.N.; CHANDRA‚ P.S.; ANDRE‚ V.M.; CEPEDA‚ C.; LEVINE‚ M.S.; OTHERS. Contralateral hemimicrencephaly and clinical-pathological correlations in children with hemimegalencephaly. BRAIN, v. 129, n. 2, p. 352-365, 2006.