Development and application of microfluidic devices for electrophoresis with electrochemical detection

• Grant number: 06/03317-1
• Support Opportunities: Regular Research Grants
• Start date: February 01, 2007
• End date: March 31, 2009
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Analytical Chemistry
• Principal Investigator: Dosil Pereira de Jesus
• Grantee: Dosil Pereira de Jesus
• Host Institution: Instituto de Química (IQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil

Abstract

In this project microfluidic devices for electrophoresis will be manufactured on glass and/or polymeric substrates. A simple microfabrication technique, involving laser-printing toner (as structural material) depositition, and conventional ones, such as lithography will be used. Electrochemical detection (contactless conductometric and amperometric) will be implemented and evaluated in the microdevices. Electrokinetic and hydrodynamic sample injection systems will be developed in order to attain analysis with good precision and accuracy. Finally, methods for electrophoresis separation in the microdevices will be developed for determination of several compounds in samples of food, biological fluids, and others. (AU)