Evaluation of clinical risk factors for low bone mineral density and fractures in postmenopausal women

• Grant number: 08/10378-2
• Support Opportunities: Regular Research Grants
• Start date: February 01, 2009
• End date: July 31, 2011
• Field of knowledge: Health Sciences - Medicine - Maternal and Child Health
• Principal Investigator: Eliana Aguiar Petri Nahás
• Grantee: Eliana Aguiar Petri Nahás
• Host Institution: Faculdade de Medicina (FMB). Universidade Estadual Paulista (UNESP). Campus de Botucatu. Botucatu , SP, Brazil

Abstract

The evaluation of the factors associated with low bone mineral density (BMD) and fractures is of paramount importance in management postmenopausal women. The decline in bone mass and structural integrity results in increased risk for osteoporosis in women after the menopause. The major clinical consequence of osteoporosis is fracture. It is estimated that osteoporosis causes nine million fractures per year in women around the world. In the assessment of risk factors of morbidity, BMD is only one determinant. Other components should be considered as age, low weight, family history of fracture, prior fracture, smoking and risk of falling. The identification of risk for low bone mass and consequently of fracture is important in directing therapy in postmenopausal women. Thus, this study aims to evaluated the risk factors for low BMD and osteoporotic fracture and verify the conditions of equilibrium in women with and without osteoporosis, and between users and non-users of hormone therapy. It is hoped with this study to identify women at high risk for falls and osteoporotic fracture, thus introducing therapeutic measures that improvement of quality of life during menopause. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

CESAR RODRIGUES BARRAL, ANA BEATRIZ; PETRI NAHAS, ELIANA AGUIAR; NAHAS-NETO, JORGE; CANGUSSU, LUCIANA MENDES; BUTTROS, DAVI DE ARAUJO. Effect of hormone therapy on postural balance in postmenopausal women. MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY, v. 19, n. 7, p. 768-775, JUL 2012. (08/10378-2)

CANGUSSU, LUCIANA MENDES; NAHAS-NETO, JORGE; PETRI NAHAS, ELIANA AGUIAR; CESAR RODRIGUES BARRAL, ANA BEATRIZ; BUTTROS, DAVI DE ARAUJO; UEMURA, GILBERTO. Evaluation of postural balance in postmenopausal women and its relationship with bone mineral density- a cross sectional study. BMC MUSCULOSKELETAL DISORDERS, v. 13, JAN 16 2012. (08/10378-2)