Using systems biology approach to develop a model for whole plant functioning

• Grant number: 11/52065-3
• Support type: Research Grants - Research Partnership for Technological Innovation - PITE
• Duration: October 01, 2012 - March 31, 2017
• Field of knowledge: Biological Sciences - Botany - Pant Physiology
• Cooperation agreement: Microsoft Research
• Principal Investigator: Marcos Silveira Buckeridge
• Grantee: Marcos Silveira Buckeridge
• Home Institution: Instituto de Biociências (IB). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Company: Microsoft
• City: São Paulo
• Partner institutions: Microsoft
• Associated grant(s): 13/50316-4 - Impact of elevated CO2 and drought on metabolism of Sorghum, AP.R
• Associated scholarship(s): 15/13479-8 - Using systems biology approach to develop a model for whole plant functioning, BP.PD; 13/24205-0 - Development of a bioinformatic tool for integration of transcriptomics, proteomics and physiology using sorghum and sugarcane as model systems, BP.DR

Abstract

The advance of the sciences of the global climate changes and bioenergy require deep understanding of how plants work in a changing environment. Although model and native plants have been studied from the viewpoint of their ecophysiology, biochemistry and molecular biology, these levels of organization have not been approached in an integrated way. The limitation is the enormous amounts of data produced. This proposal aims at understanding the interaction among the different organizational levels through analysis of a data set from a C4 model plant (sorghum) cultivated at elevated CO2 combined with water deficit. We intend to obtain data on the physiology, metabolism and gene expression of sorghum grown in four different conditions: 1) ambient [CO2] well watered; 2) elevated [CO2] well watered; 3) ambient [CO2] with water deficit and 4) elevated [CO2] with water deficit. Two groups of plant sciences, will interact with one group of mathematics and computing sciences to reach the following goals: 1) test and refine tools for network analysis in biology; 2) develop tools for the integration of data from different experiments: 3) develop data visualization tools; 4) attempts to extrapolate to other species. (AU)

Scientific publications

(4)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

DE PINHO TAVARES, EVELINE QUEIROZ; MATTOS MARTINS, MARINA CAMARA; GRANDIS, ADRIANA; ROMIM, GRAYCE H.; PIOVEZANI, AMANDA RUSISKA; GAIARSA, JONAS WEISSMANN; BUCKERIDGE, MARCOS SILVEIRA. Newly identified miRNAs may contribute to aerenchyma formation in sugarcane roots. PLANT DIRECT, v. 4, n. 3 MAR 2020. Web of Science Citations: 0.

LOCOSSELLI, GIULIANO MASELLI; BUCKERIDGE, MARCOS SILVEIRA. Dendrobiochemistry, a missing link to further understand carbon allocation during growth and decline of trees. TREES-STRUCTURE AND FUNCTION, v. 31, n. 6, p. 1745-1758, DEC 2017. Web of Science Citations: 12.

TAVARES, EVELINE Q. P.; BUCKERIDGE, MARCOS S. Do plant cell walls have a code?. Plant Science, v. 241, p. 286-294, DEC 2015. Web of Science Citations: 9.

DE SOUZA, AMANDA P.; COCURON, JEAN-CHRISTOPHE; GARCIA, ANA CAROLINA; ALONSO, ANA PAULA; BUCKERIDGE, MARCOS S. Changes in Whole-Plant Metabolism during the Grain-Filling Stage in Sorghum Grown under Elevated CO2 and Drought. Plant Physiology, v. 169, n. 3, p. 1755-1765, NOV 2015. Web of Science Citations: 10.