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Effectiveness of mechanical brushing with different denture cleansing agents in reducing multi-species biofilm viability and their effects on the surface of acrylic resins

Grant number: 12/00608-6
Support Opportunities:Regular Research Grants
Duration: May 01, 2012 - April 30, 2014
Field of knowledge:Health Sciences - Dentistry - Dental Clinics
Principal Investigator:Eunice Teresinha Giampaolo
Grantee:Eunice Teresinha Giampaolo
Host Institution: Faculdade de Odontologia (FOAr). Universidade Estadual Paulista (UNESP). Campus de Araraquara. Araraquara , SP, Brazil


The aim of the current study is to investigate the effectiveness of combining toothbrushing with different cleansing agents (water/dentifrice, 1% chlorhexidine gluconate, 1% sodium hypochlorite, perborate- (CoregaTabs); and 0.2% peracetic acid) in inactivating multi-species biofilm (C. albicans, C. glabrata e S. mutans) in two acrylic resins. Additionally, the effect of these agents on the resins will be evaluated in the surface hardness, roughness and color stability. Circular specimens (10X2 mm) will be fabricated with an acrylic resin denture base (Lucitone 550) and an autopolymerized reline material (Tokuyama Rebase Fast II). To evaluate the viability of reducing the biofilm, the specimens will be subjected to brushing and immersion in solutions for 10s. The viability of cells will be evaluated by XTT reduction and colonies count method. The effect of these agents on the materials will be evaluated by means of hardness surface, roughness and color stability. Data obtained will be subjected to statistical analysis most appropriate for each of the variables involved in the research. (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
DIAS PANARIELLO, BEATRIZ HELENA; IZUMIDA, FERNANDA EMIKO; MOFFA, EDUARDO BUOZI; PAVARINA, ANA CLAUDIA; JORGE, JANAINA HABIB; GIAMPAOLO, EUNICE TERESINHA. Effect of mechanical toothbrushing combined with different denture cleansers in reducing the viability of a multispecies biofilm on acrylic resins. AMERICAN JOURNAL OF DENTISTRY, v. 29, n. 3, p. 154-160, . (12/00608-6)

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