Development of optimized and economically viable process for the production of biosilicate for treatment of dentinary hypersensibility

• Grant number: 03/13389-1
• Support Opportunities: Research Grants - Innovative Research in Small Business - PIPE
• Start date: August 01, 2004
• End date: July 31, 2006
• Field of knowledge: Engineering - Materials and Metallurgical Engineering - Nonmetallic Materials
• Principal Investigator: Christian Ravagnani
• Grantee: Christian Ravagnani
• Company: Vitrovita Instituto de Inovação em Vitrocerâmicos Importação e Exportação Ltda. - EPP
• City: São Carlos

Abstract

The scientific and business communities have put a lot of effort into the search for more satisfactory products for the treatment of dentinary hypersensibility. Vitrovita’s researchers developed on a laboratory scale, an innovative bioactive crystalline material, called biosilicate, which demonstrated excellent preliminary results in research in vitro and in vivo in the treatment of this hypersensibility. The objective of this project is to develop and optimize, up to pilot scale, an economically viable process for the production of biosilicate. The level of bioactivity of the material should be maintained in this stage, along with the percentage of crystallinity and crystalline phase and the purity and granulometric distribution appropriate for its use in the treatment and elimination of dentinary hypersensibility. To achieve these objectives, the company will develop research on the fusion of biosilicate, using different crucibles in the thermic treatments for the crystallization of the material and in its grinding so as to obtain the desired granulometric distribution. It is hoped, at the end of the project, to introduce on the market the first national product for the treatment of dentinary hypersensibility based on the concept of bioactive materials, offering greater practicality of the application, greater comfort for the patients and the lasting elimination of the problem. (AU)