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Investigation of treatment with 24-epibrassinolide in plant development, profile of volatile constituents and biological activities of essential oils from Cymbopogon citratus, Cymbopogon flexuosus and Mentha pulegium

Grant number: 12/09101-1
Support Opportunities:Regular Research Grants
Duration: October 01, 2012 - September 30, 2014
Field of knowledge:Health Sciences - Pharmacy - Pharmacognosy
Principal Investigator:Marcos José Salvador
Grantee:Marcos José Salvador
Host Institution: Instituto de Biologia (IB). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil

Abstract

Some essential oils have antibacterial and antifungal activities and antiproliferative effect against human cancer cell lines. Antimicrobial agents, including essential oils, are used as drugs and as preservatives in pharmaceutical and food industry. Essential oils have important applications in agriculture and in clinical and preventive dentistry. Brassinosteroids increased the levels of carbohydrates and essential oils in some plant species. Cymbopogon citratus and Cymbopogon flexuosus, popularly known as lemon balm and Mentha pulegium, popularly known as pennyroyal are species widely used for medical purposes in Brazil. The objectives of this project are: 1 - to evaluate the relationship between the effects of hormone on growth parameters, levels of carbohydrates from leaves of three species and content of essential oils, 2- to evaluate the effect of 24-epibrassinolide on the constitution of essential oils of leaves of the three species, 2 - to determine the antimicrobial and antiproliferative activities of the essential oils obtained from plants with and without treatment with 24-epibrassinolide. (AU)

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Scientific publications (6)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
OLIVEIRA, CRISTHIAN SANTOS; ALVAREZ, CARLOS JOSE; PEREIRA CABRAL, MARCIA REGINA; SARRAGIOTTO, MARIA HELENA; SALVADOR, MARCOS JOSE; ALVES STEFANELLO, MARIA ELIDA. Three new diterpenoids from the leaves of Salvia lachnostachys. NATURAL PRODUCT RESEARCH, . (17/03598-5, 12/09101-1, 06/06079-4, 15/03726-8)
WINIEWSKI, VANESSA; VERDAN, MARIA HELENA; OLIVEIRA, CRISTHIAN SANTOS; BARRETO RODRIGUES, TAYNA ELOYANE; SALVADOR, MARCOS JOSE; ALVES STEFANELLO, MARIA ELIDA. Two new naphthoquinone derivatives from Sinningia conspicua (Gesneriaceae). NATURAL PRODUCT RESEARCH, v. N/A, p. 6-pg., . (12/09101-1, 06/06079-4, 21/09693-5, 15/03726-8)
TERCO LEITE, PATRICIA REGINA; LORENCONE, BETHANIA ROSA; TAFARELO MORENO, KARYNE GARCIA; LOPES, KATIANA SIMOES; MACEDO MARQUES, ALINE APARECIDA; FORTINI, CLARA SOLIGO; CALLOI PALOZI, RHANANY ALAN; DALMAGRO, MARIANA; LEITE KASSUYA, CANDIDA APARECIDA; DOS SANTOS, ARIANY CARVALHO; et al. The NO-cGMP-K (+) Channel Pathway Participates in Diuretic and Cardioprotective Effects of Blutaparon portulacoides in Spontaneously Hypertensive Rats. Planta Medica, v. 88, n. 13, p. 11-pg., . (06/06079-4, 15/03726-8, 12/09101-1, 17/03598-5)
VERDAN, MARIA HELENA; WINIEWSKI, VANESSA; SCHARF, DILAMARA R.; SALVADOR, MARCOS JOSE; DE SA, EDUARDO L.; STEFANELLO, MARIA ELIDA A.. imeric naphthochromenes and other constituents from Sinningia allagophylla (Gesneriaceae. PHYTOCHEMISTRY LETTERS, v. 42, p. 104-108, . (06/06079-4, 12/09101-1, 15/03726-8, 17/03598-5)
HERNANDEZ-TASCO, ALVARO JOSE; TRONCHINI, RAFAELA APARECIDA; APAZA-CASTILLO, GLADYS ANGELICA; HOSAKA, GUILHERME KENICHI; QUINONES, NATALY RUIZ; GOULART, MARCELA CRISTINA; FANTINATTI-GARBOGGINI, FABIANA; SALVADOR, MARCOS JOSE. Diversity of bacterial and fungal endophytic communities presents in the leaf blades of Sinningia magnifica, Sinningia schiffneri and Sinningia speciosa from different cladus of Gesneriaceae family: A comparative analysis in three consecutive years. MICROBIOLOGICAL RESEARCH, v. 271, p. 10-pg., . (21/09693-5, 15/03726-8, 17/03598-5, 06/06079-4, 12/09101-1)

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