| Grant number: | 13/05485-2 |
| Support Opportunities: | Regular Research Grants |
| Start date: | June 01, 2013 |
| End date: | August 31, 2015 |
| Field of knowledge: | Agronomical Sciences - Veterinary Medicine - Preventive Veterinary Medicine |
| Principal Investigator: | Luciano Matsumiya Thomazelli |
| Grantee: | Luciano Matsumiya Thomazelli |
| Host Institution: | Instituto de Ciências Biomédicas (ICB). Universidade de São Paulo (USP). São Paulo , SP, Brazil |
| City of the host institution: | São Paulo |
| Associated researchers: | Edison Luiz Durigon ; Jansen de Araujo ; Marina Maria Moraes de Seixas ; Tatiana Ometto de Araujo |
Abstract
The Newcastle disease is an acute viral illness, mandatory notification, highly contagious affecting wild and commercial birds. Knowing that the Brazilian poultry farming is an activity of great success in Brazil, an outbreak of disease would represent a risk to the economy and consumption levels of quality protein and affordable to the population.Wild birds, especially migratory, may carry the Newcastle disease virus (NDV) to regions considered free of the disease, acting as agents transmitters in their long routes between wintering and nesting areas.With increasing human activity and consequent risk of introducing diseases into wildlife, in places as inhospitable as Antarctica, it is of great importance to study the epidemiology of NDV in migratory and seabirds also in these environments. Therefore, the objectives of this work is to analyze the presence of NDV in samples from wild birds, migratory and resident, in different regions of Brazil crossed by major South American migratory routes, and seabirds around the Brazilian Antarctic base, aimed an active epidemiological monitoring.About 1200 samples will be analyzed from the Bank's Sample Lab Clinical and Molecular Virology, Institute of Biomedical Sciences, University of São Paulo, with 400 samples collected from seabirds in the Antarctic region and over 800 samples collected from wild birds in different regions of Brazil. Also will be studied samples that still in the collection phase of other projects related to the laboratory.The samples will be tested for the detection of genetic material of NDV using the technique of Real Time Polymerase Chain Reaction (RT-PCR) with primers described in the literature. The detected virus will be genetically characterized and their hosts analyzed according to their ecologies and migration routes, to identify potential risks to public and animal health, contributing to a better understanding of the etiology and epidemiology of NDV in Brazil and Antarctica. (AU)
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