Multigenic analysis of avian group a rotavirus from Brazilian poultry farms

• Grant number: 14/13531-7
• Support Opportunities: Regular Research Grants
• Start date: October 01, 2014
• End date: September 30, 2016
• Field of knowledge: Agronomical Sciences - Veterinary Medicine - Preventive Veterinary Medicine
• Principal Investigator: Fábio Gregori
• Grantee: Fábio Gregori
• Host Institution: Faculdade de Medicina Veterinária e Zootecnia (FMVZ). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

Rotaviruses are major viral agents related to enterophaties both in mammals and avian species. To date, research regarding the rotavirus role on the avian diarrhea are scarce, affecting the productivity of this sector in agribusiness. The objective of this project is to characterize the Group A rotavirus non-structural protein coding genes (NSP1, NSP2, NSP3, NSP4 and NSP5/6) and the structural (VP1, VP2, VP3 and VP6) from fecal samples from birds raised in many Brazilian commercial avian farms, by RT-PCR, followed by nucleotide sequencing and phylogenetic inferences. In doing so, it will provide a better understanding of rotavirus epidemiology, by the definition of genetic variability of circulating strains, a necessary step for effective prophylactic measures of the disease. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

BESERRA, LAILA A. R.; BARBOSA, CARLA M.; BERG, MIKAEL; BRANDAO, PAULO E.; SOARES, RODRIGO M.; GREGORI, FABIO. Genome constellations of rotavirus a isolated from avian species in Brazil, 2008-2015. Brazilian Journal of Microbiology, v. 51, n. 3, MAY 2020. (14/13531-7)