Use of drugs containing nanocarriers with photosensitizers and/or other active compounds applied to cell therapy and treatment of central nervous system disorders

• Grant number: 13/50181-1
• Support Opportunities: Research Projects - Thematic Grants
• Start date: June 01, 2015
• End date: March 31, 2021
• Field of knowledge: Health Sciences - Pharmacy - Pharmaceutical Technology
• Principal Investigator: Antonio Claudio Tedesco
• Grantee: Antonio Claudio Tedesco
• Host Institution: Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto (FFCLRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
• Pesquisadores principais: Sergio Cavalheiro
• Associated research grant(s): 18/01608-6 - 19th European Symposium on Radiopharmacy and Radiopharmaceuticals, AR.EXT; 17/01273-1 - Multi-user equipament approved in grants 13/50181-1:spectrofluorometer model RF-6000 Shmadzu and accessories, AP.EMU; 17/04915-4 - Multi-user equipament approved in grants 13/50181-1: Bio-Scaffold printer 3D 3axis com precisão nos eixos XYZ- 3D, AP.EMU
• Associated scholarship(s): 20/06523-9 - Use of nanocarriers containing photosensitizing drugs and other actives applied to cell therapy of central nervous system pathologies treatment, BP.PD; 19/04801-4 - Use of nanocarriers containing photosensitizing drugs and other actives applied to cell therapy and treatment of pathologies of the central nervous system, BP.TT; 18/24004-9 - Nanocarriers loaded with photosensitizers and others drugs derived of growth factors applied to Photodynamic Processes in treatment of central nervous system diseases, BP.PD; 15/18684-9 - Use of drugs containing nanocarriers with photosensitizers and/or other active compounds applied to cell therapy and treatment of central nervous system disorders, BP.PD; 14/11870-9 - Sensitizing cancer cell lines to photodynamic therapy through inhibition of protein APE1, BP.PD

Abstract

The central nervous system (CNS) is composed of astrocytes (50%), oligodendrocytes (40%), microglia (5%) and ependymal cells (5%) which provide structural and functional support to neurons. In particular glial tumors (glioma or, glioblastoma) are among ... (AU)

Scientific publications

(62)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

PADILHA-NAKAGHI, LUCIANA C.; USCATEGUI, RICARDO A. R.; OLIVEIRA, MARIA EMILIA F.; NOCITI, RICARDO P.; MACENTE, I, BEATRICE; COUTINHO, LEANDRO N.; NAKAGHI, EDUARDO YO; MOTTA, GUILHERME A.; SANTOS, VICTOR J. C.; MACIEL, GIOVANNA S.; et al. Local alpha 1-adrenergic blockers: An alternative for sheep cervix dilation?. Animal Reproduction Science, v. 222, NOV 2020. (13/50181-1)

JAYME, CRISTIANO CERON; CALORI, ITALO RODRIGO; TEDESCO, ANTONIO CLAUDIO. Spectroscopic analysis of aluminum chloride phthalocyanine in binary water/ethanol systems for the design of a new drug delivery system for photodynamic therapy cancer treatment. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, v. 153, p. 178-183, JAN 15 2016. (13/50181-1)

DAVANZO, NATHALIA NOSSI; PELLOSI, DIOGO SILVA; FRANCHI, LEONARDO PEREIRA; TEDESCO, ANTONIO CLAUDIO. Light source is critical to induce glioblastoma cell death by photodynamic therapy using chloro-aluminiumphtalocyanine albumin-based nanoparticles. Photodiagnosis and Photodynamic Therapy, v. 19, p. 181-183, SEP 2017. (16/00389-3, 13/50181-1, 14/11870-9)

PELLOSI, DIOGO SILVA; CALORI, ITALO RODRIGO; DE PAULA, LEONARDO BARCELOS; HIOKA, NOBORU; QUAGLIA, FABIANA; TEDESCO, ANTONIO CLAUDIO. Multifunctional theranostic Pluronic mixed micelles improve targeted photoactivity of Verteporfin in cancer cells. Materials Science & Engineering C-Materials for Biological Applications, v. 71, p. 1-9, FEB 1 2017. (13/50181-1, 16/00389-3, 15/18684-9)

GOTO, PATRICIA L.; SIQUEIRA-MOURA, MARIGILSON P.; TEDESCO, ANTONIO C.. Application of aluminum chloride phthalocyanine-loaded solid lipid nanoparticles for photodynamic inactivation of melanoma cells. International Journal of Pharmaceutics, v. 518, n. 1-2, p. 228-241, FEB 25 2017. (13/50181-1)

SIMIONI, ANDREZA RIBEIRO; CARVALHO DE JESUS, PRISCILA COSTA; TEDESCO, ANTONIO CLAUDIO. Layer-by-layer hollow photosensitizer microcapsule design via a manganese carbonate hard template for photodynamic therapy in cells. Photodiagnosis and Photodynamic Therapy, v. 22, p. 169-177, JUN 2018. (13/50181-1)

MONGE-FUENTES, VICTORIA; MAYER, ANDREIA BIOLCHI; LIMA, MARCOS ROBALINHO; GERALDES, LUIZA RIBEIRO; ZANOTTO, LARISSA NEPOMUCENO; MOREIRA, KARLA GRAZIELLA; MARTINS, OLIMPIA PASCHOAL; PIVA, HENRIQUE LUIS; SOARES FELIPE, MARIA SUELI; AMARAL, ANDRE CORREA; et al. Dopamine-loaded nanoparticle systems circumvent the blood-brain barrier restoring motor function in mouse model for Parkinson's Disease. SCIENTIFIC REPORTS, v. 11, n. 1, JUL 26 2021. (13/50181-1)

SOBRAL, V, DANIELLE; FUSCALDI, LEONARDO L.; DURANTE, ANA CLAUDIA R.; RANGEL, MAYARA G.; OLIVEIRA, LARISSA R.; MENDONCA, FERNANDA F.; MIRANDA, ANA CLAUDIA C.; CABEZA, JORGE M.; MONTOR, WAGNER R.; CABRAL, FRANCISCO R.; et al. Radiochemical and biological properties of peptides designed to interact with EGF receptor: Relevance for glioblastoma. NUCLEAR MEDICINE AND BIOLOGY, v. 88-89, p. 14-23, SEP-OCT 2020. (13/50181-1)

CALORI, ITALO RODRIGO; JAYME, CRISTIANO CERON; UENO, LEONARDO TSUYOSHI; CORRETO MACHADO, FRANCISCO BOLIVAR; TEDESCO, ANTONIO CLAUDIO. Theoretical and experimental studies concerning monomer/aggregates equilibrium of zinc phthalocyanine for future photodynamic action. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, v. 214, p. 513-521, MAY 5 2019. (18/10237-1, 13/50181-1)

REZENDE, NAYARA; JAYME, CRISTIANO CERON; BRASSESCO, MARIA SOL; TEDESCO, ANTONIO CLAUDIO; DE OLIVEIRA, HARLEY FRANCISCO. Standardization of a resazurin-based assay for the evaluation of metabolic activity in oral squamous carcinoma and glioblastoma cells. Photodiagnosis and Photodynamic Therapy, v. 26, p. 371-374, JUN 2019. (18/10237-1, 13/50181-1, 14/09421-1)

CALORI, ITALO RODRIGO; TEDESCO, ANTONIO CLAUDIO. Aluminum chloride phthalocyanine in MCF-7: Rationally accounting for state of aggregation of photosensitizers inside cells. DYES AND PIGMENTS, v. 173, FEB 2020. (13/50181-1)

SOUZA, CARLA; JAYME, CRISTIANO CERON; REZENDE, NAYARA; TEDESCO, ANTONIO CLAUDIO. Synergistic effect of photobiomodulation and phthalocyanine photosensitizer on fibroblast signaling responses in an in vitro three-dimensional microenvironment. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, v. 222, SEP 2021. (13/50181-1, 18/10237-1, 17/01272-5)

CURYLOFO-ZOTTI, FABIANA ALMEIDA; OLIVEIRA, VIVIANE DE CASSIA; MARCHESIN, ANALU RODRIGUEZ; BORGES, HIAGO SALGE; TEDESCO, ANTONIO CLAUDIO; CORONA, SILMARA APARECIDA MILORI. In vitro antibacterial activity of green tea-loaded chitosan nanoparticles on caries-related microorganisms and dentin after Er:YAG laser caries removal. Lasers in Medical Science, v. 38, n. 1, p. 8-pg., 2023-01-23. (13/50181-1, 18/23862-1, 17/11582-1, 17/00720-4, 19/04807-2)

JAYME, CRISTIANO CERON; PIRES, ANANDA FERREIRA; FERNANDES, DANIELA SILVESTRINI; BI, HONG; TEDESCO, ANTONIO CLAUDIO. DNA polymer films used as drug delivery systems to early-stage diagnose and treatment of breast cancer using 3D tumor spheroids as a model. Photodiagnosis and Photodynamic Therapy, v. 37, p. 12-pg., 2022-03-01. (18/10237-1, 13/50181-1)

CALORI, ITALO RODRIGO; BRAGA, GUSTAVO; CARVALHO DE JESUS, PRISCILA DA COSTA; BI, HONG; TEDESCO, ANTONIO CLAUDIO. Polymer scaffolds as drug delivery systems. EUROPEAN POLYMER JOURNAL, v. 129, APR 15 2020. (13/50181-1)

DE MELO, MARYANNE TRAFANI; PIVA, HENRIQUE LUIS; TEDESCO, ANTONIO CLAUDIO. Design of new protein drug delivery system (PDDS) with photoactive compounds as a potential application in the treatment of glioblastoma brain cancer. Materials Science & Engineering C-Materials for Biological Applications, v. 110, MAY 2020. (13/50181-1)

JAYME, CRISTIANO CERON; CALORI, ITALO RODRIGO; FREIRE CUNHA, ELISE MARQUES; TEDESCO, ANTONIO CLAUDIO. Evaluation of aluminum phthalocyanine chloride and DNA interactions for the design of an advanced drug delivery system in photodynamic therapy. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, v. 201, p. 242-248, AUG 5 2018. (13/50181-1)

PELLOSI, DIOGO SILVA; CARVALHO DE JESUS, PRISCILA DA COSTA; TEDESCO, ANTONIO CLAUDIO. Spotlight on the delivery of photosensitizers: different approaches for photodynamic-based therapies. Expert Opinion on Drug Delivery, v. 14, n. 12, p. 1395-1406, 2017. (13/50181-1)

TEDESCO, ANTONIO CLAUDIO; SILVA, EMANOEL P. O.; JAYME, CRISTIANO C.; PIVA, HENRIQUE L.; FRANCHI, LEONARDO P.. Cholesterol-rich nanoemulsion (LDE) as a novel drug delivery system to diagnose, delineate, and treat human glioblastoma. Materials Science & Engineering C-Materials for Biological Applications, v. 123, APR 2021. (12/25216-3, 18/10237-1, 13/50181-1, 14/11870-9)

VENDETTE, ANTONIO CARLOS FIGUEIREDO; PIVA, HENRIQUE LUIS; MUEHLMANN, LUIS ALEXANDRE; DE SOUZA, DELFRANK ANANIAS; TEDESCO, ANTONIO CLAUDIO; AZEVEDO, RICARDO BENTES. Clinical treatment of intra-epithelia cervical neoplasia with photodynamic therapy. INTERNATIONAL JOURNAL OF HYPERTHERMIA, v. 37, n. 3, p. 9-pg., 2020-12-15. (13/50181-1)

CALORI, ITALO RODRIGO; PIVA, HENRIQUE LUIS; TEDESCO, ANTONIO CLAUDIO. Targeted cancer therapy using alpha-cyano-4-hydroxycinnamic acid as a novel vector molecule: A proof-of-concept study. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, v. 57, JUN 2020. (13/50181-1)

OLIVEIRA, P. M.; LOPES, T. Z.; TEDESCO, A. C.; RAHAL, P.; CALMON, M. F.. Effect of berberine associated with photodynamic therapy in cell lines. Photodiagnosis and Photodynamic Therapy, v. 32, DEC 2020. (13/50181-1, 15/16660-5)

CABRAL, AGATA SILVA; RIVAS LEONEL, ELLEN CRISTINA; CANDIDO, NATALIA MARIA; PIVA, HENRIQUE LUIS; DE MELO, MARYANNE TRAFANI; TABOGA, SEBASTIAO ROBERTO; RAHAL, PAULA; TEDESCO, ANTONIO CLAUDIO; CALMON, MARILIA FREITAS. Combined photodynamic therapy with chloroaluminum phthalocyanine and doxorubicin nanoemulsions in breast cancer model. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, v. 218, MAY 2021. (20/04009-6, 13/50181-1)

GUSMAO, LUIZA ARAUJO; MATSUO, FLAVIA SAYURI; BARBOSA, HELLEN FRANCIANE GONCALVES; TEDESCO, ANTONIO CLAUDIO. Advances in nano-based materials for glioblastoma multiforme diagnosis: A mini-review. FRONTIERS IN NANOTECHNOLOGY, v. 4, p. 14-pg., 2022-08-31. (13/50181-1, 18/17911-0)

FRANCHI, LEONARDO PEREIRA; BARBOSA DE FREITAS LIMA, JESSICA ELLEN; PIVA, HENRIQUE LUIS; TEDESCO, ANTONIO CLAUDIO. The redox function of apurinic/apyrimidinic endonuclease 1 as key modulator in photodynamic therapy. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, v. 211, p. 13-pg., 2020-10-01. (17/14630-7, 13/50181-1, 14/11870-9)

MONICO, DANIELLI AZEVEDO; CALORI, ITALO RODRIGO; SOUZA, CARLA; ESPREAFICO, ENILZA MARIA; BI, HONG; TEDESCO, ANTONIO CLAUDIO. Melanoma spheroid-containing artificial dermis as an alternative approach to in vivo models. Experimental Cell Research, v. 417, n. 1, p. 11-pg., 2022-05-20. (20/04507-6, 13/50181-1, 17/01272-5)

BARBOSA, HELLEN FRANCIANE GONCALVES; PIVA, HENRIQUE LUIS; MATSUO, FLAVIA SAYURI; DE LIMA, SARAH CAROLINE GOMES; DE SOUZA, LUCAS EDUARDO BOTELHO; OSAKO, MARIANA KIOMY; TEDESCO, ANTONIO CLAUDIO. Hybrid lipid-biopolymer nanocarrier as a strategy for GBM photodynamic therapy (PDT). International Journal of Biological Macromolecules, v. 242, p. 14-pg., 2023-05-08. (18/17911-0, 13/50181-1, 20/04009-6)

BORGES, HIAGO SALGE; GUSMAO, LUIZA ARAUJO; TEDESCO, ANTONIO CLAUDIO. Multi-charged nanoemulsion for photodynamic treatment of glioblastoma cell line in 2D and 3D in vitro models. Photodiagnosis and Photodynamic Therapy, v. 43, p. 12-pg., 2023-09-01. (13/50181-1)

FERREIRA-SILVA, VALERIA; PRIMO, FERNANDO L.; BAQUI, MUNIRA M. A.; MAGALHAES, DANIELLE A. R.; ORELLANA, MARISTELA D.; CASTILHO-FERNANDES, ANDRIELLE; CRUZ, MARIO C.; CAMARA, NIEHLS O. S.; COVAS, DIMAS T.; TEDESCO, ANTONIO C.. Beneficial Role of Low-Intensity Laser Irradiation on Neural beta-tubulin III Protein Expression in Human Bone Marrow Multipotent Mesenchymal Stromal Cells. STEM CELL REVIEWS AND REPORTS, v. 14, n. 4, p. 585-598, AUG 2018. (13/50181-1)

VENDETTE, ANTONIO CARLOS FIGUEIREDO; PIVA, HENRIQUE LUIS; MUEHLMANN, LUIS ALEXANDRE; DE SOUZA, DELFRANK ANANIAS; TEDESCO, ANTONIO CLAUDIO; AZEVEDO, RICARDO BENTES. Clinical treatment of intra-epithelia cervical neoplasia with photodynamic therapy. INTERNATIONAL JOURNAL OF HYPERTHERMIA, v. 37, n. 3, SI, p. 50-58, DEC 15 2020. (13/50181-1)

FERREIRA PIRES, ANANDA. Development of DNA polymer films as a drug delivery system for the treatment of oral cancer. DRUG DELIVERY AND TRANSLATIONAL RESEARCH, v. 10, n. 6, SI, JUN 2020. (13/50181-1, 18/10237-1)

LEANDRO, FERNANDA Z.; MARTINS, JULIA; FONTES, APARECIDA M.; TEDESCO, ANTONIO C.. Evaluation of theranostic nanocarriers for near-infrared imaging and photodynamic therapy on human prostate cancer cells. COLLOIDS AND SURFACES B-BIOINTERFACES, v. 154, p. 341-349, JUN 1 2017. (13/50181-1, 08/53719-4)

SILVA, E. P. O.; FRANCHI, L. P.; TEDESCO, A. C.. Chloro-aluminium phthalocyanine loaded in ultradeformable liposomes for photobiology studies on human glioblastoma. RSC ADVANCES, v. 6, n. 83, p. 79631-79640, 2016. (12/25216-3, 13/50181-1, 14/11870-9)

CALORI, ITALO RODRIGO; TEDESCO, ANTONIO CLAUDIO. Lipid vesicles loading aluminum phthalocyanine chloride: Formulation properties and disaggregation upon intracellular delivery. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, v. 160, p. 240-247, JUL 2016. (13/50181-1)

DE PAULA, L. B.; PRIMO, F. L.; PINTO, M. R.; MORAIS, P. C.; TEDESCO, A. C.. Evaluation of a chloroaluminium phthalocyanine-loaded magnetic nanoemulsion as a drug delivery device to treat glioblastoma using hyperthermia and photodynamic therapy. RSC ADVANCES, v. 7, n. 15, p. 9115-9122, 2017. (15/18684-9, 13/50181-1)

CALORI, ITALO RODRIGO; BI, HONG; TEDESCO, ANTONIO CLAUDIO. Expanding the Limits of Photodynamic Therapy: The Design of Organelles and Hypoxia-Targeting Nanomaterials for Enhanced Photokilling of Cancer. ACS APPLIED BIO MATERIALS, v. 4, n. 1, p. 195-228, JAN 18 2021. (20/06523-9, 13/50181-1)

PELLOSI, DIOGO SILVA; MACAROFF, PATRICIA PEREIRA; MORAIS, PAULO CESAR; TEDESCO, ANTONIO CLAUDIO. Magneto low-density nanoemulsion (MLDE): A potential vehicle for combined hyperthermia and photodynamic therapy to treat cancer selectively. Materials Science & Engineering C-Materials for Biological Applications, v. 92, p. 103-111, NOV 1 2018. (15/18684-9, 16/00389-3, 13/50181-1)

SALLES DE OLIVEIRA, DAPHNE CHRISTINE; DE FREITAS, CAMILA FABIANO; CALORI, ITALO RODRIGO; GONCALVES, RENATO SONCHINI; ERRERIAS FERNANDES CARDINALI, CAMILA APARECIDA; MALACARNE, LUIS CARLOS; RAVANELLI, MARIA IDA; DE OLIVEIRA, HUEDER PAULO MOISES; TEDESCO, ANTONIO CLAUDIO; CAETANO, WILKER; et al. Theranostic verteporfin- loaded lipid-polymer liposome for photodynamic applications. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, v. 212, NOV 2020. (13/50181-1)

CASTILHO-FERNANDES, ANDRIELLE; LOPES, TACILA G.; PRIMO, FERNANDO L.; PINTO, MARCELO R.; TEDESCO, ANTONIO C.. Photodynamic process induced by chloro-aluminum phthalocyanine nanoemulsion in glioblastoma. Photodiagnosis and Photodynamic Therapy, v. 19, p. 221-228, SEP 2017. (13/50181-1, 16/21504-5)

FRANCHI, LEONARDO PEREIRA; AMANTINO, CAMILA F.; MELO, MARYANNE T.; DE LIMA MONTALDI, ANA PAULA; PRIMO, FERNANDO L.; TEDESCO, ANTONIO CLAUDIO. In vitro effects of photodynamic therapy induced by chloroaluminum phthalocyanine nanoemulsion. Photodiagnosis and Photodynamic Therapy, v. 16, p. 100-105, DEC 2016. (13/50181-1, 14/11870-9)

CALORI, ITALO RODRIGO; ALVES, SAMARA RODRIGUES; BI, HONG; TEDESCO, ANTONIO CLAUDIO. Type-I Collagen/Collagenase Modulates the 3D Structure and Behavior of Glioblastoma Spheroid Models. ACS APPLIED BIO MATERIALS, v. 5, n. 2, p. 11-pg., 2022-02-21. (20/04507-6, 13/50181-1)

UNTEN TAKAHASHI, LUANDRA APARECIDA; MILORI CORONA, SILMARA APARECIDA. Conjugate of chitosan nanoparticles with chloroaluminium phthalocyanine: Synthesis, characterization and photoinactivation of Streptococcus mutans biofilm. Photodiagnosis and Photodynamic Therapy, v. 30, JUN 2020. (13/50181-1, 19/05965-0)

DE ANDRADE, LAISE R.; TEDESCO, ANTONIO C.; PRIMO, FERNANDO L.; FARIAS, GABRIEL R.; DA SILVA, JAQUELINE R.; LONGO, JOAO P. F.; DE ALMEIDA, MARCOS C.; DE SOUZA, PAULO E. N.; DE AZEVEDO, RICARDO B.; PINHEIRO, WILLIE O.; et al. Tumor cell death in orthotopic breast cancer model by NanoALA: a novel perspective on photodynamic therapy in oncology. Nanomedicine, v. 15, n. 10, p. 1019-1036, APR 2020. (13/50181-1)

FERREIRA-SILVA, VALERIA; PRIMO, FERNANDO L.; BAQUI, MUNIRA M. A.; MAGALHAES, DANIELLE A. R.; ORELLANA, MARISTELA D.; CASTILHO-FERNANDES, ANDRIELLE; CRUZ, MARIO C.; CAMARA, NIEHLS O. S.; COVAS, DIMAS T.; TEDESCO, ANTONIO C.. Beneficial Role of Low-Intensity Laser Irradiation on Neural beta-tubulin III Protein Expression in Human Bone Marrow Multipotent Mesenchymal Stromal Cells. STEM CELL REVIEWS AND REPORTS, v. 14, n. 4, p. 14-pg., 2018-08-01. (13/50181-1)

CURYLOFO-ZOTTI, FABIANA ALMEIDA; TEDESCO, ANTONIO CLAUDIO; LIZARELLI, GUSTAVO TEODORO COSTA; TAKAHASHI, LUANDRA APARECIDA UNTEN; CORONA, SILMARA APARECIDA MILORI. Effect of green tea-loaded chitosan nanoparticles on leathery dentin microhardness. ODONTOLOGY, v. 109, n. 4, p. 8-pg., 2021-05-08. (17/11582-1, 13/50181-1, 19/04807-2)

CERON JAYME, CRISTIANO; FERREIRA PIRES, ANANDA; TEDESCO, ANTONIO CLAUDIO. Development of DNA polymer films as a drug delivery system for the treatment of oral cancer. DRUG DELIVERY AND TRANSLATIONAL RESEARCH, v. 10, n. 6, p. 14-pg., 2020-06-22. (18/10237-1, 13/50181-1)

CALORI, ITALO RODRIGO; PINHEIRO, LUKAS; BRAGA, GUSTAVO; PEDROSO DE MORAIS, FLAVIA AMANDA; CAETANO, WILKER; TEDESCO, ANTONIO CLAUDIO; HIOKA, NOBORU. Interaction of triblock copolymers (Pluronic (R)) with DMPC vesicles: a photophysical and computational study. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, v. 275, p. 10-pg., 2022-07-05. (20/04507-6, 13/50181-1)

CALORI, ITALO RODRIGO; BRAGA, GUSTAVO; TESSARO, ANDRE LUIZ; CAETANO, WILKER; TEDESCO, ANTONIO CLAUDIO; HIOKA, NOBORU. Self-aggregation of the proteolytic forms of Verteporfin: An in silico and in vitro study. JOURNAL OF MOLECULAR LIQUIDS, v. 352, p. 9-pg., 2022-02-14. (20/04507-6, 13/50181-1)

GOBO, GRACIELY GOMIDES; PIVA, HENRIQUE LUIS; TEDESCO, ANTONIO CLAUDIO; PRIMO, FERNANDO LUCAS. Novel quinizarin spray-dried nanoparticles for treating melanoma with photodynamic therapy. MATERIALS TODAY COMMUNICATIONS, v. 33, p. 9-pg., 2022-11-11. (13/50181-1, 20/04009-6)

JAYME, CRISTIANO CERON; REZENDE, NAYARA; FERNANDES, DANIELA S. .; PAULA, LEONARDO B. DE; DE CASTRO, BARBARA GIMENES; TAKAHASHI, LUANDRA APARECIDA U. .; TEDESCO, ANTONIO CLAUDIO. Target selectivity of cholesterol-phosphatidylcholine liposome loaded with phthalocyanine for breast cancer diagnosis and treatment by photodynamic therapy. Photodiagnosis and Photodynamic Therapy, v. 39, p. 6-pg., 2022-07-25. (18/24004-9, 21/02207-8, 18/10237-1, 15/18684-9, 13/50181-1)

JAYME, CRISTIANO CERON; SOUZA, CARLA; FERNANDES, DANIELA SILVESTRINI; TEDESCO, ANTONIO CLAUDIO. Tailoring the growth and proliferation of human dermal fibroblasts by DNA-based polymer films for skin regeneration. Journal of Biomedical Materials Research Part A, v. 109, n. 11, p. 2381-2391, NOV 2021. (17/01272-5, 18/10237-1, 13/50181-1)

JAYME, CRISTIANO CERON; DE PAULA, LEONARDO BARCELOS; REZENDE, NAYARA; CALORI, ITALO RODRIGO; FRANCHI, LEONARDO PEREIRA; TEDESCO, ANTONIO CLAUDIO. DNA polymeric films as a support for cell growth as a new material for regenerative medicine: Compatibility and applicability. Experimental Cell Research, v. 360, n. 2, p. 404-412, NOV 15 2017. (15/18684-9, 13/50181-1, 14/11870-9)

SOUZA, CARLA; MONICO, DANIELLI AZEVEDO; TEDESCO, ANTONIO CLAUDIO. Implications of dichlorofluorescein photoinstability for detection of UVA-induced oxidative stress in fibroblasts and keratinocyte cells. PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES, v. 19, n. 1, p. 40-48, JAN 1 2020. (13/50181-1, 17/01272-5)

SOUZA, CARLA; PELLOSI, DIOGO SILVA; TEDESCO, ANTONIO CLAUDIO. Prodrugs for targeted cancer therapy. EXPERT REVIEW OF ANTICANCER THERAPY, v. 19, n. 6, p. 483-502, JUN 3 2019. (16/00389-3, 13/50181-1, 17/01272-5)

PELLOSI, DIOGO S.; PAULA, LEONARDO B.; DE MELO, MARYANNE T.; TEDESCO, ANTONIO C.. Targeted and Synergic Glioblastoma Treatment: Multifunctional Nanoparticles Delivering Verteporfin as Adjuvant Therapy for Temozolomide Chemotherapy. MOLECULAR PHARMACEUTICS, v. 16, n. 3, p. 1009-1024, MAR 2019. (13/50181-1, 16/00389-3, 18/24004-9, 15/18684-9)

CASTILHO-FERNANDES, ANDRIELLE; LOPES, TADLA G.; FERREIRA, FERNANDO U.; REZENDE, NAYARA; SILVA, VALERIA F.; PRIMO, FERNANDO L.; FONTES, APARECIDA MARIA; RIBEIRO-SILVA, ALFREDO; TEDESCO, ANTONIO CLAUDIO. Adipogenic differentiation of murine bone marrow mesenchymal stem cells induced by visible light via photo- induced biomodulation. Photodiagnosis and Photodynamic Therapy, v. 25, p. 119-127, MAR 2019. (13/50181-1)

ALVES, SAMARA RODRIGUES; CALORI, ITALO RODRIGO; TEDESCO, ANTONIO CLAUDIO. Photosensitizer-based metal-organic frameworks for highly effective photodynamic therapy. Materials Science & Engineering C-Materials for Biological Applications, v. 131, DEC 2021. (20/04507-6, 13/50181-1)

RIBEIRO CAVALCANTE, LEONARDO LOBO; TEDESCO, ANTONIO CLAUDIO; SOUZA-GABRIEL, ALINE EVANGELISTA; BORGES, HIAGO SALGE; CURYLOFO-ZOTTI, FABIANA ALMEIDA; MILORI CORONA, SILMARA APARECIDA. Photoinactivation of multispecies cariogenic biofilm mediated by aluminum phthalocyanine chloride encapsulated in chitosan nanoparticles. Lasers in Medical Science, NOV 2021. (13/50181-1, 19/05965-0)

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