Research Grants 13/50181-1 - Fármacos fotossensibilizantes, Sistema nervoso central - BV FAPESP
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Use of drugs containing nanocarriers with photosensitizers and/or other active compounds applied to cell therapy and treatment of central nervous system disorders

Grant number: 13/50181-1
Support Opportunities:Research Projects - Thematic Grants
Start date: June 01, 2015
End date: March 31, 2021
Field of knowledge:Health Sciences - Pharmacy - Pharmaceutical Technology
Principal Investigator:Antonio Claudio Tedesco
Grantee:Antonio Claudio Tedesco
Host Institution: Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto (FFCLRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
Pesquisadores principais:
Sergio Cavalheiro
Associated research grant(s):18/01608-6 - 19th European Symposium on Radiopharmacy and Radiopharmaceuticals, AR.EXT
17/01273-1 - Multi-user equipament approved in grants 13/50181-1:spectrofluorometer model RF-6000 Shmadzu and accessories, AP.EMU
17/04915-4 - Multi-user equipament approved in grants 13/50181-1: Bio-Scaffold printer 3D 3axis com precisão nos eixos XYZ- 3D, AP.EMU
Associated scholarship(s):20/06523-9 - Use of nanocarriers containing photosensitizing drugs and other actives applied to cell therapy of central nervous system pathologies treatment, BP.PD
19/04801-4 - Use of nanocarriers containing photosensitizing drugs and other actives applied to cell therapy and treatment of pathologies of the central nervous system, BP.TT
18/24004-9 - Nanocarriers loaded with photosensitizers and others drugs derived of growth factors applied to Photodynamic Processes in treatment of central nervous system diseases, BP.PD
15/18684-9 - Use of drugs containing nanocarriers with photosensitizers and/or other active compounds applied to cell therapy and treatment of central nervous system disorders, BP.PD
14/11870-9 - Sensitizing cancer cell lines to photodynamic therapy through inhibition of protein APE1, BP.PD

Abstract

The central nervous system (CNS) is composed of astrocytes (50%), oligodendrocytes (40%), microglia (5%) and ependymal cells (5%) which provide structural and functional support to neurons. In particular glial tumors (glioma or, glioblastoma) are among ... (AU)

Articles published in Agência FAPESP Newsletter about the research grant:
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Scientific publications (62)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
PADILHA-NAKAGHI, LUCIANA C.; USCATEGUI, RICARDO A. R.; OLIVEIRA, MARIA EMILIA F.; NOCITI, RICARDO P.; MACENTE, I, BEATRICE; COUTINHO, LEANDRO N.; NAKAGHI, EDUARDO YO; MOTTA, GUILHERME A.; SANTOS, VICTOR J. C.; MACIEL, GIOVANNA S.; et al. Local alpha 1-adrenergic blockers: An alternative for sheep cervix dilation?. Animal Reproduction Science, v. 222, . (13/50181-1)
JAYME, CRISTIANO CERON; CALORI, ITALO RODRIGO; TEDESCO, ANTONIO CLAUDIO. Spectroscopic analysis of aluminum chloride phthalocyanine in binary water/ethanol systems for the design of a new drug delivery system for photodynamic therapy cancer treatment. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, v. 153, p. 178-183, . (13/50181-1)
DAVANZO, NATHALIA NOSSI; PELLOSI, DIOGO SILVA; FRANCHI, LEONARDO PEREIRA; TEDESCO, ANTONIO CLAUDIO. Light source is critical to induce glioblastoma cell death by photodynamic therapy using chloro-aluminiumphtalocyanine albumin-based nanoparticles. Photodiagnosis and Photodynamic Therapy, v. 19, p. 181-183, . (16/00389-3, 13/50181-1, 14/11870-9)
PELLOSI, DIOGO SILVA; CALORI, ITALO RODRIGO; DE PAULA, LEONARDO BARCELOS; HIOKA, NOBORU; QUAGLIA, FABIANA; TEDESCO, ANTONIO CLAUDIO. Multifunctional theranostic Pluronic mixed micelles improve targeted photoactivity of Verteporfin in cancer cells. Materials Science & Engineering C-Materials for Biological Applications, v. 71, p. 1-9, . (13/50181-1, 16/00389-3, 15/18684-9)
GOTO, PATRICIA L.; SIQUEIRA-MOURA, MARIGILSON P.; TEDESCO, ANTONIO C.. Application of aluminum chloride phthalocyanine-loaded solid lipid nanoparticles for photodynamic inactivation of melanoma cells. International Journal of Pharmaceutics, v. 518, n. 1-2, p. 228-241, . (13/50181-1)
SIMIONI, ANDREZA RIBEIRO; CARVALHO DE JESUS, PRISCILA COSTA; TEDESCO, ANTONIO CLAUDIO. Layer-by-layer hollow photosensitizer microcapsule design via a manganese carbonate hard template for photodynamic therapy in cells. Photodiagnosis and Photodynamic Therapy, v. 22, p. 169-177, . (13/50181-1)
MONGE-FUENTES, VICTORIA; MAYER, ANDREIA BIOLCHI; LIMA, MARCOS ROBALINHO; GERALDES, LUIZA RIBEIRO; ZANOTTO, LARISSA NEPOMUCENO; MOREIRA, KARLA GRAZIELLA; MARTINS, OLIMPIA PASCHOAL; PIVA, HENRIQUE LUIS; SOARES FELIPE, MARIA SUELI; AMARAL, ANDRE CORREA; et al. Dopamine-loaded nanoparticle systems circumvent the blood-brain barrier restoring motor function in mouse model for Parkinson's Disease. SCIENTIFIC REPORTS, v. 11, n. 1, . (13/50181-1)
SOBRAL, V, DANIELLE; FUSCALDI, LEONARDO L.; DURANTE, ANA CLAUDIA R.; RANGEL, MAYARA G.; OLIVEIRA, LARISSA R.; MENDONCA, FERNANDA F.; MIRANDA, ANA CLAUDIA C.; CABEZA, JORGE M.; MONTOR, WAGNER R.; CABRAL, FRANCISCO R.; et al. Radiochemical and biological properties of peptides designed to interact with EGF receptor: Relevance for glioblastoma. NUCLEAR MEDICINE AND BIOLOGY, v. 88-89, p. 14-23, . (13/50181-1)
CALORI, ITALO RODRIGO; JAYME, CRISTIANO CERON; UENO, LEONARDO TSUYOSHI; CORRETO MACHADO, FRANCISCO BOLIVAR; TEDESCO, ANTONIO CLAUDIO. Theoretical and experimental studies concerning monomer/aggregates equilibrium of zinc phthalocyanine for future photodynamic action. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, v. 214, p. 513-521, . (18/10237-1, 13/50181-1)
REZENDE, NAYARA; JAYME, CRISTIANO CERON; BRASSESCO, MARIA SOL; TEDESCO, ANTONIO CLAUDIO; DE OLIVEIRA, HARLEY FRANCISCO. Standardization of a resazurin-based assay for the evaluation of metabolic activity in oral squamous carcinoma and glioblastoma cells. Photodiagnosis and Photodynamic Therapy, v. 26, p. 371-374, . (18/10237-1, 13/50181-1, 14/09421-1)
CALORI, ITALO RODRIGO; TEDESCO, ANTONIO CLAUDIO. Aluminum chloride phthalocyanine in MCF-7: Rationally accounting for state of aggregation of photosensitizers inside cells. DYES AND PIGMENTS, v. 173, . (13/50181-1)
SOUZA, CARLA; JAYME, CRISTIANO CERON; REZENDE, NAYARA; TEDESCO, ANTONIO CLAUDIO. Synergistic effect of photobiomodulation and phthalocyanine photosensitizer on fibroblast signaling responses in an in vitro three-dimensional microenvironment. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, v. 222, . (13/50181-1, 18/10237-1, 17/01272-5)
CURYLOFO-ZOTTI, FABIANA ALMEIDA; OLIVEIRA, VIVIANE DE CASSIA; MARCHESIN, ANALU RODRIGUEZ; BORGES, HIAGO SALGE; TEDESCO, ANTONIO CLAUDIO; CORONA, SILMARA APARECIDA MILORI. In vitro antibacterial activity of green tea-loaded chitosan nanoparticles on caries-related microorganisms and dentin after Er:YAG laser caries removal. Lasers in Medical Science, v. 38, n. 1, p. 8-pg., . (13/50181-1, 18/23862-1, 17/11582-1, 17/00720-4, 19/04807-2)
JAYME, CRISTIANO CERON; PIRES, ANANDA FERREIRA; FERNANDES, DANIELA SILVESTRINI; BI, HONG; TEDESCO, ANTONIO CLAUDIO. DNA polymer films used as drug delivery systems to early-stage diagnose and treatment of breast cancer using 3D tumor spheroids as a model. Photodiagnosis and Photodynamic Therapy, v. 37, p. 12-pg., . (18/10237-1, 13/50181-1)
CALORI, ITALO RODRIGO; BRAGA, GUSTAVO; CARVALHO DE JESUS, PRISCILA DA COSTA; BI, HONG; TEDESCO, ANTONIO CLAUDIO. Polymer scaffolds as drug delivery systems. EUROPEAN POLYMER JOURNAL, v. 129, . (13/50181-1)
DE MELO, MARYANNE TRAFANI; PIVA, HENRIQUE LUIS; TEDESCO, ANTONIO CLAUDIO. Design of new protein drug delivery system (PDDS) with photoactive compounds as a potential application in the treatment of glioblastoma brain cancer. Materials Science & Engineering C-Materials for Biological Applications, v. 110, . (13/50181-1)
JAYME, CRISTIANO CERON; CALORI, ITALO RODRIGO; FREIRE CUNHA, ELISE MARQUES; TEDESCO, ANTONIO CLAUDIO. Evaluation of aluminum phthalocyanine chloride and DNA interactions for the design of an advanced drug delivery system in photodynamic therapy. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, v. 201, p. 242-248, . (13/50181-1)
PELLOSI, DIOGO SILVA; CARVALHO DE JESUS, PRISCILA DA COSTA; TEDESCO, ANTONIO CLAUDIO. Spotlight on the delivery of photosensitizers: different approaches for photodynamic-based therapies. Expert Opinion on Drug Delivery, v. 14, n. 12, p. 1395-1406, . (13/50181-1)
TEDESCO, ANTONIO CLAUDIO; SILVA, EMANOEL P. O.; JAYME, CRISTIANO C.; PIVA, HENRIQUE L.; FRANCHI, LEONARDO P.. Cholesterol-rich nanoemulsion (LDE) as a novel drug delivery system to diagnose, delineate, and treat human glioblastoma. Materials Science & Engineering C-Materials for Biological Applications, v. 123, . (12/25216-3, 18/10237-1, 13/50181-1, 14/11870-9)
VENDETTE, ANTONIO CARLOS FIGUEIREDO; PIVA, HENRIQUE LUIS; MUEHLMANN, LUIS ALEXANDRE; DE SOUZA, DELFRANK ANANIAS; TEDESCO, ANTONIO CLAUDIO; AZEVEDO, RICARDO BENTES. Clinical treatment of intra-epithelia cervical neoplasia with photodynamic therapy. INTERNATIONAL JOURNAL OF HYPERTHERMIA, v. 37, n. 3, p. 9-pg., . (13/50181-1)
CALORI, ITALO RODRIGO; PIVA, HENRIQUE LUIS; TEDESCO, ANTONIO CLAUDIO. Targeted cancer therapy using alpha-cyano-4-hydroxycinnamic acid as a novel vector molecule: A proof-of-concept study. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, v. 57, . (13/50181-1)
OLIVEIRA, P. M.; LOPES, T. Z.; TEDESCO, A. C.; RAHAL, P.; CALMON, M. F.. Effect of berberine associated with photodynamic therapy in cell lines. Photodiagnosis and Photodynamic Therapy, v. 32, . (13/50181-1, 15/16660-5)
CABRAL, AGATA SILVA; RIVAS LEONEL, ELLEN CRISTINA; CANDIDO, NATALIA MARIA; PIVA, HENRIQUE LUIS; DE MELO, MARYANNE TRAFANI; TABOGA, SEBASTIAO ROBERTO; RAHAL, PAULA; TEDESCO, ANTONIO CLAUDIO; CALMON, MARILIA FREITAS. Combined photodynamic therapy with chloroaluminum phthalocyanine and doxorubicin nanoemulsions in breast cancer model. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, v. 218, . (20/04009-6, 13/50181-1)
GUSMAO, LUIZA ARAUJO; MATSUO, FLAVIA SAYURI; BARBOSA, HELLEN FRANCIANE GONCALVES; TEDESCO, ANTONIO CLAUDIO. Advances in nano-based materials for glioblastoma multiforme diagnosis: A mini-review. FRONTIERS IN NANOTECHNOLOGY, v. 4, p. 14-pg., . (13/50181-1, 18/17911-0)
FRANCHI, LEONARDO PEREIRA; BARBOSA DE FREITAS LIMA, JESSICA ELLEN; PIVA, HENRIQUE LUIS; TEDESCO, ANTONIO CLAUDIO. The redox function of apurinic/apyrimidinic endonuclease 1 as key modulator in photodynamic therapy. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, v. 211, p. 13-pg., . (17/14630-7, 13/50181-1, 14/11870-9)
MONICO, DANIELLI AZEVEDO; CALORI, ITALO RODRIGO; SOUZA, CARLA; ESPREAFICO, ENILZA MARIA; BI, HONG; TEDESCO, ANTONIO CLAUDIO. Melanoma spheroid-containing artificial dermis as an alternative approach to in vivo models. Experimental Cell Research, v. 417, n. 1, p. 11-pg., . (20/04507-6, 13/50181-1, 17/01272-5)
BARBOSA, HELLEN FRANCIANE GONCALVES; PIVA, HENRIQUE LUIS; MATSUO, FLAVIA SAYURI; DE LIMA, SARAH CAROLINE GOMES; DE SOUZA, LUCAS EDUARDO BOTELHO; OSAKO, MARIANA KIOMY; TEDESCO, ANTONIO CLAUDIO. Hybrid lipid-biopolymer nanocarrier as a strategy for GBM photodynamic therapy (PDT). International Journal of Biological Macromolecules, v. 242, p. 14-pg., . (18/17911-0, 13/50181-1, 20/04009-6)
BORGES, HIAGO SALGE; GUSMAO, LUIZA ARAUJO; TEDESCO, ANTONIO CLAUDIO. Multi-charged nanoemulsion for photodynamic treatment of glioblastoma cell line in 2D and 3D in vitro models. Photodiagnosis and Photodynamic Therapy, v. 43, p. 12-pg., . (13/50181-1)
FERREIRA-SILVA, VALERIA; PRIMO, FERNANDO L.; BAQUI, MUNIRA M. A.; MAGALHAES, DANIELLE A. R.; ORELLANA, MARISTELA D.; CASTILHO-FERNANDES, ANDRIELLE; CRUZ, MARIO C.; CAMARA, NIEHLS O. S.; COVAS, DIMAS T.; TEDESCO, ANTONIO C.. Beneficial Role of Low-Intensity Laser Irradiation on Neural beta-tubulin III Protein Expression in Human Bone Marrow Multipotent Mesenchymal Stromal Cells. STEM CELL REVIEWS AND REPORTS, v. 14, n. 4, p. 585-598, . (13/50181-1)
VENDETTE, ANTONIO CARLOS FIGUEIREDO; PIVA, HENRIQUE LUIS; MUEHLMANN, LUIS ALEXANDRE; DE SOUZA, DELFRANK ANANIAS; TEDESCO, ANTONIO CLAUDIO; AZEVEDO, RICARDO BENTES. Clinical treatment of intra-epithelia cervical neoplasia with photodynamic therapy. INTERNATIONAL JOURNAL OF HYPERTHERMIA, v. 37, n. 3, SI, p. 50-58, . (13/50181-1)
FERREIRA PIRES, ANANDA. Development of DNA polymer films as a drug delivery system for the treatment of oral cancer. DRUG DELIVERY AND TRANSLATIONAL RESEARCH, v. 10, n. 6, SI, . (13/50181-1, 18/10237-1)
LEANDRO, FERNANDA Z.; MARTINS, JULIA; FONTES, APARECIDA M.; TEDESCO, ANTONIO C.. Evaluation of theranostic nanocarriers for near-infrared imaging and photodynamic therapy on human prostate cancer cells. COLLOIDS AND SURFACES B-BIOINTERFACES, v. 154, p. 341-349, . (13/50181-1, 08/53719-4)
SILVA, E. P. O.; FRANCHI, L. P.; TEDESCO, A. C.. Chloro-aluminium phthalocyanine loaded in ultradeformable liposomes for photobiology studies on human glioblastoma. RSC ADVANCES, v. 6, n. 83, p. 79631-79640, . (12/25216-3, 13/50181-1, 14/11870-9)
CALORI, ITALO RODRIGO; TEDESCO, ANTONIO CLAUDIO. Lipid vesicles loading aluminum phthalocyanine chloride: Formulation properties and disaggregation upon intracellular delivery. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, v. 160, p. 240-247, . (13/50181-1)
DE PAULA, L. B.; PRIMO, F. L.; PINTO, M. R.; MORAIS, P. C.; TEDESCO, A. C.. Evaluation of a chloroaluminium phthalocyanine-loaded magnetic nanoemulsion as a drug delivery device to treat glioblastoma using hyperthermia and photodynamic therapy. RSC ADVANCES, v. 7, n. 15, p. 9115-9122, . (15/18684-9, 13/50181-1)
CALORI, ITALO RODRIGO; BI, HONG; TEDESCO, ANTONIO CLAUDIO. Expanding the Limits of Photodynamic Therapy: The Design of Organelles and Hypoxia-Targeting Nanomaterials for Enhanced Photokilling of Cancer. ACS APPLIED BIO MATERIALS, v. 4, n. 1, p. 195-228, . (20/06523-9, 13/50181-1)
PELLOSI, DIOGO SILVA; MACAROFF, PATRICIA PEREIRA; MORAIS, PAULO CESAR; TEDESCO, ANTONIO CLAUDIO. Magneto low-density nanoemulsion (MLDE): A potential vehicle for combined hyperthermia and photodynamic therapy to treat cancer selectively. Materials Science & Engineering C-Materials for Biological Applications, v. 92, p. 103-111, . (15/18684-9, 16/00389-3, 13/50181-1)
SALLES DE OLIVEIRA, DAPHNE CHRISTINE; DE FREITAS, CAMILA FABIANO; CALORI, ITALO RODRIGO; GONCALVES, RENATO SONCHINI; ERRERIAS FERNANDES CARDINALI, CAMILA APARECIDA; MALACARNE, LUIS CARLOS; RAVANELLI, MARIA IDA; DE OLIVEIRA, HUEDER PAULO MOISES; TEDESCO, ANTONIO CLAUDIO; CAETANO, WILKER; et al. Theranostic verteporfin- loaded lipid-polymer liposome for photodynamic applications. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, v. 212, . (13/50181-1)
CASTILHO-FERNANDES, ANDRIELLE; LOPES, TACILA G.; PRIMO, FERNANDO L.; PINTO, MARCELO R.; TEDESCO, ANTONIO C.. Photodynamic process induced by chloro-aluminum phthalocyanine nanoemulsion in glioblastoma. Photodiagnosis and Photodynamic Therapy, v. 19, p. 221-228, . (13/50181-1, 16/21504-5)
FRANCHI, LEONARDO PEREIRA; AMANTINO, CAMILA F.; MELO, MARYANNE T.; DE LIMA MONTALDI, ANA PAULA; PRIMO, FERNANDO L.; TEDESCO, ANTONIO CLAUDIO. In vitro effects of photodynamic therapy induced by chloroaluminum phthalocyanine nanoemulsion. Photodiagnosis and Photodynamic Therapy, v. 16, p. 100-105, . (13/50181-1, 14/11870-9)
CALORI, ITALO RODRIGO; ALVES, SAMARA RODRIGUES; BI, HONG; TEDESCO, ANTONIO CLAUDIO. Type-I Collagen/Collagenase Modulates the 3D Structure and Behavior of Glioblastoma Spheroid Models. ACS APPLIED BIO MATERIALS, v. 5, n. 2, p. 11-pg., . (20/04507-6, 13/50181-1)
UNTEN TAKAHASHI, LUANDRA APARECIDA; MILORI CORONA, SILMARA APARECIDA. Conjugate of chitosan nanoparticles with chloroaluminium phthalocyanine: Synthesis, characterization and photoinactivation of Streptococcus mutans biofilm. Photodiagnosis and Photodynamic Therapy, v. 30, . (13/50181-1, 19/05965-0)
DE ANDRADE, LAISE R.; TEDESCO, ANTONIO C.; PRIMO, FERNANDO L.; FARIAS, GABRIEL R.; DA SILVA, JAQUELINE R.; LONGO, JOAO P. F.; DE ALMEIDA, MARCOS C.; DE SOUZA, PAULO E. N.; DE AZEVEDO, RICARDO B.; PINHEIRO, WILLIE O.; et al. Tumor cell death in orthotopic breast cancer model by NanoALA: a novel perspective on photodynamic therapy in oncology. Nanomedicine, v. 15, n. 10, p. 1019-1036, . (13/50181-1)
FERREIRA-SILVA, VALERIA; PRIMO, FERNANDO L.; BAQUI, MUNIRA M. A.; MAGALHAES, DANIELLE A. R.; ORELLANA, MARISTELA D.; CASTILHO-FERNANDES, ANDRIELLE; CRUZ, MARIO C.; CAMARA, NIEHLS O. S.; COVAS, DIMAS T.; TEDESCO, ANTONIO C.. Beneficial Role of Low-Intensity Laser Irradiation on Neural beta-tubulin III Protein Expression in Human Bone Marrow Multipotent Mesenchymal Stromal Cells. STEM CELL REVIEWS AND REPORTS, v. 14, n. 4, p. 14-pg., . (13/50181-1)
CURYLOFO-ZOTTI, FABIANA ALMEIDA; TEDESCO, ANTONIO CLAUDIO; LIZARELLI, GUSTAVO TEODORO COSTA; TAKAHASHI, LUANDRA APARECIDA UNTEN; CORONA, SILMARA APARECIDA MILORI. Effect of green tea-loaded chitosan nanoparticles on leathery dentin microhardness. ODONTOLOGY, v. 109, n. 4, p. 8-pg., . (17/11582-1, 13/50181-1, 19/04807-2)
CERON JAYME, CRISTIANO; FERREIRA PIRES, ANANDA; TEDESCO, ANTONIO CLAUDIO. Development of DNA polymer films as a drug delivery system for the treatment of oral cancer. DRUG DELIVERY AND TRANSLATIONAL RESEARCH, v. 10, n. 6, p. 14-pg., . (18/10237-1, 13/50181-1)
CALORI, ITALO RODRIGO; PINHEIRO, LUKAS; BRAGA, GUSTAVO; PEDROSO DE MORAIS, FLAVIA AMANDA; CAETANO, WILKER; TEDESCO, ANTONIO CLAUDIO; HIOKA, NOBORU. Interaction of triblock copolymers (Pluronic (R)) with DMPC vesicles: a photophysical and computational study. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, v. 275, p. 10-pg., . (20/04507-6, 13/50181-1)
CALORI, ITALO RODRIGO; BRAGA, GUSTAVO; TESSARO, ANDRE LUIZ; CAETANO, WILKER; TEDESCO, ANTONIO CLAUDIO; HIOKA, NOBORU. Self-aggregation of the proteolytic forms of Verteporfin: An in silico and in vitro study. JOURNAL OF MOLECULAR LIQUIDS, v. 352, p. 9-pg., . (20/04507-6, 13/50181-1)
GOBO, GRACIELY GOMIDES; PIVA, HENRIQUE LUIS; TEDESCO, ANTONIO CLAUDIO; PRIMO, FERNANDO LUCAS. Novel quinizarin spray-dried nanoparticles for treating melanoma with photodynamic therapy. MATERIALS TODAY COMMUNICATIONS, v. 33, p. 9-pg., . (13/50181-1, 20/04009-6)
JAYME, CRISTIANO CERON; REZENDE, NAYARA; FERNANDES, DANIELA S. .; PAULA, LEONARDO B. DE; DE CASTRO, BARBARA GIMENES; TAKAHASHI, LUANDRA APARECIDA U. .; TEDESCO, ANTONIO CLAUDIO. Target selectivity of cholesterol-phosphatidylcholine liposome loaded with phthalocyanine for breast cancer diagnosis and treatment by photodynamic therapy. Photodiagnosis and Photodynamic Therapy, v. 39, p. 6-pg., . (18/24004-9, 21/02207-8, 18/10237-1, 15/18684-9, 13/50181-1)
JAYME, CRISTIANO CERON; SOUZA, CARLA; FERNANDES, DANIELA SILVESTRINI; TEDESCO, ANTONIO CLAUDIO. Tailoring the growth and proliferation of human dermal fibroblasts by DNA-based polymer films for skin regeneration. Journal of Biomedical Materials Research Part A, v. 109, n. 11, p. 2381-2391, . (17/01272-5, 18/10237-1, 13/50181-1)
JAYME, CRISTIANO CERON; DE PAULA, LEONARDO BARCELOS; REZENDE, NAYARA; CALORI, ITALO RODRIGO; FRANCHI, LEONARDO PEREIRA; TEDESCO, ANTONIO CLAUDIO. DNA polymeric films as a support for cell growth as a new material for regenerative medicine: Compatibility and applicability. Experimental Cell Research, v. 360, n. 2, p. 404-412, . (15/18684-9, 13/50181-1, 14/11870-9)
SOUZA, CARLA; MONICO, DANIELLI AZEVEDO; TEDESCO, ANTONIO CLAUDIO. Implications of dichlorofluorescein photoinstability for detection of UVA-induced oxidative stress in fibroblasts and keratinocyte cells. PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES, v. 19, n. 1, p. 40-48, . (13/50181-1, 17/01272-5)
SOUZA, CARLA; PELLOSI, DIOGO SILVA; TEDESCO, ANTONIO CLAUDIO. Prodrugs for targeted cancer therapy. EXPERT REVIEW OF ANTICANCER THERAPY, v. 19, n. 6, p. 483-502, . (16/00389-3, 13/50181-1, 17/01272-5)
PELLOSI, DIOGO S.; PAULA, LEONARDO B.; DE MELO, MARYANNE T.; TEDESCO, ANTONIO C.. Targeted and Synergic Glioblastoma Treatment: Multifunctional Nanoparticles Delivering Verteporfin as Adjuvant Therapy for Temozolomide Chemotherapy. MOLECULAR PHARMACEUTICS, v. 16, n. 3, p. 1009-1024, . (13/50181-1, 16/00389-3, 18/24004-9, 15/18684-9)
CASTILHO-FERNANDES, ANDRIELLE; LOPES, TADLA G.; FERREIRA, FERNANDO U.; REZENDE, NAYARA; SILVA, VALERIA F.; PRIMO, FERNANDO L.; FONTES, APARECIDA MARIA; RIBEIRO-SILVA, ALFREDO; TEDESCO, ANTONIO CLAUDIO. Adipogenic differentiation of murine bone marrow mesenchymal stem cells induced by visible light via photo- induced biomodulation. Photodiagnosis and Photodynamic Therapy, v. 25, p. 119-127, . (13/50181-1)
ALVES, SAMARA RODRIGUES; CALORI, ITALO RODRIGO; TEDESCO, ANTONIO CLAUDIO. Photosensitizer-based metal-organic frameworks for highly effective photodynamic therapy. Materials Science & Engineering C-Materials for Biological Applications, v. 131, . (20/04507-6, 13/50181-1)
RIBEIRO CAVALCANTE, LEONARDO LOBO; TEDESCO, ANTONIO CLAUDIO; SOUZA-GABRIEL, ALINE EVANGELISTA; BORGES, HIAGO SALGE; CURYLOFO-ZOTTI, FABIANA ALMEIDA; MILORI CORONA, SILMARA APARECIDA. Photoinactivation of multispecies cariogenic biofilm mediated by aluminum phthalocyanine chloride encapsulated in chitosan nanoparticles. Lasers in Medical Science, . (13/50181-1, 19/05965-0)
DA SILVA, DARLAN BARBOSA; DA SILVA, CAROLINA LOUREIRO; DAVANZO, NATHALIA NOSSI; SOUZA, RODRIGO DA SILVA; CORREA, RODRIGO JOSE; TEDESCO, ANTONIO CLAUDIO; RIEMMA PIERRE, MARIA BERNADETE. Protoporphyrin IX (PpIX) loaded PLGA nanoparticles for topical Photodynamic Therapy of melanoma cells. Photodiagnosis and Photodynamic Therapy, v. 35, . (13/50181-1, 15/16660-5)
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