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Production and environmental application of y-polyglutamic acid by cultivation of B. subtilis in soy substrate

Grant number: 15/02650-8
Support Opportunities:Regular Research Grants
Start date: August 01, 2015
End date: July 31, 2017
Field of knowledge:Engineering - Sanitary Engineering - Water Supply and Wastewater Treatment
Principal Investigator:Valquiria de Campos
Grantee:Valquiria de Campos
Host Institution: Instituto de Ciência e Tecnologia. Universidade Estadual Paulista (UNESP). Campus de Sorocaba. Sorocaba , SP, Brazil
Associated researchers: Isaac Jamil Sayeg ; Nilton Pereira Alves

Abstract

³-polyglutamic acid (³-PGA) is a water soluble biodegradable anionic biopolymer that is edible and non-toxic to humans and the environment. Due to these special characteristics, it has been applied in the environmental sector. ³-PGA is naturally present in the mucilage of fermented soy products consumed in Asian countries; therefore, soy and its derivatives are potential substrates for the production of this biopolymer. The use of ³-PGA in water treatment increases its flocculation activity, among other properties. This work focuses on the production of ³-PGA using soybeans fermented with Bacillus subtilis var. natto. The specific objectives of this study are the development of a new formulation through a combination with other reagents, and to evaluate different coagulants (³-PGA and Poly-glu) in the process of coagulation-flocculation and separation of solids from the liquid phase by sedimentation. The new formulation will be compared with the commercial product Poly-Glu (Nippon Poly-Glu), which is reportedly effective in the decontamination of water for human consumption. To test with of the new formulation and others coagulants, quality assays will be performed in water from the Billings Complex, Rio Grande, which is one of the largest and most important water reservoirs in the metropolitan region of São Paulo. (AU)

Articles published in Agência FAPESP Newsletter about the research grant:
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VEICULO: TITULO (DATA)
VEICULO: TITULO (DATA)

Scientific publications (7)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
CAMPOS, VALQUIRIA; FERNANDES, ANA R. A. C.; MEDEIROS, THALES. A. M.; ANDRADE, ERIK L.. Physicochemical characterization and evaluation of PGA bioflocculant in coagulation-flocculation and sedimentation processes. JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING, v. 4, n. 4, A, p. 3753-3760, . (15/02650-8)
CAMPOS, V.; KASPARY, R. M.; ROSSI, M. J.; MEDEIROS, T. A. M.. iosynthesis of gamma-Polyglutamic Acid by Bacillus licheniformis Through Submerged Fermentation (SmF) and Solid-state Fermentation (SSF. CHEMICAL AND BIOCHEMICAL ENGINEERING QUARTERLY, v. 35, n. 3, p. 333-344, . (15/02650-8)
CAMPOS, V; PIMENTEL FILHO, N. J.; MEDEIROS, T. A. M.. Study of Bacillus spp. strains used in the production of gamma-polyglutamic acid in submerged culture. INTERNATIONAL FOOD RESEARCH JOURNAL, v. 27, n. 3, p. 427-434, . (15/02650-8)
FERNANDES, ANA ROSA AON CARDOSO; SGANZERLA, WILLIAM GUSTAVO; GRANADO, NILTON PEREIRA ALVES; CAMPOS, VALQUIRIA. Implication of organic solvents in the precipitation of ?-polyglutamic acid for application as a sustainable flocculating agent. BIOCATALYSIS AND AGRICULTURAL BIOTECHNOLOGY, v. 50, p. 9-pg., . (15/02650-8)
CAMPOS, V.; MORAIS, L. C.; MAFAVISSE, I. M.. Synthesis of a Plant-based Dust Suppressant and Testing on Coal from Moatize, Mozambique. CHEMICAL AND BIOCHEMICAL ENGINEERING QUARTERLY, v. 36, n. 3, p. 9-pg., . (15/02650-8)
CAMPOS, VALQUIRIA; DOMINGOS, JANAINA M. F.; DOS ANJOS, DIEGO N.; LIRA, VIVIAN S.. Study of fluvial water treatability using gamma-polyglutamic acid based biopolymer coagulant. Anais da Academia Brasileira de Ciências, v. 91, n. 3, . (15/02650-8)
CAMPOS, VALQUIRIA; FERNANDES, ANA R. A. C.; MEDEIROS, THALES. A. M.; ANDRADE, ERIK L.. Physicochemical characterization and evaluation of PGA bioflocculant in coagulation-flocculation and sedimentation processes. JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING, v. 4, n. 4, p. 8-pg., . (15/02650-8)