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Production and environmental application of y-polyglutamic acid by cultivation of B. subtilis in soy substrate

Grant number: 15/02650-8
Support type:Regular Research Grants
Duration: August 01, 2015 - July 31, 2017
Field of knowledge:Engineering - Sanitary Engineering - Water Supply and Wastewater Treatment
Principal researcher:Valquiria de Campos
Grantee:Valquiria de Campos
Home Institution: Instituto de Ciência e Tecnologia. Universidade Estadual Paulista (UNESP). Campus de Sorocaba. Sorocaba , SP, Brazil
Assoc. researchers: Isaac Jamil Sayeg ; Nilton Pereira Alves


³-polyglutamic acid (³-PGA) is a water soluble biodegradable anionic biopolymer that is edible and non-toxic to humans and the environment. Due to these special characteristics, it has been applied in the environmental sector. ³-PGA is naturally present in the mucilage of fermented soy products consumed in Asian countries; therefore, soy and its derivatives are potential substrates for the production of this biopolymer. The use of ³-PGA in water treatment increases its flocculation activity, among other properties. This work focuses on the production of ³-PGA using soybeans fermented with Bacillus subtilis var. natto. The specific objectives of this study are the development of a new formulation through a combination with other reagents, and to evaluate different coagulants (³-PGA and Poly-glu) in the process of coagulation-flocculation and separation of solids from the liquid phase by sedimentation. The new formulation will be compared with the commercial product Poly-Glu (Nippon Poly-Glu), which is reportedly effective in the decontamination of water for human consumption. To test with of the new formulation and others coagulants, quality assays will be performed in water from the Billings Complex, Rio Grande, which is one of the largest and most important water reservoirs in the metropolitan region of São Paulo. (AU)

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Scientific publications (4)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
CAMPOS, V.; KASPARY, R. M.; ROSSI, M. J.; MEDEIROS, T. A. M. iosynthesis of gamma-Polyglutamic Acid by Bacillus licheniformis Through Submerged Fermentation (SmF) and Solid-state Fermentation (SSF. CHEMICAL AND BIOCHEMICAL ENGINEERING QUARTERLY, v. 35, n. 3, p. 333-344, 2021. Web of Science Citations: 0.
CAMPOS, V; PIMENTEL FILHO, N. J.; MEDEIROS, T. A. M. Study of Bacillus spp. strains used in the production of gamma-polyglutamic acid in submerged culture. INTERNATIONAL FOOD RESEARCH JOURNAL, v. 27, n. 3, p. 427-434, JUN 2020. Web of Science Citations: 0.
CAMPOS, VALQUIRIA; DOMINGOS, JANAINA M. F.; DOS ANJOS, DIEGO N.; LIRA, VIVIAN S. Study of fluvial water treatability using gamma-polyglutamic acid based biopolymer coagulant. Anais da Academia Brasileira de Ciências, v. 91, n. 3 2019. Web of Science Citations: 0.
CAMPOS, VALQUIRIA; FERNANDES, ANA R. A. C.; MEDEIROS, THALES. A. M.; ANDRADE, ERIK L. Physicochemical characterization and evaluation of PGA bioflocculant in coagulation-flocculation and sedimentation processes. JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING, v. 4, n. 4, A, p. 3753-3760, DEC 2016. Web of Science Citations: 4.

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