Multi-User Equipment approved in grant 2014/17526-8: electron paramagnetic resonance (EPR) spectrometer - X band

• Grant number: 15/11759-3
• Support type: Multi-user Equipment Program
• Duration: September 01, 2015 - August 31, 2017
• Field of knowledge: Engineering - Biomedical Engineering - Bioengineering
• Principal Investigator: Rondinelli Donizetti Herculano
• Grantee: Rondinelli Donizetti Herculano
• Home Institution: Faculdade de Ciências Farmacêuticas (FCFAR). Universidade Estadual Paulista (UNESP). Campus de Araraquara. Araraquara , SP, Brazil
• Associated research grant: 14/17526-8 - Development of a novel system employing natural rubber latex as releasing of vegetable extracts incorporated with nanoparticles: physical chemical and biological characterization, AP.R
• EMU web page: Página do Equipamento Multiusuário não informada
• Tipo de equipamento: Caracterização de Materiais - Espectroscopia - EPR (ressonância eletrônica)
• Fabricante: Fabricante não informado
• Modelo: Modelo não informado

Abstract

Multi-User Equipment approved in grant 2014/17526-8: Electron Paramagnetic Resonance (EPR) spectrometer - X Band is the most straightforward-to-use technique for studying free radicals and other paramagnetic species and has therefore established itself in biomedical research and for clinical applications. In additional, this technique also have been extensively employed in many areas in physics, chemistry and biology. The basic concepts of EPR are analogous to those of nuclear magnetic resonance (NMR), but it is electron spins that are excited instead of the spins of atomic nuclei. EPR spectroscopy is particularly useful for studying metal complexes or organic radicals. EPR found its applications for investigations on the structures of this protein aggregates, but also of other proteins or protein complexes with medical relevance the technique of site-directed spin labeling (SDSL) - the site- specific introduction of paramagnetic reporter groups into proteins or nucleic acids - is nowadays frequently used, especially in cases where other structural techniques are not. Moreover, by direct detection of free radicals - also in combination with spin trapping methods, or application of SDSL, EPR spectroscopy can be also used for diagnostic purposes, e.g. in cancer diagnostics. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

ZANCANELA, DANIELA CERVELLE; FUNARI, CRISTIANO SOLEO; HERCULANO, RONDINELLI DONIZETTI; MELLO, VINICIUS MOREIRA; RODRIGUES, CLENILSON MARTINS; BORGES, FELIPE AZEVEDO; DE BARROS, NATAN ROBERTO; MARCOS, CAROLINE MARIA; FUSCO ALMEIDA, ANA MARISA; GUASTALDI, ANTONIO CARLOS. Natural rubber latex membranes incorporated with three different types of propolis: Physical-chemistry and antimicrobial behaviours. Materials Science & Engineering C-Materials for Biological Applications, v. 97, p. 576-582, APR 2019. Web of Science Citations: 3.

DE BARROS, NATAN ROBERTO; HEREDIA-VIEIRA, SILVIA CRISTINA; BORGES, FELIPE AZEVEDO; BENITES, NIKOLLAS MOREIRA; DOS REIS, CAMILA EUGENIA; ROMEIRO MIRANDA, MATHEUS CARLOS; LIMA CARDOSO, CLAUDIA ANDREA; HERCULANO, RONDINELLI DONIZETTI. Natural rubber latex biodevice as controlled release system for chronic wounds healing. BIOMEDICAL PHYSICS & ENGINEERING EXPRESS, v. 4, n. 3 MAY 2018. Web of Science Citations: 1.