Endovenous iron versus oral iron for acute postoperative anemia treatment in patientes undergoing abdominoplasty after bariatric surgery: multicenter randomized clinical trial

• Grant number: 14/07710-6
• Support Opportunities: Regular Research Grants
• Start date: October 01, 2015
• End date: September 30, 2017
• Field of knowledge: Health Sciences - Medicine - Surgery
• Principal Investigator: Lydia Masako Ferreira
• Grantee: Lydia Masako Ferreira
• Host Institution: Escola Paulista de Medicina (EPM). Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. São Paulo , SP, Brazil
• Associated researchers: Elvio Bueno Garcia ; Juan Carlos Montano Pedroso

Abstract

Patients undergoing bariatric surgery to treat morbid obesity develop a series of deformities of body contouring after major weight loss, especially in the abdomen region. Such excess skin and adiposity can be treated by post-bariatric abdominoplasty.However, post-bariatric patients, especially adult women, have a tendency to iron deficiency and anemia. Iron deficiency is primarily caused by reductions in iron ingestion, gastric acid secretion, and reduced contact of food with the iron-absorptive area of the diverted duodenal and jejunal segments of the gastrointestinal tract because of deviations caused by bariatric surgery. Anemia is the second most frequent complication after post-bariatric abdominoplasty. MONTANO-PEDROSO et al. (2012) demonstrated that 45% of patients evolve with iron deficiency after post-bariatric abdominoplasty and at 8 postoperative weeks the patients had not recovered their preoperative hemoglobin levels. A deficiency of iron, in turn, can cause symptoms of fatigue and contribute to anemia.On the other hand, administration of intravenous iron proved to be an effective and safe way to increase hemoglobin levels in surgical patients. However, the authors of this study didn't found any research about the effectiveness of intravenous iron in improving symptoms of fatigue or anemia in patients undergoing post-bariatric plastic surgery. The aim of this study is to evaluate the efficacy of intravenous iron in the treatment of fatigue and recovery from post-operative anemia in patients undergoing abdominoplasty after bariatric surgery through a randomized controlled trial. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

MONTANO-PEDROSO, JUAN CARLOS; GARCIA, ELVIO BUENO; NOVO, NEIL FERREIRA; VEIGA, DANIELA FRANCESCATO; FERREIRA, LYDIA MASAKO. Postoperative intravenously administered iron sucrose versus postoperative orally administered iron to treat post-bariatric abdominoplasty anaemia (ISAPA): the study protocol for a randomised controlled trial. Trials, v. 17, APR 12 2016. (14/07710-6)