Development and processing of Al2O3-ZrO2 translucent composite for CAD/CAM monolithic prostheses: the effect of aging on biaxial flexural strength

• Grant number: 12/19078-7
• Support type: Research Grants - Young Investigators Grants
• Duration: August 01, 2016 - July 31, 2020
• Field of knowledge: Health Sciences - Dentistry
• Principal Investigator: Estevam Augusto Bonfante
• Grantee: Estevam Augusto Bonfante
• Home Institution: Faculdade de Odontologia de Bauru (FOB). Universidade de São Paulo (USP). Bauru , SP, Brazil
• Assoc. researchers: Paulo Francisco Cesar
• Associated grant(s): 16/18818-8 - Multi-User Equipment approved in grant 2012/19078-7: ElectroPuls E3000 Linear-Torsion All-Electric dynamic test instrument package, AP.EMU
• Associated scholarship(s): 19/14798-0 - Development of pre-sintered ZTA 80% Al2O3/20% ZrO2 composite blocks for milling in CAD/CAM system, BP.DR; 19/15598-5 - Characterization of the resistance of an experimental ultra-translucent zirconia, BP.IC; 19/08693-1 - Experimental glass-infiltrated alumina-zirconia composites: characterization of microstructure, optical and mechanical properties, BP.PD; + associated scholarships 18/19094-9 - Experimental composits 80%ZrO2 -20%Al2O3: microstructural, optical and survivor characterization, BP.MS; 18/03072-6 - Experimental 70% Al2O3-30% ZrO2 composites: structural characterization and survival probability before and after aging, BP.DR; 16/24165-7 - Development and characterization of conventional ZTA composite mechanical properties for monolithic CAD / CAM prostheses, BP.IC; 16/18657-4 - Development and characterization of optical, topographic and crystalline phase properties of conventional ZTA composite for monolithic CAD/CAM prostheses, BP.IC; 16/17793-1 - Development and mechanical and optical characterization of 80% Al2O3 and 20% ZrO2 translucent composites for CAD/CAM monolithic prostheses, BP.MS - associated scholarships

Abstract

Although yttrium tetragonal zirconia polycrystals (Y-TZP) is a promising material, it lacks hydrothermal stability at low temperature due to the tetragonal to monoclinic phase transformation which can compromise its mechanical properties and hence its long-term predictability. This project aims to innovate in the synthesis of alumina-toughened-zirconia (ZTA) composites for dentistry that combines the best properties of both alumina and of zirconia yielding mechanical properties and hydrothermal stability to the oral environment. A method is proposed to synthesize ZTA composites with either a conventional zirconia powder or a translucent zirconia powder both to be compared with experimental translucent and conventional Y-TZP. Optical properties, phase transformation, and biaxial flexural strength will be characterized before and after an accelerated aging protocol. The benefits of this project include the fabrication of ZTA blocks for CAD/CAM that can be used as monolithic prostheses in minimally invasive preparations which preserve tooth structure and as a substructure for prostheses. This project is within the scope of what was originally proposed in JP FAPESP # 2012/19078-7 ("STEP-STRESS ACCELERATED LIFE TESTING AND FRACTOGRAPHY FOR RELIABILITY CHARACTERIZATION OF DENTAL IMPLANTS") that is aimed to nucleate at FOB a center for accelerated life testing and fractographic analysis to predict the reliability of implant-supported reconstructions and characterize their failure modes, thus enabling training and knowledge input in the field. This project comprises the synthesis and characterization of 2 ZTA composites and 2 experimental Y-TZP and subsequent testing would involve step-stress accelerated life testing and the methods described in Projeto Central and Projetos adjacentes (see Anexo 1_Projeto). From the first R1, this proposal includes several colaborating institutions that could benefit from the nucleated center both within and outside of SP. (AU)

Scientific publications

(22)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

BONFANTE, ESTEVAM A.; JIMBO, RYO; WITEK, LUKASZ; TOVAR, NICK; NEIVA, RODRIGO; TORRONI, ANDREA; COELHO, PAULO G. Biomaterial and biomechanical considerations to prevent risks in implant therapy. PERIODONTOLOGY 2000, v. 81, n. 1, p. 139-151, OCT 2019. Web of Science Citations: 0.

BENALCAZAR JALKH, E. B.; MACHADO, C. M.; GIANINNI, M.; BELTRAMINI, I; PIZA, M. M. T.; COELHO, P. G.; HIRATA, R.; BONFANTE, E. A. Effect of Thermocycling on Biaxial Flexural Strength of CAD/CAM, Bulk Fill, and Conventional Resin Composite Materials. Operative Dentistry, v. 44, n. 5, p. E254-E262, SEP-OCT 2019. Web of Science Citations: 1.

GRANATO, RODRIGO; BONFANTE, ESTEVAM A.; CASTELLANO, ARTHUR; KHAN, REHAN; JIMBO, RYO; MARIN, CHARLES; MORSI, SARA; WITEK, LUKASZ; COELHO, PAULO G. Osteointegrative and microgeometric comparison between micro-blasted and alumina blasting/acid etching on grade II and V titanium alloys (Ti-6Al-4V). JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS, v. 97, p. 288-295, SEP 2019. Web of Science Citations: 0.

BERGAMO, EDMARA T. P.; BORDIN, DIMORUAN; RAMALHO, ILANA S.; LOPES, ADOLFO C. O.; GOMES, RAFAEL S.; KAIZER, MARINA; WITEK, LULZASZ; BONFANTE, ESTEUAM A.; COELHO, PAULO G.; DEL BEL CURY, ALTAIR A. Zirconia-reinforced lithium silicate crowns: Effect of thickness on survival and failure mode. Dental Materials, v. 35, n. 7, p. 1007-1016, JUL 2019. Web of Science Citations: 0.

LOPES, A. C. O.; COELHO, P. G.; WITEK, L.; BENALCAZAR JALKH, E. B.; GENOVA, L. A.; MONTEIRO, K. N.; CESAR, P. F.; LISBOA FILHO, P. N.; BERGAMO, E. T. P.; RAMALHO, I. S.; BONFANTE, E. A. Nanomechanical and microstructural characterization of a zirconia-toughened alumina composite after aging. CERAMICS INTERNATIONAL, v. 45, n. 7, A, p. 8840-8846, MAY 2019. Web of Science Citations: 1.

LAHENS, BRADLEY; LOPEZ, CHRISTOPHER D.; NEIVA, RODRIGO F.; BOWERS, MICHELLE M.; JIMBO, RYO; BONFANTE, ESTEVAM A.; MORCOS, JONATHAN; WITEK, LUKASZ; TOVAR, NICK; COELHO, PAULO G. The effect of osseodensification drilling for endosteal implants with different surface treatments: A study in sheep. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, v. 107, n. 3, p. 615-623, APR 2019. Web of Science Citations: 0.

DE PAULA, VITOR GUARCONI; BONFANTE, GERSON; LORENZONI, FABIO C.; COELHO, PAULO G.; BONJARDIM, LEONARDO RIGOLDI; FARDIN, VINICIUS P.; BONFANTE, ESTEVAM A. Lifetime prediction of veneered versus monolithic lithium disilicate crowns loaded on marginal ridges. Dental Materials, v. 35, n. 3, p. 511-522, MAR 2019. Web of Science Citations: 1.

DE OLIVEIRA LOPES, ADOLFO COELHO; MACHADO, CAMILA MOREIRA; BONJARDIM, LEONARDO RIGOLDI; PEDROSO BERGAMO, EDMARA TATIELY; RAMALHO, ILANA SANTOS; WITEK, LUKASZ; COELHO, PAULO GUILHERME; BONFANTE, ESTEVAM AUGUSTO. The Effect of CAD/CAM Crown Material and Cement Type on Retention to Implant Abutments. JOURNAL OF PROSTHODONTICS-IMPLANT ESTHETIC AND RECONSTRUCTIVE DENTISTRY, v. 28, n. 2, p. E552-E556, FEB 2019. Web of Science Citations: 0.

DE OLIVEIRA LINO, LUCAS FRACASSI; MACHADO, CAMILA MOREIRA; DE PAULA, VITOR GUARCONI; VIDOTTI, HUGO ALBERTO; COELHO, PAULO G.; BENALCAZAR JALKH, ERNESTO BYRON; PEGORARO, THIAGO AMADEI; BONFANTE, ESTEVAM AUGUSTO. Effect of aging and testing method on bond strength of CAD/CAM fiber-reinforced composite to dentin. Dental Materials, v. 34, n. 11, p. 1690-1701, NOV 2018. Web of Science Citations: 0.

DE OLIVEIRA, PAULA G. F. PESSOA; BERGAMO, EDMARA T. P.; NEIVA, RODRIGO; BONFANTE, ESTEVAM A.; WITEK, LUKASZ; TOVAR, NICK; COELHO, PAULO G. Osseodensification outperforms conventional implant subtractive instrumentation: A study in sheep. Materials Science & Engineering C-Materials for Biological Applications, v. 90, p. 300-307, SEP 1 2018. Web of Science Citations: 2.

BORDIN, DIMORVAN; COELHO, PAULO G.; BERGAMO, EDMARA T. P.; BONFANTE, ESTEVAM A.; WITEK, LUKASZ; DEL BEL CURY, ALTAIR A. The effect of DLC-coating deposition method on the reliability and mechanical properties of abutment's screws. Dental Materials, v. 34, n. 6, p. E128-E137, JUN 2018. Web of Science Citations: 1.

BARBOSA, JOAO MALTA; DA ROCHA, DANIEL NAVARRO; HIRATA, RONALDO; FREITAS, GILEADE; BONFANTE, ESTEVAM A.; COELHO, PAULO G. Fatigue Failure of External Hexagon Connections on Cemented Implant-Supported Crowns. IMPLANT DENTISTRY, v. 27, n. 2, p. 165-170, APR 2018. Web of Science Citations: 0.

ARAUJO LEMOS, CLEIDIEL APARECIDO; VERRI, FELLIPPO RAMOS; BONFANTE, ESTEVAM AUGUSTO; SANTIAGO JUNIOR, JOEL FERREIRA; PELLIZZER, EDUARDO PIZA. Comparison of external and internal implant-abutment connections for implant supported prostheses. A systematic review and meta-analysis. Journal of Dentistry, v. 70, p. 14-22, MAR 2018. Web of Science Citations: 9.

FARDIN, VINICIUS P.; BONFANTE, ESTEVAM A.; COELHO, PAULO G.; JANAL, MALVIN N.; TOVAR, NICK; WITEK, LUKASZ; BORDIN, DIMORVAN; BONFANTE, GERSON. Residual stress of porcelain-fused to zirconia 3-unit fixed dental prostheses measured by nanoindentation. Dental Materials, v. 34, n. 2, p. 260-271, FEB 2018. Web of Science Citations: 3.

ANCHIETA, RODOLFO B.; GUIMARAES, MARCIA V. M.; SUZUKI, MARCELO; TOVAR, NICK; BONFANTE, ESTEVAM A.; ATRIA, PABLO; COELHO, PAULO G. Nanomechanical Assessment of Bone Surrounding Implants Loaded for 3 Years in a Canine Experimental Model. JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, v. 76, n. 1, p. 71-79, JAN 2018. Web of Science Citations: 2.

BORDIN, DIMORVAN; BERGAMO, EDMARA T. P.; BONFANTE, ESTEVAM A.; FARDIN, VINICIUS P.; COELHO, PAULO G. Influence of platform diameter in the reliability and failure mode of extra short dental implants. JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS, v. 77, p. 470-474, JAN 2018. Web of Science Citations: 2.

CACERES, EDUARDO A.; SAMPAIO, CAMILA S.; ATRIA, PABLO J.; MOURA, HELORA; GIANNINI, MARCELO; COELHO, PAULO G.; HIRATA, RONALDO. Void and gap evaluation using microcomputed tomography of different fiber post cementation techniques. JOURNAL OF PROSTHETIC DENTISTRY, v. 119, n. 1, p. 103-107, JAN 2018. Web of Science Citations: 3.

BORDIN, DIMORVAN; BERGAMO, EDMARA T. P.; FARDIN, VINICIUS P.; COELHO, PAULO G.; BONFANTE, ESTEVAM A. Fracture strength and probability of survival of narrow and extra-narrow dental implants after fatigue testing: In vitro and in silico analysis. JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS, v. 71, p. 244-249, JUL 2017. Web of Science Citations: 5.

SAMPAIO, CAMILA S.; BARBOSA, JOAO MALTA; CACERES, EDUARDO; RIGO, LINDIANE C.; COELHO, PAULO G.; BONFANTE, ESTEVAM A.; HIRATA, RONALDO. Volumetric shrinkage and film thickness of cementation materials for veneers: An in vitro 3D microcomputed tomography analysis. JOURNAL OF PROSTHETIC DENTISTRY, v. 117, n. 6, p. 784-791, JUN 2017. Web of Science Citations: 7.

VIDOTT, HUGO A.; CARVALHO, RICARDO M.; COELHO, PAULO G.; ZAMBUZZI, WILLIAN F.; BONFANTE, GERSON; DO VALLE, ACCACIO L.; BONFANTE, ESTEVAM A. Effect of Mechanical Fatigue on he Bond Between Zirconia and Composite Cement. Journal of Adhesive Dentistry, v. 19, n. 5, p. 401-408, 2017. Web of Science Citations: 1.

FARDIN, VINICIUS P.; DE PAULA, VITOR GUARCONI; BONFANTE, ESTEVAM A.; COELHO, PAULO G.; BONFANTE, GERSON. Lifetime prediction of zirconia and metal ceramic crowns loaded on marginal ridges. Dental Materials, v. 32, n. 12, p. 1543-1554, DEC 2016. Web of Science Citations: 6.

ANCHIETA, RODOLFO B.; MACHADO, LUCAS S.; HIRATA, RONALDO; COELHO, PAULO G.; BONFANTE, ESTEVAM A. Survival and failure modes: platform-switching for internal and external hexagon cemented fixed dental prostheses. European Journal of Oral Sciences, v. 124, n. 5, p. 490-497, OCT 2016. Web of Science Citations: 2.