| Grant number: | 16/06185-0 |
| Support Opportunities: | Regular Research Grants |
| Start date: | September 01, 2016 |
| End date: | February 28, 2019 |
| Field of knowledge: | Biological Sciences - Parasitology - Helminthology of Parasites |
| Principal Investigator: | Fabiana Martins de Paula |
| Grantee: | Fabiana Martins de Paula |
| Host Institution: | Instituto de Medicina Tropical de São Paulo (IMT). Universidade de São Paulo (USP). São Paulo , SP, Brazil |
| Associated researchers: | Julia Maria Costa Cruz ; Marcelo Andreetta Corral ; Maria Cristina Carvalho Do Espírito Santo ; Priscilla Duarte Marques Fonseca ; Ronaldo Cesar Borges Cryschek ; William de Castro Borges |
| Associated scholarship(s): | 18/06129-9 - Maintenance of evolutionary stages of Strongyloides venezuelensis, BP.TT |
Abstract
The strongyloidiasis is a parasitic disease caused by the nematode Strongyloides stercoralis. This helminths can take extreme gravity, culminating in death, especially in immunocompromised patients. Increasingly it has used Strongyloides venezuelensis species as an alternative for the production of antigens, in addition to studies on aspects of host-parasite relationship. Using proteomics, this study to evaluate the expression of proteins in different developmental stages from S. venezuelensis, and identify immunogenic proteins filariform larvae of S. venezuelensis recognized by anibodies presente in serum samples from experimentally infected rats. (AU)
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