²-alanine supplementation associated to high-intensity interval training on performance and central and peripheral fatigue processes during repeated sprints

• Grant number: 16/11076-6
• Support Opportunities: Regular Research Grants
• Duration: November 01, 2016 - October 31, 2018
• Field of knowledge: Health Sciences - Physical Education
• Principal Investigator: Alessandro Moura Zagatto
• Grantee: Alessandro Moura Zagatto
• Host Institution: Faculdade de Ciências (FC). Universidade Estadual Paulista (UNESP). Campus de Bauru. Bauru , SP, Brazil
• Associated researchers: Adelino Sanchez Ramos da Silva ; Johnny Padulo

Abstract

The carnosine has been considered to have a relevant role in intramuscular buffering during exercise, increasing the muscle buffering capacity around 12% to 17% in fast contraction muscle fiber. However, the carnosine synthesis on muscle tissue is limited by ²-alanine amino acids availability. In recent studies with ²-alanine supplementation have been reported the increase of performance during anaerobic efforts, evidencing the possible effect of ²-alanine supplementation during exercise. Therefore, the purpose of this study is to investigate the effect of ²-alanine supplementation associated with high-intensity interval training on performance, muscular buffering capacity and enzymes of glycolysis pathway, and and on occurrence of central and peripheral fatigue process during repeated sprints. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

MILIONI, FABIO; BONETTI DE POLI, RODRIGO ARAUJO; SAUNDERS, BRYAN; GUALANO, BRUNO; DA ROCHA, ALISSON L.; RAMOS DA SILVA, ADELINO SANCHEZ; GUERRERO MULLER, PAULO DE TARSO; ZAGATTO, ALESSANDRO MOURA. Effect of beta-alanine supplementation during high-intensity interval training on repeated sprint ability performance and neuromuscular fatigue. Journal of Applied Physiology, v. 127, n. 6, p. 1599-1610, DEC 2019. (16/11076-6, 16/50438-0, 16/17836-2, 16/02683-6)

NORBERTO, MATHEUS SILVA; BARBIERI, RICARDO AUGUSTO; BERTUCCI, DANILO RODRIGUES; GOBBI, RONALDO BUCKEN; CAMPOS, EDUARDO ZAPATERRA; ZAGATTO, ALESSANDROU MOURA; DE FREITAS, ELLEN CRISTINI; PAPOTI, MARCELO. Beta alanine supplementation effects on metabolic contribution and swimming performance. JOURNAL OF THE INTERNATIONAL SOCIETY OF SPORTS NUTRITION, v. 17, n. 1, JUL 25 2020. (16/12781-5, 13/15322-3, 16/11076-6)