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Study of the biotransformation of phenylpropanoids dimers by actinomycetes from caatinga

Grant number: 16/23685-7
Support type:Program for Research on Bioenergy (BIOEN) - Regular Program Grants
Duration: April 01, 2017 - March 31, 2019
Field of knowledge:Biological Sciences - Microbiology - Applied Microbiology
Principal Investigator:Suzan Pantaroto de Vasconcellos
Grantee:Suzan Pantaroto de Vasconcellos
Home Institution: Instituto de Ciências Ambientais, Químicas e Farmacêuticas (ICAQF). Universidade Federal de São Paulo (UNIFESP). Campus Diadema. Diadema , SP, Brazil
Assoc. researchers:Ana Claudia Trocoli Torrecilhas ; Andre Luiz Meleiro Porto ; João Henrique Ghilardi Lago ; Wagner Luiz Batista

Abstract

Actinobacteria are known about their abilities to produce many bioactive compounds, including enzymes with multiple biotechnological applications. In this context, lignocellulolytic enzymes are one of the most explored aiming their application in industries that use lignocellulose as raw material. In addition to the cellulose, lignin is also considered as the most abundant polymers at Earth. Structurally, lignin is basically composed by phenylpropanoid compounds and lignans, which are being described about their pharmacological properties, involving cytostatic, antitumor and antiparasitic activities. The present research proposal was elaborated based on previous results obtained by the involved groups, allied to emerging questions related to efficient drugs for treatment of neglected diseases, as well as for the sustainable production of biofuels using vegetal biomass. In this sense, the investigation will be divided in two distinct moments, which are connected in the evaluation of the same substrates for microbial metabolism, some phenylpropanoids from Nectandra neucantha. (AU)

Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
MARTINHO, VIVIAN; DOS SANTOS LIMA, LIDIANE MARIA; BARROS, CAROLINE ALMEIDA; FERRARI, VITOR BAPTISTA; ZAMBRANO PASSARINI, MICHEL RODRIGO; SANTOS, LEONARDO ANDRE; DE SOUZA SEBASTIANES, FERNANDA LUISA; LACAVA, PAULO TEIXEIRA; DE VASCONCELLOS, SUZAN PANTAROTO. Enzymatic potential and biosurfactant production by endophytic fungi from mangrove forest in Southeastern Brazil. AMB EXPRESS, v. 9, n. 1 AUG 19 2019. Web of Science Citations: 0.

Please report errors in scientific publications list by writing to: cdi@fapesp.br.