Arrabidaea chica incorporate into the phosphoric acid or primer of a conventional adhesive system or as a dentin pretreatment in aqueos solution: physical properties evaluation of the solutions and influence on dentin physico-mechanical properies

• Grant number: 17/08082-7
• Support Opportunities: Regular Research Grants
• Start date: November 01, 2017
• End date: October 31, 2019
• Field of knowledge: Health Sciences - Dentistry - Dental Materials
• Principal Investigator: Roberta Tarkany Basting Höfling
• Grantee: Roberta Tarkany Basting Höfling
• Host Institution: Centro de Pesquisas Odontológicas São Leopoldo Mandic. Faculdade São Leopoldo Mandic (SLMANDIC). Sociedade Regional de Ensino e Saúde S/S Ltda (SRES). Campinas , SP, Brazil

Abstract

The aim of this study is to evaluate; 1) the long-term bond strength, failure mode and interface micromorphology of a three-step conventional adhesive system to dentin submitted to pretreatment with 2.5% Arrabidaea chica extract or when incorporated into the phosphoric acid or into the primer of the adhesive system after 24 hours and 12 months; 2) physical-chemical properties of aqueous solution, acid and primer incorporated with 2.5% Arrabidaea chica extract: pH, degree of conversion, sorption and solubility, particles distribution, zeta potential, polidispersitivity and extract release from incorporate primer; 3) dentin matrix stability (stiffness) and dentin metalloproteinases inhibition (by in situ zymograph) after dentin pretreatment with aqueous solution of 2.5% Arrabidaea chica extract or when incorporated into the phosphoric acid or into the primer of the adhesive system . Third sound human molars will be prepared for the microtensile bond strength tests, failure mode, interface micromorphology and in situ zymograph. Dentin specimens (beams) will be prepared for the dentin matrix stability (stiffness) evaluation. Adhesive system specimens incorporate or not with the Arrabidaea chica extract will be prepared for the pH, degree of conversion, sorption and solubility, particles distribution, zeta potential, polidispersitivity and extract release from incorporate primer analyses. According to the presence of normality distribution of the data or not, parametric or non-parametric statistical tests will be applied, using a significance level of 5%. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

MENDES, BRUNA NOVAES; BRIDI, ENRICO COSER; FRANCA, FABIANA MANTOVANI GOMES; TURSSI, CECILIA PEDROSO; DO AMARAL, FLAVIA LUCISANO BOTELHO; BASTING, ROSANNA TARKANY; SOUSA, ILZA MARIA DE OLIVEIRA; DA SILVA, TANIA MARA; GONCALVES, SERGIO EDUARDO DE PAIVA; FOGLIO, MARY ANN; et al. Polyphenol-enriched extract of Arrabidaea chica used as a dentin pretreatment or incorporated into a total-etching adhesive system: Effects on bonding stability and physical characterization. Materials Science & Engineering C-Materials for Biological Applications, v. 116, NOV 2020. (17/08082-7, 16/04343-8)

FONSECA, ISABELLE SILVEIRA; CASAROTTO, RAFAEL; BRIDI, ENRICO COSER; BASTING, ROSANNA TARKANY; GOMES FRANCA, FABIANA MANTOVANI; TURSSI, CECILIA PEDROSO; BOTELHO DO AMARAL, FLAVIA LUCISANO; DE OLIVEIRA SOUSA, ILZA MARIA; FOGLIO, MARY ANN; BASTING, ROBERTA TARKANY. Polyphenol-enriched extract incorporated into a total-etch adhesive system: Effect on water sorption and solubility, extract compound release and dentin enzymatic activity over time. INTERNATIONAL JOURNAL OF ADHESION AND ADHESIVES, v. 113, MAR 2022. (17/08082-7)