Synthesis and Planning of reciprocally prodrugs used to prevent UV radiation damage.

• Grant number: 10/03825-2
• Support Opportunities: Scholarships in Brazil - Master
• Start date: August 01, 2010
• End date: June 30, 2012
• Field of knowledge: Health Sciences - Pharmacy
• Principal Investigator: Chung Man Chin
• Grantee: Paulo Renato Yamasaki
• Host Institution: Faculdade de Ciências Farmacêuticas (FCFAR). Universidade Estadual Paulista (UNESP). Campus de Araraquara. Araraquara , SP, Brazil

Abstract

Photoaging and skin câncer are know pathologies associated to UV radiation on the body. Sunscreens are designed with the aim of reducing the harmful effects of UV radiation, however the incidence of skin cancer increases every year around the world, requiring new strategies to reduce the UV damage. Given these facts, the purpose of this study is to synthesize a mutual prodrug of a sunscreen and an antioxidant molecule in order to reduce the harmful effects of UV radiation.