Locomotor behavior, clinical parameters, falls incidence, and physical activity level in Parkinson disease patients. A two-year longitudinal study.

• Grant number: 10/07040-0
• Support Opportunities: Scholarships in Brazil - Doctorate
• Effective date (Start): August 01, 2010
• Effective date (End): January 31, 2015
• Field of knowledge: Health Sciences - Physical Education
• Principal Investigator: Lilian Teresa Bucken Gobbi
• Grantee: Rodrigo Vitório
• Host Institution: Instituto de Biociências (IB). Universidade Estadual Paulista (UNESP). Campus de Rio Claro. Rio Claro , SP, Brazil
• Associated scholarship(s): 12/03456-2 - How is visual information used for the control of locomotion in patients with Parkinson's Disease?, BE.EP.DR

Abstract

Introduction: The progression of clinical and gait parameters, occurrence of falls and level of physical activity has not been jointly examined in patients with Parkinson's disease (PD). Data of this nature can serve as important tool in order to optimize the design of pharmacological and nonpharmacological interventions. Objective: To analyze the progression of impairments on gait, clinical parameters, and the occurrence of falls in patients with idiopathic PD over a period of two years, considering the level of physical activity as intervenient factor. Method: Participants will include patients with PD, rated between stages 1 and 3 on Hoehn & Yahr, and healthy elderly with age, gender and similar anthropometric characteristics. The experimental design will include assessment in 3 moments (Baseline, Follow-up 1 and Follow Up 2), with an interval of one year between each two moments. Initially, patients will be clinically evaluated by a neuropsychiatrist doctor and then both groups will undergo assessment of locomotor behavior (kinematic and kinetic analysis of the task of free walking and obstacle avoidance), the occurrence of falls (prospective method ), and level of physical activity (pedometer use). Statistical analysis will include ANOVAs, MANOVAs, Friedman test, ANCOVAs and Pearson correlation and Spearman tests.

Scientific publications

(6)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

ORCIOLI-SILVA, DIEGO; VITORIO, RODRIGO; LIRANI-SILVA, ELLEN; ROCHA SANTOS, PAULO CEZAR; BERETTA, VICTOR SPIANDOR; BUCKEN GOBBI, LILIAN TERESA. Objective measures of unobstructed walking and obstacle avoidance in Parkinson's disease subtypes. GAIT & POSTURE, v. 62, p. 405-408, MAY 2018. (10/07040-0, 14/22308-0, 13/27032-0)

VITORIO, RODRIGO; LIRANI-SILVA, ELLEN; BAPTISTA, ANDRE MACARI; BARBIERI, FABIO AUGUSTO; ROCHA DOS SANTOS, PAULO CEZAR; TEIXEIRA-ARROYO, CLAUDIA; BUCKEN GOBBI, LILIAN TERESA. Disease severity affects obstacle crossing in people with Parkinson's disease. GAIT & POSTURE, v. 40, n. 1, p. 266-269, MAY 2014. (10/07040-0)

BERETTA, VICTOR SPIANDOR; BARBIERI, FABIO AUGUSTO; ORCIOLI-SILVA, DIEGO; ROCHA DOS SANTOS, PAULO CEZAR; SIMIELI, LUCAS; VITORIO, RODRIGO; BUCKEN GOBBI, LILIAN TERESA. Can Postural Control Asymmetry Predict Falls in People With Parkinson's Disease?. MOTOR CONTROL, v. 22, n. 4, p. 449-461, OCT 2018. (13/00925-4, 10/07040-0, 12/24040-9)

NOBREGA-SOUSA, PRISCILA; ORCIOLI-SILVA, DIEGO; LIRANI-SILVA, ELLEN; BERETTA, VICTOR SPIANDOR; VITORIO, RODRIGO; BUCKEN GOBBI, LILIAN TERESA. Usual walking and obstacle avoidance are influenced by depressive and anxiety symptoms in patients with Parkinson's disease. Geriatrics & Gerontology International, v. 19, n. 9, JULY 2019. (14/22308-0, 10/07040-0)

DA CONCEICAO, NUBIA RIBEIRO; DE SOUSA, PRISCILA NOBREGA; PEREIRA, MARCELO PINTO; BUCKEN GOBBI, LILIAN TERESA; VITORIO, RODRIGO. Utility of center of pressure measures during obstacle crossing in prediction of fall risk in people with Parkinson's disease. HUMAN MOVEMENT SCIENCE, v. 66, p. 1-8, AUG 2019. (14/22308-0, 10/07040-0)

VITORIO, RODRIGO; GOBBI, LILIAN T. B.; LIRANI-SILVA, ELLEN; MORAES, RENATO; ALMEIDA, QUINCY J.. Synchrony of gaze and stepping patterns in people with Parkinson's disease. Behavioural Brain Research, v. 307, p. 159-164, JUL 1 2016. (10/07040-0, 12/03456-2)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

VITÓRIO, Rodrigo. Comportamento locomotor, quadro clínico, incidência de quedas e nível de atividade física em pacientes com doença de Parkinson: um estudo longitudinal de dois anos. 2015. Doctoral Thesis - Universidade Estadual Paulista (Unesp). Instituto de Biociências. Rio Claro Rio Claro.