Asymmetry in postural control in fallers and non-fallers elderly with Parkinson's disease in different static positions

• Grant number: 13/00925-4
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Effective date (Start): April 01, 2013
• Effective date (End): March 31, 2015
• Field of knowledge: Health Sciences - Physical Education
• Principal Investigator: Lilian Teresa Bucken Gobbi
• Grantee: Victor Spiandor Beretta
• Host Institution: Instituto de Biociências (IB). Universidade Estadual Paulista (UNESP). Campus de Rio Claro. Rio Claro , SP, Brazil

Abstract

The posture control appears to be asymmetric in patients with Parkinson's disease (PD), which is a major risk of falls in this population. However, the asymmetry in postural control among elderly fallers and non-fallers with PD is poorly studied. The aim of the study is to analyze the asymmetry in postural control in different static positions of elderly fallers and non-fallers with PD. Seventh elderly with PD will participate in this study. Firstly, the participants will be assessed for the clinical aspects and the fall incidence by prospective monitoring weekly for a total of 6 months. Then, it will be selected, among the participants, 12 elderly fallers and 12 elderly non-fallers to evaluate the postural control. Patients will be evaluated in "ON" state of the medication by two force platforms in three conditions: bipedal support, one leg support, and tandem position. Each participant will perform 3 trials of 30 s for each condition. In the last two conditions, each participant will perform 3 trials for each leg. In all conditions, the participants will be instructed to stand erect with their gaze directed at a target positioned at 1 m from the participant and the participant's eye level. The displacement, area, average speed, and root mean square of centre of pressure for each condition will be analyzed and compared by two-way ANOVAs with factor for the group (fallers vs. non-fallers) and asymmetry (most affected limb vs. less affected limb, which will be determined by the asymmetry index by UPDRS). If there is the interaction between factors, post hoc Tukey tests will be used to determine the relationships among the factors. (AU)

Scientific publications

(5)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

BARBIERI, FABIO AUGUSTO; SIMIELI, LUCAS; ORCIOLI-SILVA, DIEGO; BAPTISTA, ANDRE MACARI; PESTANA, MAYARA BORKOWSKE; BERETTA, VICTOR SPIANDOR; ROCHA DOS SANTOS, PAULO CEZAR; BUCKEN GOBBI, LILIAN TERESA. Obstacle Avoidance Increases Asymmetry of Crossing Step in Individuals With Parkinson's Disease and Neurologically Healthy Individuals. JOURNAL OF MOTOR BEHAVIOR, v. 50, n. 1, p. 17-25, 2018. (13/00925-4)

BERETTA, VICTOR SPIANDOR; BARBIERI, FABIO AUGUSTO; ORCIOLI-SILVA, DIEGO; ROCHA DOS SANTOS, PAULO CEZAR; SIMIELI, LUCAS; VITORIO, RODRIGO; BUCKEN GOBBI, LILIAN TERESA. Can Postural Control Asymmetry Predict Falls in People With Parkinson's Disease?. MOTOR CONTROL, v. 22, n. 4, p. 449-461, OCT 2018. (13/00925-4, 10/07040-0, 12/24040-9)

BERETTA, VICTOR SPIANDOR; BUCKEN GOBBI, LILIAN TERESA; LIRANI-SILVA, ELLEN; SIMIELI, LUCAS; ORCIOLI-SILVA, DIEGO; BARBIERI, FABIO AUGUSTO. Challenging Postural Tasks Increase Asymmetry in Patients with Parkinson's Disease. PLoS One, v. 10, n. 9, SEP 14 2015. (13/00925-4)

BARBIERI, FABIO A.; POLASTRI, PAULA F.; BAPTISTA, ANDRE M.; LIRANI-SILVA, ELLEN; SIMIELI, LUCAS; ORCIOLI-SILVA, DIEGO; BERETTA, VICTOR S.; GOBBI, LILIAN T. B.. Effects of disease severity and medication state on postural control asymmetry during challenging postural tasks in individuals with Parkinson's disease. HUMAN MOVEMENT SCIENCE, v. 46, p. 96-103, APR 2016. (13/00925-4, 12/24040-9)

BARBIERI, FABIO AUGUSTO; CARPENTER, MARK; BERETTA, VICTOR SPIANDOR; ORCIOLI-SILVA, DIEGO; SIMIELI, LUCAS; VITORIO, RODRIGO; BUCKEN GOBBI, LILIAN TERESA. Postural control, falls and Parkinson's disease: Are fallers more asymmetric than non-fallers?. HUMAN MOVEMENT SCIENCE, v. 63, p. 129-137, FEB 2019. (13/00925-4, 12/24040-9)