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Evaluation of two surgical adhesives to the ovariectomy in rabbits(Part 2)

Grant number: 11/22801-0
Support type:Scholarships in Brazil - Scientific Initiation
Effective date (Start): March 01, 2012
Effective date (End): December 31, 2012
Field of knowledge:Agronomical Sciences - Veterinary Medicine - Animal Clinics and Surgery
Principal researcher:Cristiane dos Santos Honsho
Grantee:Cynthia Marchiori Bueno
Home Institution: Coordenadoria Adjunta de Graduação. Universidade de Franca (UNIFRAN). Franca , SP, Brazil

Abstract

The development of mass sterilization programs implies the adoption of surgical procedures at low cost, fast execution and good postoperative recovery. Thus, it is proposed in this study to evaluate the feasibility of implementation of two surgical adhesives, n-butyl-cyanoacrylate (Part 1, a student Aline Silva Santana) and 2-octyl-cyanoacrylate (Part 2, Marchiori student Cynthia Bueno), in ovariectomy of rab and thebits muscle and skin closure, as an alternative to the use of suture material for campaigns castration of dogs and cats. Will be formed three groups of eight rabbits each, which will be used for ligation of the pedicle, closing muscle and skin, nylon (CG, n-08), n-butyl-cyanoacrylate (GB, n = 08) and 2-octyl-cyanoacrylate (GO, n = 08), respectively. With the aid of stopwatch, the time spent will be demarcated between the beginning of the procedure (skin incision) and end (complete closure of the skin), the time for pedicle ligation, closure of the muscles and skin. The surgical wound will be inspected daily for 10 days, for healing and dehiscence points. The animals will suffer euthanasia, and the abdominal cavity will be evaluated macroscopically for the presence of adhesions and inflammation and uterine pedicles and remaining will be evaluated by histology. Results are presented by descriptive analysis.